메뉴 건너뛰기




Volumn 20, Issue 6, 2011, Pages 827-840

SLIT/ROBO1 signaling suppresses mammary branching morphogenesis by limiting basal cell number

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; SLIT PROTEIN; SLIT2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; WNT PROTEIN;

EID: 79958189228     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2011.05.012     Document Type: Article
Times cited : (86)

References (54)
  • 1
    • 77951224719 scopus 로고    scopus 로고
    • Morphogenesis of epithelial tubes: insights into tube formation, elongation, and elaboration
    • Andrew D.J., Ewald A.J. Morphogenesis of epithelial tubes: insights into tube formation, elongation, and elaboration. Dev. Biol. 2010, 341:34-55.
    • (2010) Dev. Biol. , vol.341 , pp. 34-55
    • Andrew, D.J.1    Ewald, A.J.2
  • 4
    • 33645339525 scopus 로고    scopus 로고
    • Mechanisms of disease: breast tumor pathogenesis and the role of the myoepithelial cell
    • Barsky S.H., Karlin N.J. Mechanisms of disease: breast tumor pathogenesis and the role of the myoepithelial cell. Nat. Clin. Pract. Oncol. 2006, 3:138-151.
    • (2006) Nat. Clin. Pract. Oncol. , vol.3 , pp. 138-151
    • Barsky, S.H.1    Karlin, N.J.2
  • 5
    • 84981758100 scopus 로고
    • Topography of DNA synthesis in the mammary gland of the CH3 mouse and its control by ovarian hormones: an autoradiographic study
    • Bresciani F. Topography of DNA synthesis in the mammary gland of the CH3 mouse and its control by ovarian hormones: an autoradiographic study. Cell Tissue Kinet. 1968, 1:51-63.
    • (1968) Cell Tissue Kinet. , vol.1 , pp. 51-63
    • Bresciani, F.1
  • 6
    • 0033582914 scopus 로고    scopus 로고
    • Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
    • Brose K., Bland K.S., Wang K.H., Arnott D., Henzel W., Goodman C.S., Tessier-Lavigne M., Kidd T. Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell 1999, 96:795-806.
    • (1999) Cell , vol.96 , pp. 795-806
    • Brose, K.1    Bland, K.S.2    Wang, K.H.3    Arnott, D.4    Henzel, W.5    Goodman, C.S.6    Tessier-Lavigne, M.7    Kidd, T.8
  • 7
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross D.A., Alessi D.R., Cohen P., Andjelkovich M., Hemmings B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995, 378:785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 8
    • 53249106397 scopus 로고    scopus 로고
    • Epigenetic disruption of the SLIT-ROBO interactions in human cancer
    • Springer Netherlands, New York, R.J. Ablin, W.G. Jiang, M. Esteller (Eds.)
    • Dallol A., Dickinson R.E., Latif F. Epigenetic disruption of the SLIT-ROBO interactions in human cancer. DNA Methylation, Epigenetics and Metastasis 2005, 191-214. Springer Netherlands, New York. R.J. Ablin, W.G. Jiang, M. Esteller (Eds.).
    • (2005) DNA Methylation, Epigenetics and Metastasis , pp. 191-214
    • Dallol, A.1    Dickinson, R.E.2    Latif, F.3
  • 10
    • 41649121862 scopus 로고    scopus 로고
    • Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis
    • Ewald A.J., Brenot A., Duong M., Chan B.S., Werb Z. Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev. Cell 2008, 14:570-581.
    • (2008) Dev. Cell , vol.14 , pp. 570-581
    • Ewald, A.J.1    Brenot, A.2    Duong, M.3    Chan, B.S.4    Werb, Z.5
  • 11
    • 0036081239 scopus 로고    scopus 로고
    • Latent transforming growth factor-β activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation
    • Ewan K.B., Shyamala G., Ravani S.A., Tang Y., Akhurst R., Wakefield L., Barcellos-Hoff M.H. Latent transforming growth factor-β activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation. Am. J. Pathol. 2002, 160:2081-2093.
    • (2002) Am. J. Pathol. , vol.160 , pp. 2081-2093
    • Ewan, K.B.1    Shyamala, G.2    Ravani, S.A.3    Tang, Y.4    Akhurst, R.5    Wakefield, L.6    Barcellos-Hoff, M.H.7
  • 16
    • 67549107230 scopus 로고    scopus 로고
    • Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression
    • Holliday D.L., Brouilette K.T., Markert A., Gordon L.A., Jones J.L. Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression. Breast Cancer Res. 2009, 11:R3.
    • (2009) Breast Cancer Res. , vol.11
    • Holliday, D.L.1    Brouilette, K.T.2    Markert, A.3    Gordon, L.A.4    Jones, J.L.5
  • 17
    • 0041970961 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression, β-catenin tyrosine phosphorylation, and endothelial proliferative behavior: a pathway for transformation?
    • Ilan N., Tucker A., Madri J.A. Vascular endothelial growth factor expression, β-catenin tyrosine phosphorylation, and endothelial proliferative behavior: a pathway for transformation?. Lab. Invest. 2003, 83:1105-1115.
    • (2003) Lab. Invest. , vol.83 , pp. 1105-1115
    • Ilan, N.1    Tucker, A.2    Madri, J.A.3
  • 18
    • 53349129756 scopus 로고    scopus 로고
    • Mammary gland development in transforming growth factor β1 null mutant mice: systemic and epithelial effects
    • Ingman W.V., Robertson S.A. Mammary gland development in transforming growth factor β1 null mutant mice: systemic and epithelial effects. Biol. Reprod. 2008, 79:711-717.
    • (2008) Biol. Reprod. , vol.79 , pp. 711-717
    • Ingman, W.V.1    Robertson, S.A.2
  • 22
    • 33751235462 scopus 로고    scopus 로고
    • Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis
    • Kouros-Mehr H., Werb Z. Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis. Dev. Dyn. 2006, 235:3404-3412.
    • (2006) Dev. Dyn. , vol.235 , pp. 3404-3412
    • Kouros-Mehr, H.1    Werb, Z.2
  • 23
    • 33846456632 scopus 로고    scopus 로고
    • Transcriptional cooperation between the transforming growth factor-β and Wnt pathways in mammary and intestinal tumorigenesis
    • Labbe E., Lock L., Letamendia A., Gorska A.E., Gryfe R., Gallinger S., Moses H.L., Attisano L. Transcriptional cooperation between the transforming growth factor-β and Wnt pathways in mammary and intestinal tumorigenesis. Cancer Res. 2007, 67:75-84.
    • (2007) Cancer Res. , vol.67 , pp. 75-84
    • Labbe, E.1    Lock, L.2    Letamendia, A.3    Gorska, A.E.4    Gryfe, R.5    Gallinger, S.6    Moses, H.L.7    Attisano, L.8
  • 24
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • Lee G.Y., Kenny P.A., Lee E.H., Bissell M.J. Three-dimensional culture models of normal and malignant breast epithelial cells. Nat. Methods 2007, 4:359-365.
    • (2007) Nat. Methods , vol.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4
  • 25
    • 33845941448 scopus 로고    scopus 로고
    • The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis
    • Lindvall C., Evans N.C., Zylstra C.R., Li Y., Alexander C.M., Williams B.O. The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis. J. Biol. Chem. 2006, 281:35081-35087.
    • (2006) J. Biol. Chem. , vol.281 , pp. 35081-35087
    • Lindvall, C.1    Evans, N.C.2    Zylstra, C.R.3    Li, Y.4    Alexander, C.M.5    Williams, B.O.6
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method. Methods 2001, 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 29
    • 49049096654 scopus 로고    scopus 로고
    • Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis
    • Lu P., Ewald A.J., Martin G.R., Werb Z. Genetic mosaic analysis reveals FGF receptor 2 function in terminal end buds during mammary gland branching morphogenesis. Dev. Biol. 2008, 321:77-87.
    • (2008) Dev. Biol. , vol.321 , pp. 77-87
    • Lu, P.1    Ewald, A.J.2    Martin, G.R.3    Werb, Z.4
  • 33
    • 9644274187 scopus 로고    scopus 로고
    • Integrity of cell-cell contacts is a critical regulator of TGF-β1-induced epithelial-to-myofibroblast transition: role for β-catenin
    • Masszi A., Fan L., Rosivall L., McCulloch C.A., Rotstein O.D., Mucsi I., Kapus A. Integrity of cell-cell contacts is a critical regulator of TGF-β1-induced epithelial-to-myofibroblast transition: role for β-catenin. Am. J. Pathol. 2004, 165:1955-1967.
    • (2004) Am. J. Pathol. , vol.165 , pp. 1955-1967
    • Masszi, A.1    Fan, L.2    Rosivall, L.3    McCulloch, C.A.4    Rotstein, O.D.5    Mucsi, I.6    Kapus, A.7
  • 34
    • 33646596637 scopus 로고    scopus 로고
    • Cooperation between Snail and LEF-1 transcription factors is essential for TGF-β1-induced epithelial-mesenchymal transition
    • Medici D., Hay E.D., Goodenough D.A. Cooperation between Snail and LEF-1 transcription factors is essential for TGF-β1-induced epithelial-mesenchymal transition. Mol. Biol. Cell 2006, 17:1871-1879.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 1871-1879
    • Medici, D.1    Hay, E.D.2    Goodenough, D.A.3
  • 35
    • 33749992857 scopus 로고    scopus 로고
    • Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures
    • Nelson C.M., Vanduijn M.M., Inman J.L., Fletcher D.A., Bissell M.J. Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures. Science 2006, 314:298-300.
    • (2006) Science , vol.314 , pp. 298-300
    • Nelson, C.M.1    Vanduijn, M.M.2    Inman, J.L.3    Fletcher, D.A.4    Bissell, M.J.5
  • 37
    • 79958228344 scopus 로고    scopus 로고
    • Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture
    • in press. Published online April 1, 2011
    • Pavlovich A.L., Boghaert E., Nelson C.M. Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture. Exp. Cell Res. 2011, in press. Published online April 1, 2011. 10.1016/j.yexcr.2011.03.017.
    • (2011) Exp. Cell Res.
    • Pavlovich, A.L.1    Boghaert, E.2    Nelson, C.M.3
  • 38
    • 55549115695 scopus 로고    scopus 로고
    • Slit-2 induces a tumor-suppressive effect by regulating β-catenin in breast cancer cells
    • Prasad A., Paruchuri V., Preet A., Latif F., Ganju R.K. Slit-2 induces a tumor-suppressive effect by regulating β-catenin in breast cancer cells. J. Biol. Chem. 2008, 283:26624-26633.
    • (2008) J. Biol. Chem. , vol.283 , pp. 26624-26633
    • Prasad, A.1    Paruchuri, V.2    Preet, A.3    Latif, F.4    Ganju, R.K.5
  • 39
    • 36549025433 scopus 로고    scopus 로고
    • Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growth
    • Roarty K., Serra R. Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growth. Development 2007, 134:3929-3939.
    • (2007) Development , vol.134 , pp. 3929-3939
    • Roarty, K.1    Serra, R.2
  • 40
    • 68349123821 scopus 로고    scopus 로고
    • Loss of TGF-β or Wnt5a results in an increase in Wnt/β-catenin activity and redirects mammary tumour phenotype
    • Roarty K., Baxley S.E., Crowley M.R., Frost A.R., Serra R. Loss of TGF-β or Wnt5a results in an increase in Wnt/β-catenin activity and redirects mammary tumour phenotype. Breast Cancer Res. 2009, 11:R19.
    • (2009) Breast Cancer Res. , vol.11
    • Roarty, K.1    Baxley, S.E.2    Crowley, M.R.3    Frost, A.R.4    Serra, R.5
  • 42
    • 0035863007 scopus 로고    scopus 로고
    • Postnatal mammary gland morphogenesis
    • Silberstein G.B. Postnatal mammary gland morphogenesis. Microsc. Res. Tech. 2001, 52:155-162.
    • (2001) Microsc. Res. Tech. , vol.52 , pp. 155-162
    • Silberstein, G.B.1
  • 43
    • 0023409387 scopus 로고
    • Investigation of mouse mammary ductal growth regulation using slow-release plastic implants
    • Silberstein G.B., Daniel C.W. Investigation of mouse mammary ductal growth regulation using slow-release plastic implants. J. Dairy Sci. 1987, 70:1981-1990.
    • (1987) J. Dairy Sci. , vol.70 , pp. 1981-1990
    • Silberstein, G.B.1    Daniel, C.W.2
  • 44
    • 0036166297 scopus 로고    scopus 로고
    • Wnt signals are transmitted through N-terminally dephosphorylated β-catenin
    • Staal F.J., van Noort M., Strous G.J., Clevers H.C. Wnt signals are transmitted through N-terminally dephosphorylated β-catenin. EMBO Rep. 2002, 3:63-68.
    • (2002) EMBO Rep. , vol.3 , pp. 63-68
    • Staal, F.J.1    van Noort, M.2    Strous, G.J.3    Clevers, H.C.4
  • 46
    • 33645536314 scopus 로고    scopus 로고
    • Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis
    • Strickland P., Shin G.C., Plump A., Tessier-Lavigne M., Hinck L. Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis. Development 2006, 133:823-832.
    • (2006) Development , vol.133 , pp. 823-832
    • Strickland, P.1    Shin, G.C.2    Plump, A.3    Tessier-Lavigne, M.4    Hinck, L.5
  • 47
    • 13944259795 scopus 로고    scopus 로고
    • Targeted activation of β-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia
    • Teuliere J., Faraldo M.M., Deugnier M.A., Shtutman M., Ben-Ze'ev A., Thiery J.P., Glukhova M.A. Targeted activation of β-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia. Development 2005, 132:267-277.
    • (2005) Development , vol.132 , pp. 267-277
    • Teuliere, J.1    Faraldo, M.M.2    Deugnier, M.A.3    Shtutman, M.4    Ben-Ze'ev, A.5    Thiery, J.P.6    Glukhova, M.A.7
  • 48
    • 76549117409 scopus 로고    scopus 로고
    • SLIT2 attenuation during lung cancer progression deregulates β-catenin and E-cadherin and associates with poor prognosis
    • Tseng R.C., Lee S.H., Hsu H.S., Chen B.H., Tsai W.C., Tzao C., Wang Y.C. SLIT2 attenuation during lung cancer progression deregulates β-catenin and E-cadherin and associates with poor prognosis. Cancer Res. 2010, 70:543-551.
    • (2010) Cancer Res. , vol.70 , pp. 543-551
    • Tseng, R.C.1    Lee, S.H.2    Hsu, H.S.3    Chen, B.H.4    Tsai, W.C.5    Tzao, C.6    Wang, Y.C.7
  • 49
    • 0033582915 scopus 로고    scopus 로고
    • Biochemical purification of a mammalian Slit protein as a positive regulator of sensory axon elongation and branching
    • Wang K.H., Brose K., Arnott D., Kidd T., Goodman C.S., Henzel W., Tessier-Lavigne M. Biochemical purification of a mammalian Slit protein as a positive regulator of sensory axon elongation and branching. Cell 1999, 96:771-784.
    • (1999) Cell , vol.96 , pp. 771-784
    • Wang, K.H.1    Brose, K.2    Arnott, D.3    Kidd, T.4    Goodman, C.S.5    Henzel, W.6    Tessier-Lavigne, M.7
  • 50
    • 0020627016 scopus 로고
    • Mammary ductal elongation: differentiation of myoepithelium and basal lamina during branching morphogenesis
    • Williams J.M., Daniel C.W. Mammary ductal elongation: differentiation of myoepithelium and basal lamina during branching morphogenesis. Dev. Biol. 1983, 97:274-290.
    • (1983) Dev. Biol. , vol.97 , pp. 274-290
    • Williams, J.M.1    Daniel, C.W.2
  • 51
  • 52
    • 77953065143 scopus 로고    scopus 로고
    • Moving away from the midline: new developments for Slit and Robo
    • Ypsilanti A.R., Zagar Y., Chedotal A. Moving away from the midline: new developments for Slit and Robo. Development 2010, 137:1939-1952.
    • (2010) Development , vol.137 , pp. 1939-1952
    • Ypsilanti, A.R.1    Zagar, Y.2    Chedotal, A.3
  • 53
    • 0035156083 scopus 로고    scopus 로고
    • Transforming growth factor-β signal transduction in epithelial cells
    • Yue J., Mulder K.M. Transforming growth factor-β signal transduction in epithelial cells. Pharmacol. Ther. 2001, 91:1-34.
    • (2001) Pharmacol. Ther. , vol.91 , pp. 1-34
    • Yue, J.1    Mulder, K.M.2
  • 54
    • 77956628008 scopus 로고    scopus 로고
    • Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture
    • Zeng Y.A., Nusse R. Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture. Cell Stem Cell 2010, 6:568-577.
    • (2010) Cell Stem Cell , vol.6 , pp. 568-577
    • Zeng, Y.A.1    Nusse, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.