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Volumn 32, Issue 6, 2011, Pages 913-920

Butyrate suppresses mRNA increase of osteopontin and cyclooxygenase-2 in human colon tumor tissue

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; CYCLOOXYGENASE 2; MESSENGER RNA; OSTEOPONTIN; PROSTAGLANDIN E2;

EID: 79958205596     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr061     Document Type: Article
Times cited : (24)

References (62)
  • 2
    • 0038637789 scopus 로고    scopus 로고
    • Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study
    • Bingham,S.A. et al. (2003) Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition EPIC): an observational study. Lancet, 361, 1496-1501.
    • (2003) Lancet , vol.361 , pp. 1496-1501
    • Bingham, S.A.1
  • 3
    • 35448966378 scopus 로고    scopus 로고
    • World Cancer Research Fund and American Institute for Cancer:A Research. American Institute for Cancer Research, Washington, DC
    • World Cancer Research Fund and American Institute for Cancer Research. (2007) Food, Nutrition, Physical Activity and the Prevention of Cancer: A Global Perspective. American Institute for Cancer Research, Washington, DC.
    • (2007) Food, Nutrition, Physical Activity and the Prevention of Cancer: A Global Perspective
  • 4
    • 0346749816 scopus 로고    scopus 로고
    • Butyrate is only one of several growth inhibitors produced during gut flora-mediated fermentation of dietary fibre sources
    • Beyer-Sehlmeyer,G. et al. (2003) Butyrate is only one of several growth inhibitors produced during gut flora-mediated fermentation of dietary fibre sources. r. J. Nutr., 90, 1057-1070.
    • (2003) Br. J. Nutr. , vol.90 , pp. 1057-1070
    • Beyer-Sehlmeyer, G.1
  • 5
    • 22344443983 scopus 로고    scopus 로고
    • Butyrate may enhance toxicological defence in primary, adenoma and tumor human colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics
    • Pool-Zobel,B.L. et al. (2005) Butyrate may enhance toxicological defence in primary, adenoma and tumor human colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics. Carcinogenesis, 26, 1064-1076.
    • (2005) Carcinogenesis , vol.26 , pp. 1064-1076
    • Pool-Zobel, B.L.1
  • 6
    • 68749119436 scopus 로고    scopus 로고
    • Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre
    • Scharlau,D. et al. (2009) Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary ibre. Mutat. Res. 682, 39-53.
    • (2009) Mutat. Res. , vol.682 , pp. 39-53
    • Scharlau, D.1
  • 7
    • 0033028423 scopus 로고    scopus 로고
    • Colonic epithelial cell activation and the paradoxical effects of butyrate
    • Gibson,P.R. et al. (1999) Colonic epithelial cell activation and the paradoxical effects of butyrate. Carcinogenesis, 20, 539-544.
    • (1999) Carcinogenesis , vol.20 , pp. 539-544
    • Gibson, P.R.1
  • 8
    • 0030606299 scopus 로고    scopus 로고
    • Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
    • Oshima,M. et al. (1996) Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell, 87, 803-809.
    • (1996) Cell , vol.87 , pp. 803-809
    • Oshima, M.1
  • 9
    • 17844388876 scopus 로고    scopus 로고
    • Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis
    • Wai,P.Y. et al. (2005) Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. arcinogenesis, 26, 741-751.
    • (2005) Carcinogenesis , vol.26 , pp. 741-751
    • Wai, P.Y.1
  • 10
    • 0036180475 scopus 로고    scopus 로고
    • Osteopontin-a molecule for all seasons
    • Mazzali,M. et al. (2002) Osteopontin-a molecule for all seasons. QJM, 95, 3-13.
    • (2002) QJM , vol.95 , pp. 3-13
    • Mazzali, M.1
  • 11
    • 0035671826 scopus 로고    scopus 로고
    • Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer
    • Fedarko,N.S. et al. (2001) Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin. Cancer Res., 7, 4060-4066.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 4060-4066
    • Fedarko, N.S.1
  • 12
    • 34548700819 scopus 로고    scopus 로고
    • Expression of osteopontin, a target gene of de-regulated Wnt signaling, predicts survival in colon cancer
    • Rohde,F. et al. (2007) Expression of osteopontin, a target gene of de-regulated Wnt signaling, predicts survival in colon cancer. Int. J. Cancer, 121, 1717-723.
    • (2007) Int. J. Cancer , vol.121 , pp. 1717-1723
    • Rohde, F.1
  • 13
    • 44649088833 scopus 로고    scopus 로고
    • Systemic endocrine instigation of indolent tumor growth requires osteopontin
    • McAllister,S.S. et al. (2008) Systemic endocrine instigation of indolent tumor growth requires osteopontin. Cell, 133, 994-1005.
    • (2008) Cell , vol.133 , pp. 994-1005
    • McAllister, S.S.1
  • 14
    • 38549097166 scopus 로고    scopus 로고
    • Osteopontin: regulation in tumor metastasis
    • Wai,P.Y. et al. (2008) Osteopontin: regulation in tumor metastasis. Cancer Metastasis Rev., 27, 103-118.
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 103-118
    • Wai, P.Y.1
  • 15
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: advances in eicosanoid biology
    • Funk,C.D. (2001) Prostaglandins and leukotrienes: advances in eicosanoid biology. Science, 294, 1871-1875.
    • (2001) Science , vol.294 , pp. 1871-1875
    • Funk, C.D.1
  • 16
    • 44249089281 scopus 로고    scopus 로고
    • COX-2 expression in sporadic colorectal adenomatous polyps is linked to adenoma characteristics
    • McLean,M.H. et al. (2008) COX-2 expression in sporadic colorectal adenomatous polyps is linked to adenoma characteristics. Histopathology, 52, 806-15.
    • (2008) Histopathology , vol.52 , pp. 806-815
    • McLean, M.H.1
  • 17
    • 11144224065 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer
    • Soumaoro,L.T. et al. (2004) Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer. Clin. Cancer Res., 10, 8465-471.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 8465-8471
    • Soumaoro, L.T.1
  • 18
    • 62349138124 scopus 로고    scopus 로고
    • The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
    • Greenhough,A. et al. (2009) The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis, 30, 377-386.
    • (2009) Carcinogenesis , vol.30 , pp. 377-386
    • Greenhough, A.1
  • 19
    • 25144513892 scopus 로고    scopus 로고
    • Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells
    • Lev-Ari,S. et al. (2005) Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells. Clin. Cancer Res., 11, 6738-6744.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6738-6744
    • Lev-Ari, S.1
  • 20
    • 51249084799 scopus 로고    scopus 로고
    • Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis
    • Zhao,J. et al. (2008) Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis. Gastroenterology, 135, 956-968.
    • (2008) Gastroenterology , vol.135 , pp. 956-968
    • Zhao, J.1
  • 21
    • 0344405771 scopus 로고    scopus 로고
    • Putative colon cancer risk factors damage global DNA and TP53 in primary human colon cells isolated from surgical samples
    • Schaeferhenrich,A. et al. (2003) Putative colon cancer risk factors damage global DNA and TP53 in primary human colon cells isolated from surgical samples. ood Chem. Toxicol., 41, 655-664.
    • (2003) Food Chem. Toxicol. , vol.41 , pp. 655-664
    • Schaeferhenrich, A.1
  • 22
    • 0031871001 scopus 로고    scopus 로고
    • Establishment of long-term primary cultures of human small and large intestinal epithelial cells
    • Rogler,G. et al. (1998) Establishment of long-term primary cultures of human small and large intestinal epithelial cells. Lab. Invest., 78, 889-890.
    • (1998) Lab. Invest. , vol.78 , pp. 889-890
    • Rogler, G.1
  • 23
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl,M.W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res., 29, e45.
    • (2001) Nucleic Acids Res. , vol.29
    • Pfaffl, M.W.1
  • 24
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford,M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. iochem., 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 25
    • 0029008617 scopus 로고
    • Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
    • Kargman,S.L. et al. (1995) Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res., 55, 2556-2559.
    • (1995) Cancer Res. , vol.55 , pp. 2556-2559
    • Kargman, S.L.1
  • 26
    • 0037012338 scopus 로고    scopus 로고
    • Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling
    • Agrawal,D. et al. (2002) Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. J. Natl Cancer Inst., 94, 13-521.
    • (2002) J. Natl Cancer Inst. , vol.94 , pp. 513-521
    • Agrawal, D.1
  • 27
    • 0036790471 scopus 로고    scopus 로고
    • Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response
    • Papafili,A. et al. (2002) Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. rterioscler. Thromb. Vasc. Biol., 22, 1631-1636.
    • (2002) Arterioscler. Thromb. Vasc. Biol. , vol.22 , pp. 1631-1636
    • Papafili, A.1
  • 28
    • 4644265056 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma/carcinoma cells
    • Zhang,Z.H. et al. (2004) Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma/carcinoma cells. World J. Gastroenterol., 10, 954-2957.
    • (2004) World J. Gastroenterol. , vol.10 , pp. 2954-2957
    • Zhang, Z.H.1
  • 29
    • 0032416737 scopus 로고    scopus 로고
    • Role of red meat and arachidonic acid in protein kinase C activation in rat colonic mucosa
    • Pajari,A.M. et al. (1998) Role of red meat and arachidonic acid in protein kinase C activation in rat colonic mucosa. Nutr. Cancer, 32, 86-94.
    • (1998) Nutr. Cancer , vol.32 , pp. 86-94
    • Pajari, A.M.1
  • 30
    • 58849142631 scopus 로고    scopus 로고
    • The functional -443T/C osteopontin promoter polymorphism influences osteopontin gene expression in melanoma cells via binding of c-Myb transcription factor
    • Schultz,J. et al. (2009) The functional -443T/C osteopontin promoter polymorphism influences osteopontin gene expression in melanoma cells via binding of c-yb transcription factor. Mol. Carcinog., 48, 14-23.
    • (2009) Mol. Carcinog. , vol.48 , pp. 14-23
    • Schultz, J.1
  • 31
    • 0026536323 scopus 로고
    • Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells
    • Chambers,A.F. et al. (1992) Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells. nticancer Res., 12, 43-47.
    • (1992) Anticancer Res. , vol.12 , pp. 43-47
    • Chambers, A.F.1
  • 32
    • 0036164497 scopus 로고    scopus 로고
    • Identification of the osteopontin gene as a direct target of TP53
    • Morimoto,I. et al. (2002) Identification of the osteopontin gene as a direct target of TP53. Genes Chromosomes Cancer, 33, 270-278.
    • (2002) Genes Chromosomes Cancer , vol.33 , pp. 270-278
    • Morimoto, I.1
  • 33
    • 57049166456 scopus 로고    scopus 로고
    • Osteopontin: role in immune regulation and stress responses
    • Wang,K.X. et al. (2008) Osteopontin: role in immune regulation and stress responses. Cytokine Growth Factor Rev., 19, 333-345.
    • (2008) Cytokine Growth Factor Rev. , vol.19 , pp. 333-345
    • Wang, K.X.1
  • 34
    • 77949818678 scopus 로고    scopus 로고
    • The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways
    • Courter,D. et al. (2010) The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways. PLoS One, e9633.
    • (2010) PLoS One , vol.5
    • Courter, D.1
  • 35
    • 0027076645 scopus 로고
    • Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide
    • Lee,S.H. et al. (1992) Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J. Biol. Chem., 267, 5934-25938.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25934-25938
    • Lee, S.H.1
  • 36
    • 16744362616 scopus 로고    scopus 로고
    • Osteopontin gene expression and protein synthesis in cultured rat mesangial cells
    • Nagasaki,T. et al. (1997) Osteopontin gene expression and protein synthesis in cultured rat mesangial cells. Biochem. Biophys. Res. Commun., 233, 81-85.
    • (1997) Biochem. Biophys. Res. Commun. , vol.233 , pp. 81-85
    • Nagasaki, T.1
  • 37
    • 33746173092 scopus 로고    scopus 로고
    • Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression
    • Mann,J.R. et al. (2006) Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer rogression. Cancer Res., 66, 6649-6656.
    • (2006) Cancer Res. , vol.66 , pp. 6649-6656
    • Mann, J.R.1
  • 38
    • 77955517920 scopus 로고    scopus 로고
    • Identification of genes involved in gentamicininduced nephrotoxicity in rats-a toxicogenomic investigation
    • Ozaki,N. et al. (2010) Identification of genes involved in gentamicininduced nephrotoxicity in rats-a toxicogenomic investigation. Exp. Toxicol. Pathol., 62, 55-566.
    • (2010) Exp. Toxicol. Pathol. , vol.62 , pp. 555-566
    • Ozaki, N.1
  • 39
    • 0033583818 scopus 로고    scopus 로고
    • Enhanced expression of osteopontin by high glucose in cultured rat aortic smooth muscle cells
    • Takemoto,M. et al. (1999) Enhanced expression of osteopontin by high glucose in cultured rat aortic smooth muscle cells. Biochem. Biophys. Res. Commun., 58, 722-726.
    • (1999) Biochem. Biophys. Res. Commun. , vol.258 , pp. 722-726
    • Takemoto, M.1
  • 40
    • 37149022209 scopus 로고    scopus 로고
    • Review article: the role of butyrate on colonic function
    • Hamer,H.M. et al. (2008) Review article: the role of butyrate on colonic function. Aliment. Pharmacol. Ther., 27, 104-119.
    • (2008) Aliment. Pharmacol. Ther. , vol.27 , pp. 104-119
    • Hamer, H.M.1
  • 41
    • 0036085908 scopus 로고    scopus 로고
    • Identification of genes responsive to sodium butyrate in colonic epithelial cells
    • Tabuchi,Y. et al. (2002) Identification of genes responsive to sodium butyrate in colonic epithelial cells. Biochem. Biophys. Res. Commun., 293, 1287-1294.
    • (2002) Biochem. Biophys. Res. Commun. , vol.293 , pp. 1287-1294
    • Tabuchi, Y.1
  • 42
    • 23944440915 scopus 로고    scopus 로고
    • Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications
    • Christensen,B. et al. (2005) Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications. Biochem. J., 390, 285-292.
    • (2005) Biochem. J. , vol.390 , pp. 285-292
    • Christensen, B.1
  • 43
    • 34547102777 scopus 로고    scopus 로고
    • Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties
    • Christensen,B. et al. (2007) Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties. J. Biol. hem., 282, 19463-19472.
    • (2007) J. Biol. Chem. , vol.282 , pp. 19463-19472
    • Christensen, B.1
  • 44
    • 0032533862 scopus 로고    scopus 로고
    • Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo
    • Crawford,H.C. et al. (1998) Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo. ancer Res., 58, 5206-5215.
    • (1998) Cancer Res. , vol.58 , pp. 5206-5215
    • Crawford, H.C.1
  • 45
    • 65949099324 scopus 로고    scopus 로고
    • New dualmonoclonal ELISA formeasuring plasma osteopontin as a biomarker associated with survival in prostate cancer: clinical validation and comparison of multiple ELISAs
    • Anborgh,P.H. et al. (2009) New dualmonoclonal ELISA formeasuring plasma osteopontin as a biomarker associated with survival in prostate cancer: clinical validation and comparison of multiple ELISAs. Clin. Chem., 55, 895-903.
    • (2009) Clin. Chem. , vol.55 , pp. 895-903
    • Anborgh, P.H.1
  • 46
    • 0028228866 scopus 로고
    • Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-binding domain
    • Senger,D.R. et al. (1994) Adhesive properties of osteopontin: regulation by a naturally occurring thrombin-cleavage in close proximity to the GRGDS cell-inding domain. Mol. Biol. Cell, 5, 565-574.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 565-574
    • Senger, D.R.1
  • 47
    • 77954258432 scopus 로고    scopus 로고
    • Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells
    • Sharma,P. et al. (2010) Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells. Mol. ancer, 9, 178.
    • (2010) Mol. Cancer , vol.9 , pp. 178
    • Sharma, P.1
  • 48
    • 1842531133 scopus 로고    scopus 로고
    • Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition
    • Tong,X. et al. (2004) Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition. Biochem. Biophys. Res. Commun., 317, 463-471.
    • (2004) Biochem. Biophys. Res. Commun. , vol.317 , pp. 463-471
    • Tong, X.1
  • 49
    • 2442649255 scopus 로고    scopus 로고
    • Alteration of gene expression in normal-appearing colon mucosa of APC(min) mice and human cancer patients
    • Chen,L.C. et al. (2004) Alteration of gene expression in normal-appearing colon mucosa of APC(min) mice and human cancer patients. Cancer Res., 64, 694-3700.
    • (2004) Cancer Res. , vol.64 , pp. 3694-3700
    • Chen, L.C.1
  • 50
    • 0027369679 scopus 로고
    • Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes
    • DeWitt,D.L. et al. (1993) Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes. Arch. Biochem. Biophys., 306, 94-102.
    • (1993) Arch. Biochem. Biophys. , vol.306 , pp. 94-102
    • DeWitt, D.L.1
  • 51
    • 18144381890 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulation in colon cancer cells: modulation of RNA polymerase II elongation by histone deacetylase inhibitors
    • Tong,X. et al. (2005) Cyclooxygenase-2 regulation in colon cancer cells: modulation of RNA polymerase II elongation by histone deacetylase inhibitors. J. iol. Chem., 280, 15503-15509.
    • (2005) J. Biol. Chem. , vol.280 , pp. 15503-15509
    • Tong, X.1
  • 52
    • 0042532210 scopus 로고    scopus 로고
    • Regulation of COX-2 expression in human cancers
    • Dixon,D.A. (2003) Regulation of COX-2 expression in human cancers. Prog. Exp. Tumor Res., 37, 52-71.
    • (2003) Prog. Exp. Tumor Res. , vol.37 , pp. 52-71
    • Dixon, D.A.1
  • 53
    • 42949171444 scopus 로고    scopus 로고
    • Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells
    • Usami,M. et al. (2008) Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. Nutr. Res., 28, 321-328.
    • (2008) Nutr. Res. , vol.28 , pp. 321-328
    • Usami, M.1
  • 54
    • 20644467459 scopus 로고    scopus 로고
    • Ras/MAP kinase pathways are involved in Ras specific apoptosis induced by sodium butyrate
    • Jung,J.W. et al. (2005) Ras/MAP kinase pathways are involved in Ras specific apoptosis induced by sodium butyrate. Cancer Lett., 225, 199-206.
    • (2005) Cancer Lett. , vol.225 , pp. 199-206
    • Jung, J.W.1
  • 55
    • 13544268334 scopus 로고    scopus 로고
    • 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer
    • Backlund,M.G. et al. (2005) 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. J. Biol. Chem., 280, 3217-3223.
    • (2005) J. Biol. Chem. , vol.280 , pp. 3217-3223
    • Backlund, M.G.1
  • 56
    • 33749265142 scopus 로고    scopus 로고
    • Cytoplasmic phospholipase A2 expression in human colon adenocarcinoma is correlated with cyclooxygenase-2 expression and contributes to prostaglandin E2 production
    • Panel,V. et al. (2006) Cytoplasmic phospholipase A2 expression in human colon adenocarcinoma is correlated with cyclooxygenase-2 expression and contributes to prostaglandin E2 production. Cancer Lett., 243, 255-263.
    • (2006) Cancer Lett. , vol.243 , pp. 255-263
    • Panel, V.1
  • 57
    • 67649083644 scopus 로고    scopus 로고
    • Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients
    • Seo,T. et al. (2009) Microsomal prostaglandin E synthase protein levels correlate with prognosis in colorectal cancer patients. Virchows Arch., 454, 667-676.
    • (2009) Virchows Arch , vol.454 , pp. 667-676
    • Seo, T.1
  • 58
    • 0033613852 scopus 로고    scopus 로고
    • Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic pathways
    • Murakami,M. et al. (1999) Functional coupling between various phospholipase A2s and cyclooxygenases in immediate and delayed prostanoid biosynthetic athways. J. Biol. Chem., 274, 3103-3115.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3103-3115
    • Murakami, M.1
  • 59
    • 0034692689 scopus 로고    scopus 로고
    • Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2
    • Murakami,M. et al. (2000) Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with yclooxygenase-2. J. Biol. Chem., 275, 32783-32792.
    • (2000) J. Biol. Chem. , vol.275 , pp. 32783-32792
    • Murakami, M.1
  • 60
    • 0028261042 scopus 로고
    • Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2
    • Pugh,S. et al. (1994) Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2. Gut, 35, 675-678.
    • (1994) Gut , vol.35 , pp. 675-678
    • Pugh, S.1
  • 61
    • 0037667901 scopus 로고    scopus 로고
    • Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents
    • Sherratt,P.J. et al. (2003) Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive gents. Biochem. Pharmacol., 66, 51-61.
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 51-61
    • Sherratt, P.J.1
  • 62
    • 24144488379 scopus 로고    scopus 로고
    • Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells
    • Hughes-Fulford,M. et al. (2005) Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells. Carcinogenesis, 6, 1520-1526.
    • (2005) Carcinogenesis , vol.26 , pp. 1520-1526
    • Hughes-Fulford, M.1


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