Continuous rhamnolipid production with integrated product removal by foam fractionation and magnetic separation of immobilized Pseudomonas aeruginosa

Biotechnology Progress

Volumn 27, Issue 3, 2011, Pages 706-716

  Heyd, M ^a   Franzreb, M ^a   Berensmeier, S ^a,b  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Biosurfactants; Continuous production; Foam fractionation; Process integration; Pseudomonas aeruginosa; Rhamnolipids

Indexed keywords

BIO-SURFACTANTS; CONTINUOUS PRODUCTION; FOAM FRACTIONATION; PROCESS INTEGRATION; PSEUDOMONAS AERUGINOSA; RHAMNOLIPIDS;

BACTERIA; BIOMOLECULES; BIOREACTORS; MAGNETIC SEPARATION; SURFACE ACTIVE AGENTS;

FRACTIONATION;

GLYCOLIPID; RHAMNOLIPID; SURFACTANT;

ARTICLE; BIOREACTOR; BIOSYNTHESIS; CYTOLOGY; FRACTIONATION; IMMOBILIZED CELL; IMMUNOMAGNETIC SEPARATION; METABOLISM; MICROBIOLOGY; PSEUDOMONAS AERUGINOSA; TECHNIQUE;

BIOREACTORS; CELLS, IMMOBILIZED; CHEMICAL FRACTIONATION; GLYCOLIPIDS; IMMUNOMAGNETIC SEPARATION; METHODS; PSEUDOMONAS AERUGINOSA; SURFACE-ACTIVE AGENTS;

BACTERIA (MICROORGANISMS); PSEUDOMONAS AERUGINOSA;

EID: 79958271441     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.607     Document Type: Article

References (45)

1. Lin SC. Biosurfactants: recent advances. J Chem Technol Biotechnol. 1996; 66: 109-120.
2. Lang S. Biological amphiphiles (microbial biosurfactants). Curr Opin Colloid Interface Sci. 2002; 7: 12-20.
3. Nitschke M, Costa SGVAO, Contiero J. Rhamnolipid surfactants: an update on the general aspects of these remarkable biomolecules. Biotechnol Prog. 2005; 21: 1593-1600.
4. Desai JD, Banat IM. Microbial production of surfactants and their commercial potential. Microbiol Mol Biol Rev. 1997; 61: 47-64.
5. Banat IM, Makkar RS, Cameotra SS. Potential commercial applications of microbial surfactants. Appl Microbiol Biotechnol. 2000; 53: 495-508.
6. Kitamoto D, Isoda H, Nakahara T. Functions and potential applications of glycolipid biosurfactants-from energy-saving materials to gene delivery carriers. J Biosci Bioeng. 2002; 94: 187-201.
7. Deziel E, Lepine F, Dennie D, Boismenu D, Mamer OA, Villemur R. Liquid chromatography/mass spectrometry analysis of mixtures of rhamnolipids produced by Pseudomonas aeruginosa strain 57RP grown on mannitol or naphthalene. Biochim Biophys Acta. 1999; 1440: 244-252.
8. Haba E, Pinazo P, Jauregui O, Espuny MJ, Infante MR, Manresa A. Physicochemical characterization and antimicrobial properties of rhamnolipids produced by Pseudomonas aeruginosa 47T2 NCBIM 40044. Biotechnol Bioeng. 2003; 81: 316-322.
9. Gunther NW, Nunez A, Fett W, Solaiman DKY. Production of rhamnolipids by Pseudomonas chlororaphis, a nonpathogenic bacterium. Appl Environ Microbiol. 2005; 71: 2288-2293.
10. Syldatk C, Lang S, Matulovic U, Wagner F. Production of four interfacial active rhamnolipids from n-alkanes or glycerol by resting cells of Pseudomonas species DSM 2874. Z Naturforsch C. 1985; 40: 61-67.
11. Gruber T. Verfahrenstechnische Aspekte der kontinuierlichen Produktion von Biotensiden am Beispiel der Rhamnolipide. PhD Thesis, Universität Stuttgart, Germany, 1991.
12. Koch V, Rüffer H-M, Schügerl K, Innertsberger E, Menzel H, Weis J. Effect of antifoam agents on the medium and microbial cell properties and process performance in small and large reactors. Process Biochem. 1995; 30: 435-446.
13. Mulligan CN, Gibbs BF. Recovery of biosurfactants by ultrafiltration. J Chem Technol Biotechnol. 1990; 47: 23-29.
14. Fiechter A. Integrated systems for biosurfactant synthesis. Pure Appl Chem. 1992; 64: 1739-1743.
15. Van Hamme JD, Singh A, Ward OP. Physiological aspects: part 1 in a series of papers devoted to surfactants in microbiology and biotechnology. Biotechnol Adv. 2006; 24: 604-620.
16. Cooper DG, Macdonald CR, Duff SJB, Kosaric N. Enhanced production of surfactin from Bacillus subtilis by continuous product removal and metal cation additions. Appl Environ Microbiol. 1981; 42: 408-412.
17. Matulovic U. Verfahrensentwicklung zur Herstellung grenzflächenaktiver Rhamnolipide mit immobilisierten Zellen von Pseudomonas spec. DSM 2874. PhD Thesis, TU Braunschweig, Germany, 1987.
18. Chen CY, Baker SC, Darton RC. Batch production of biosurfactant with foam fractionation. J Chem Technol Biotechnol. 2008; 81: 1923-1931.
19. Dubey KV, Juwarkar AA. Adsorption-desorption process using wood-based activated carbon for recovery of biosurfactant from fermented distillery wastewater. Biotechnol Prog. 2005; 21: 860-867.
20. Brown AK, Kaul A, Varley J. Continuous foaming for protein recovery. I. Recovery of beta-casein. Biotechnol Bioeng. 1999; 62: 278-290.
21. Davis DA, Lynch HC, Varley J. The application of foaming for the recovery of Surfactin from B. subtilis ATCC 21332 cultures. Enzyme Microbiol Technol. 2002; 28: 346-354.
22. Hubbuch JJ, Thomas ORT. High-gradient magnetic affinity separation of trypsin from porcine pancreatin. Biotechnol Bioeng. 2002; 79: 301-313.
23. Meyer A, Berensmeier S, Franzreb M. Direct capture of lactoferrin from whey using magnetic micro-ion exchangers in combination with high-gradient magnetic separation. React Funct Polym. 2007; 67: 1577-1588.
24. Schultz N, Syldatk C, Franzreb M, Hobley TJ. Integrated processing and multiple re-use of immobilised lipase by magnetic separation technology. J Biotechnol. 2007; 132: 202-208.
25. Hoffmann C, Franzreb M, Holl WH. A novel high-gradient magnetic separator (HGMS) design for biotech applications. IEEE Trans Appl Supercond. 2002; 12: 963-966.
26. Syldatk C. Mikrobielle Bildung und Charakterisierung grenzflächenaktiver Rhamnolipide aus Pseudomonas spec. DSM 2874. PhD Thesis, TU Braunschweig, Germany, 1984.
27. Wilms B, Hauck A, Reuss M, Syldatk C, Mattes R, Siemann M, Altenbuchner J. High-cell-density fermentation for production of L-N-carbamoylase using an expression system based on the Escherichia coli rhaBAD promoter. Biotechnol Bioeng. 2001; 73: 95-103.
28. Poncelet D, Babak V, Dulieu C, Picot A. A physico-chemical approach to production of alginate beads by emulsification-internal ionotropic gelation. Colloids Surf A. 1999; 155: 171-176.
29. Heyd M, Kohnert A, Tan T-H, Nusser M, Kirschhöfer F, Brenner-Weiss G, Franzreb M, Berensmeier S. Development and trends of biosurfactant analysis and purification using rhamnolipids as an example. Anal Bioanal Chem. 2008; 391: 1579-1590.
30. Weaire DL, Hutzler S. The Physics of Foam. Oxford: Oxford University Press, 1999.
31. Morgan G, Wiesmann U. Single and multistage foam fractionation of rinse water with alkyl ethoxylate surfactants. Sep Sci Technol. 2001; 36: 2247-2263.
32. Ochsner UA, Koch A, Fiechter A, Reiser J. Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. J Bacteriol. 1994; 176: 2044-2054.
33. Ochsner UA, Reiser J. Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. Proc Natl Acad Sci USA. 1995; 92: 6424-6428.
34. Riesenberg D, Guthke R. High-cell-density cultivation of microorganisms. Appl Microbiol Biotechnol. 1999; 51: 422-430.
35. Lee SY. High cell-density culture of Escherichia coli. Trends Biotechnol. 1996; 14: 98-105.
36. Haba E, Espuny MJ, Busquets M, Manresa A. Screening and production of rhamnolipids by Pseudomonas aeruginosa 47T2 NCIB 40044 from waste frying oils. J Appl Microbiol. 2000; 88: 379-387.
37. Abalos A, Maximo F, Manresa MA, Bastida J. Utilization of response surface methodology to optimize the culture media for the production of rhamnolipids by Pseudomonas aeruginosa AT10. J Chem Technol Biotechnol. 2002; 77: 777-784.
38. Lee KM, Hwang SH, Ha SD, Jang JH, Lim DJ, Kong JY. Rhamnolipid production in batch and fed-batch fermentation using Pseudomonas aeruginosa BYK-2 KCTC 18012P. Biotechnol Bioprocess Eng. 2004; 9: 267-273.
39. Tahzibi A, Kamal F, Assadi MM. Improved production of rhamnolipids by Pseudomonas aeruginosa mutant. Iran Biomed J. 2004; 8: 25-31.
40. Heyd M, Weigold P, Franzreb M, Berensmeier S. Influence of different magnetites on properties of magnetic Pseudomonas aeruginosa immobilizates used for biosurfactant production. Biotechnol Prog. 2009; 25: 1620-1629.
41. Arino S, Marchal R, Vandecasteele J-P. Identification and production of a rhamnolipidic biosurfactant by a Pseudomonas species. Appl Microbiol Biotechnol. 1996; 45: 162-168.
42. Giani C, Wullbrandt D, Rothert R, Meiwes J. Pseudomonas aeruginosa and its use in process for the biotechnological preparation of L-rhamnose. Germany: Hoechst AG, Frankfurt am Main. US Patent 5, 658, 793 (1997).
43. Sim L, Ward OP, Li Z-Y. Production and characterisation of a biosurfactant isolated from Pseudomonas aeruginosa UW-1. J Ind Microbiol Biotechnol. 1997; 19: 232-238.
44. Muller MM, Hormann B, Syldatk C, Hausmann R. Pseudomonas aeruginosa PAO1 as a model for rhamnolipid production in bioreactor systems. Appl Microbiol Biotechnol. 2010; 87: 167-174.
45. Morgan G. Foam Fractionation of Surfactant Solutions. Fortschrittsberichte VDI Reihe 3. Düsseldorf: VDI Verlag; 2004; 811: 124.