-
1
-
-
0033559933
-
Estimates of the worldwide incidence of 25 major cancers in 1990
-
Parkin DM, Pisani P, Ferlay J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer 1999;80:827-41.
-
(1999)
Int J Cancer
, vol.80
, pp. 827-841
-
-
Parkin, D.M.1
Pisani, P.2
Ferlay, J.3
-
2
-
-
0027973077
-
Molecular determinants of dysplasia in colorectal lesions
-
Jen J, Powell SM, Papadopoulos N, Smith KJ, Hamilton SR, Vogelstein B, Kinzler KW. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994;54:5523-26.
-
(1994)
Cancer Res
, vol.54
, pp. 5523-5526
-
-
Jen, J.1
Powell, S.M.2
Papadopoulos, N.3
Smith, K.J.4
Hamilton, S.R.5
Vogelstein, B.6
Kinzler, K.W.7
-
3
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B, Kinzler KW. APC mutations occur early during colorectal tumorigenesis. Nature 1992;359:235-37.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
4
-
-
0028062973
-
Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons
-
Smith AJ, Stern HS, Penner M, Hay K, Mitri A, Bapat BV, Gallinger S. Somatic APC and K-ras codon 12 mutations in aberrant crypt foci from human colons. Cancer Res 1994;54:5527-30.
-
(1994)
Cancer Res
, vol.54
, pp. 5527-5530
-
-
Smith, A.J.1
Stern, H.S.2
Penner, M.3
Hay, K.4
Mitri, A.5
Bapat, B.V.6
Gallinger, S.7
-
5
-
-
0031557898
-
The adenomatous polyposis coli (APC) tumor suppressor
-
Polakis P. The adenomatous polyposis coli (APC) tumor suppressor Biochim Biophys Acta 1997;1332:127-47.
-
(1997)
Biochim Biophys Acta
, vol.1332
, pp. 127-147
-
-
Polakis, P.1
-
6
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. Wnt signaling and cancer. Genes Dev 2000;14:1837-51.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
7
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway. Science 1998;281:1509-12.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
8
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O, McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-26.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
9
-
-
0033054464
-
The oncogenic activation of beta-catenin
-
Polakis P. The oncogenic activation of beta-catenin. Curr Opin Genet Dev 1999;9:15-21.
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 15-21
-
-
Polakis, P.1
-
10
-
-
23144462016
-
Gene expression profiles of different clinical stages of colorectal carcinoma: Toward a molecular genetic understanding of tumor progression
-
Friederichs J, Rosenberg R, Mages J, Janssen KP, Maeckl C, Nekarda H, Holzmann B, Siewert JR. Gene expression profiles of different clinical stages of colorectal carcinoma: toward a molecular genetic understanding of tumor progression. Int J Colorectal Dis 2005;20:391-402.
-
(2005)
Int J Colorectal Dis
, vol.20
, pp. 391-402
-
-
Friederichs, J.1
Rosenberg, R.2
Mages, J.3
Janssen, K.P.4
Maeckl, C.5
Nekarda, H.6
Holzmann, B.7
Siewert, J.R.8
-
11
-
-
33845465594
-
Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer
-
Rimkus C, Friederichs J, Rosenberg R, Holzmann B, Siewert JR, Janssen KP. Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer. Int J Cancer 2007;120:207-11.
-
(2007)
Int J Cancer
, vol.120
, pp. 207-211
-
-
Rimkus, C.1
Friederichs, J.2
Rosenberg, R.3
Holzmann, B.4
Siewert, J.R.5
Janssen, K.P.6
-
12
-
-
0037105704
-
Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: Differences in integrin signaling during cell adhesion to osteopontin versus vitronectin
-
Ding Q, Stewart J, Jr, Prince CW, Chang PL, Trikha M, Han X, Grammer JR, Gladson CL. Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: differences in integrin signaling during cell adhesion to osteopontin versus vitronectin. Cancer Res 2002;62:5336-43.
-
(2002)
Cancer Res
, vol.62
, pp. 5336-5343
-
-
Ding, Q.1
Stewart Jr, J.2
Prince, C.W.3
Chang, P.L.4
Trikha, M.5
Han, X.6
Grammer, J.R.7
Gladson, C.L.8
-
13
-
-
6344258588
-
The role of Osteopontin in tumor metastasis
-
Wai PY, Kuo PC. The role of Osteopontin in tumor metastasis. J Surg Res 2004;121:228-41.
-
(2004)
J Surg Res
, vol.121
, pp. 228-241
-
-
Wai, P.Y.1
Kuo, P.C.2
-
14
-
-
7044264360
-
Role of osteopontin in adhesion, migration, cell survival and bone remodeling
-
Standal T, Borset M, Sundan A. Role of osteopontin in adhesion, migration, cell survival and bone remodeling. Exp Oncol 2004;26:179-84.
-
(2004)
Exp Oncol
, vol.26
, pp. 179-184
-
-
Standal, T.1
Borset, M.2
Sundan, A.3
-
15
-
-
12544255790
-
Osteopontin regulates multiple functions contributing to human colon cancer development and progression
-
Irby RB, McCarthy SM, Yeatman TJ. Osteopontin regulates multiple functions contributing to human colon cancer development and progression. Clin Exp Metastasis 2004;21:515-23.
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 515-523
-
-
Irby, R.B.1
McCarthy, S.M.2
Yeatman, T.J.3
-
16
-
-
33746825450
-
Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation
-
Wai PY, Guo L, Gao C, Mi Z, Guo H, Kuo PC. Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation. Surgery 2006;140:132-40.
-
(2006)
Surgery
, vol.140
, pp. 132-140
-
-
Wai, P.Y.1
Guo, L.2
Gao, C.3
Mi, Z.4
Guo, H.5
Kuo, P.C.6
-
17
-
-
0037012338
-
Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling
-
Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, Cantor A, Coppola D, Yeatman TJ. Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. J Natl Cancer Inst 2002;94:513-21.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 513-521
-
-
Agrawal, D.1
Chen, T.2
Irby, R.3
Quackenbush, J.4
Chambers, A.F.5
Szabo, M.6
Cantor, A.7
Coppola, D.8
Yeatman, T.J.9
-
18
-
-
0345860905
-
Osteopontin identified as colon cancer tumor progression marker
-
Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, Cantor A, Coppola D, Yeatman TJ. Osteopontin identified as colon cancer tumor progression marker. C R Biol 2003;326:1041-43.
-
(2003)
C R Biol
, vol.326
, pp. 1041-1043
-
-
Agrawal, D.1
Chen, T.2
Irby, R.3
Quackenbush, J.4
Chambers, A.F.5
Szabo, M.6
Cantor, A.7
Coppola, D.8
Yeatman, T.J.9
-
20
-
-
20644443287
-
Molecular staging for survival prediction of colorectal cancer patients
-
Eschrich S, Yang I, Bloom G, Kwong KY, Boulware D, Cantor A, Coppola D, Kruhoffer M, Aaltonen L, Orntoft TF, Quackenbush J, Yeatman TJ. Molecular staging for survival prediction of colorectal cancer patients. J Clin Oncol 2005;23:3526-35.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3526-3535
-
-
Eschrich, S.1
Yang, I.2
Bloom, G.3
Kwong, K.Y.4
Boulware, D.5
Cantor, A.6
Coppola, D.7
Kruhoffer, M.8
Aaltonen, L.9
Orntoft, T.F.10
Quackenbush, J.11
Yeatman, T.J.12
-
21
-
-
0035967101
-
Regulatory region of metastasis-inducing DNA is the binding site for T cell factor-4
-
El Tanani MK, Barraclough R, Wilkinson MC, Rudland PS. Regulatory region of metastasis-inducing DNA is the binding site for T cell factor-4. Oncogene 2001;20:1793-97.
-
(2001)
Oncogene
, vol.20
, pp. 1793-1797
-
-
El Tanani, M.K.1
Barraclough, R.2
Wilkinson, M.C.3
Rudland, P.S.4
-
22
-
-
0035671826
-
Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer
-
Fedarko NS, Jain A, Karadag A, Van Eman MR, Fisher LW. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin Cancer Res 2001;7:4060-66.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 4060-4066
-
-
Fedarko, N.S.1
Jain, A.2
Karadag, A.3
Van Eman, M.R.4
Fisher, L.W.5
-
23
-
-
33748371845
-
Elevated Plasma Osteopontin Levels in Patients with Hepatocellular Carcinoma
-
Kim J, Ki SS, Lee SD, Han CJ, Kim YC, Park SH, Cho SY, Hong YJ, Park HY, Lee M, Jung HH, Lee KH, Jeong SH. Elevated Plasma Osteopontin Levels in Patients with Hepatocellular Carcinoma. Am J Gastroenterol 2006;101:2051-59.
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 2051-2059
-
-
Kim, J.1
Ki, S.S.2
Lee, S.D.3
Han, C.J.4
Kim, Y.C.5
Park, S.H.6
Cho, S.Y.7
Hong, Y.J.8
Park, H.Y.9
Lee, M.10
Jung, H.H.11
Lee, K.H.12
Jeong, S.H.13
-
24
-
-
0030988805
-
Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival
-
Singhal H, Bautista DS, Tonkin KS, O'Malley FP, Tuck AB, Chambers AF, Harris JF. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. Clin Cancer Res 1997;3:605-11.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 605-611
-
-
Singhal, H.1
Bautista, D.S.2
Tonkin, K.S.3
O'Malley, F.P.4
Tuck, A.B.5
Chambers, A.F.6
Harris, J.F.7
-
25
-
-
0028567875
-
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde R, Edelmann W, Yang K, van Leeuwen C, Carlson C, Renault B, Breukel C, Alt E, Lipkin M, Khan PM, et al. A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci USA 1994;91:8969-73.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
Edelmann, W.2
Yang, K.3
van Leeuwen, C.4
Carlson, C.5
Renault, B.6
Breukel, C.7
Alt, E.8
Lipkin, M.9
Khan, P.M.10
-
26
-
-
0036328995
-
Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice
-
Janssen K-P, Marjou FE, Pinto D, Sastre X, Rouillard D, Fouquet C, Soussi T, Louvard D, Robine S. Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice. Gastroenterology 2002;123:492-504.
-
(2002)
Gastroenterology
, vol.123
, pp. 492-504
-
-
Janssen, K.-P.1
Marjou, F.E.2
Pinto, D.3
Sastre, X.4
Rouillard, D.5
Fouquet, C.6
Soussi, T.7
Louvard, D.8
Robine, S.9
-
27
-
-
2342603414
-
Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis
-
Zhu P, Martin E, Mengwasser J, Schlag P, Janssen KP, Gottlicher M. Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis. Cancer Cell 2004;5:455-63.
-
(2004)
Cancer Cell
, vol.5
, pp. 455-463
-
-
Zhu, P.1
Martin, E.2
Mengwasser, J.3
Schlag, P.4
Janssen, K.P.5
Gottlicher, M.6
-
28
-
-
18644373146
-
The beta-catenin/TCF4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
-
van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, van der Horn K, Batlle E, Coudreuse D, Haramis AP, Tjon-Pon-Fong M, Moerer P, et al. The beta-catenin/TCF4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002;111:241-50.
-
(2002)
Cell
, vol.111
, pp. 241-250
-
-
van de Wetering, M.1
Sancho, E.2
Verweij, C.3
de Lau, W.4
Oving, I.5
Hurlstone, A.6
van der Horn, K.7
Batlle, E.8
Coudreuse, D.9
Haramis, A.P.10
Tjon-Pon-Fong, M.11
Moerer, P.12
-
29
-
-
0035021027
-
Osteopontin as a means to cope with environmental insults: Regulation of inflammation, tissue remodeling, and cell survival
-
Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS. Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 2001;107:1055-61.
-
(2001)
J Clin Invest
, vol.107
, pp. 1055-1061
-
-
Denhardt, D.T.1
Noda, M.2
O'Regan, A.W.3
Pavlin, D.4
Berman, J.S.5
-
30
-
-
0035524455
-
The functional and clinical roles of osteopontin in cancer and metastasis
-
Furger KA, Menon RK, Tuck AB, Bramwell VH, Chambers AF. The functional and clinical roles of osteopontin in cancer and metastasis. Curr Mol Med 2001;1:621-32.
-
(2001)
Curr Mol Med
, vol.1
, pp. 621-632
-
-
Furger, K.A.1
Menon, R.K.2
Tuck, A.B.3
Bramwell, V.H.4
Chambers, A.F.5
-
31
-
-
0037468265
-
Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways
-
Tuck AB, Hota C, Wilson SM, Chambers AF. Osteopontin-induced migration of human mammary epithelial cells involves activation of EGF receptor and multiple signal transduction pathways. Oncogene 2003;22:1198-205.
-
(2003)
Oncogene
, vol.22
, pp. 1198-1205
-
-
Tuck, A.B.1
Hota, C.2
Wilson, S.M.3
Chambers, A.F.4
-
32
-
-
0035495596
-
The role of osteopontin in breast cancer: Clinical and experimental studies
-
Tuck AB, Chambers AF. The role of osteopontin in breast cancer: clinical and experimental studies. J Mammary Gland Biol Neoplasia 2001;6:419-29.
-
(2001)
J Mammary Gland Biol Neoplasia
, vol.6
, pp. 419-429
-
-
Tuck, A.B.1
Chambers, A.F.2
-
33
-
-
0037012469
-
Osteopontin as a potential diagnostic biomarker for ovarian cancer
-
Kim JH, Skates SJ, Uede T, Wong KK, Schorge JO, Feltmate CM, Berkowitz RS, Cramer DW, Mok SC. Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA 2002;287:1671-79.
-
(2002)
JAMA
, vol.287
, pp. 1671-1679
-
-
Kim, J.H.1
Skates, S.J.2
Uede, T.3
Wong, K.K.4
Schorge, J.O.5
Feltmate, C.M.6
Berkowitz, R.S.7
Cramer, D.W.8
Mok, S.C.9
-
34
-
-
2442635516
-
Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma
-
Koopmann J, Fedarko NS, Jain A, Maitra A, Iacobuzio-Donahue C, Rahman A, Hruban RH, Yeo CJ, Goggins M. Evaluation of osteopontin as biomarker for pancreatic adenocarcinoma. Cancer Epidemiol Biomarkers Prev 2004;13:487-91.
-
(2004)
Cancer Epidemiol Biomarkers Prev
, vol.13
, pp. 487-491
-
-
Koopmann, J.1
Fedarko, N.S.2
Jain, A.3
Maitra, A.4
Iacobuzio-Donahue, C.5
Rahman, A.6
Hruban, R.H.7
Yeo, C.J.8
Goggins, M.9
-
35
-
-
0032837577
-
Beta-catenin expression in primary and metastatic colorectal carcinoma
-
Hugh TJ, Dillon SA, O'Dowd G, Getty B, Pignatelli M, Poston GJ, Kinsella AR. Beta-catenin expression in primary and metastatic colorectal carcinoma. Int J Cancer 1999;82:504-11.
-
(1999)
Int J Cancer
, vol.82
, pp. 504-511
-
-
Hugh, T.J.1
Dillon, S.A.2
O'Dowd, G.3
Getty, B.4
Pignatelli, M.5
Poston, G.J.6
Kinsella, A.R.7
-
36
-
-
28844484951
-
TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase- dependent
-
Vietor I, Kurzbauer R, Brosch G, Huber LA. TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase- dependent. J Biol Chem 2005;280:39795-801.
-
(2005)
J Biol Chem
, vol.280
, pp. 39795-39801
-
-
Vietor, I.1
Kurzbauer, R.2
Brosch, G.3
Huber, L.A.4
-
37
-
-
0033804719
-
Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity
-
Smits R, Hofland N, Edelmann W, Geugien M, Jagmohan-Changur S, Albuquerque C, Breukel C, Kucherlapati R, Kielman MF, Fodde R. Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity. Genes Chromosomes Cancer 2000;29:229-39.
-
(2000)
Genes Chromosomes Cancer
, vol.29
, pp. 229-239
-
-
Smits, R.1
Hofland, N.2
Edelmann, W.3
Geugien, M.4
Jagmohan-Changur, S.5
Albuquerque, C.6
Breukel, C.7
Kucherlapati, R.8
Kielman, M.F.9
Fodde, R.10
-
38
-
-
0037220080
-
Transcriptional regulation of OPN and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter
-
Denhardt DT, Mistretta D, Chambers AF, Krishna S, Porter JF, Raghuram S, Rittling SR. Transcriptional regulation of OPN and the metastatic phenotype: evidence for a Ras-activated enhancer in the human OPN promoter. Clin Exp Metastasis 2003;20:77-84.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 77-84
-
-
Denhardt, D.T.1
Mistretta, D.2
Chambers, A.F.3
Krishna, S.4
Porter, J.F.5
Raghuram, S.6
Rittling, S.R.7
|