Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling

Developmental Biology

Volumn 317, Issue 1, 2008, Pages 121-131

  Parsa, Sara ^a,b   Ramasamy, Suresh K ^a   De Langhe, Stijn ^a   Gupte, Varsha V ^a   Haigh, Jody J ^c   Medina, Daniel ^d   Bellusci, Savério ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c GHENT UNIVERSITY   (Belgium)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Branching; Ductal epithelium; Fgf10; Fgfr2b; Post natal mammary gland development; Proliferation; Terminal end buds

Indexed keywords

FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 2B; TETRACYCLINE; TRANSCRIPTION FACTOR GLI3;

ADIPOSE TISSUE; ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRANCHING MORPHOGENESIS; BREAST DEVELOPMENT; BREAST EPITHELIUM; CELL PROLIFERATION; CELL REGENERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO AXIS; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; FEMALE; MOUSE; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TISSUE TRANSPLANTATION;

ANIMALIA; MUS;

EID: 42649087404     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2008.02.014     Document Type: Article

References (35)

1. T. Asaki M. Konishi A. Miyake S. Kato M. Tomizawa N. Itoh Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo Mol. Cell. Endocrinol. 218 2004 119 128
2. G. Belteki J. Haigh N. Kabacs K. Haigh K. Sison F. Costantini J. Whitsett S.E. Quaggin A. Nagy Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction Nucleic Acids Res. 33 2005 e51
3. W.P. Bocchinfuso J.K. Lindzey S.C. Hewitt J.A. Clark P.H. Myers R. Cooper K.S. Korach Induction of mammary gland development in estrogen receptor-knockout mice Endocrinology 141 2000 2982 2994
4. S.P. De Langhe F.G. Sala P.M. Del Moral T.J. Fairbanks K.M. Yamada D. Warburton R.C. Burns S. Bellusci Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung Dev. Biol. 277 2005 316 331
5. L. De Moerlooze B. Spencer-Dene J. Revest M. Hajihosseini I. Rosewell C. Dickson An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal–epithelial signalling during mouse organogenesis Development 127 2000 483 492
6. M.M. Faraldo M.A. Deugnier M. Lukashev J.P. Thiery M.A. Glukhova Perturbation of beta1-integrin function alters the development of murine mammary gland EMBO J. 17 1998 2139 2147
7. Y. Feng D. Manka K.U. Wagner S.A. Khan Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice Proc. Natl. Acad. Sci. U. S. A. 104 37 2007 14718 14723
8. M. Gossen H. Bujard Tight control of gene expression in mammalian cells by tetracycline-responsive promoters Proc. Natl. Acad. Sci. U. S. A. 89 1992 5547 5551
9. R. Grose C. Dickson Fibroblast growth factor signaling in tumorigenesis Cytokine Growth Factor Rev. 16 2005 179 186
10. H. Harada T. Toyono K. Toyoshima M. Yamasaki N. Itoh S. Kato K. Sekine H. Ohuchi FGF10 maintains stem cell compartment in developing mouse incisors Development 129 2002 1533 1541
11. I. Hokuto A.K. Perl J.A. Whitsett Prenatal, but not postnatal, inhibition of fibroblast growth factor receptor signaling causes emphysema J. Biol. Chem. 278 2003 415 421
12. D.J. Hunter P. Kraft K.B. Jacobs D.G. Cox M. Yeager S.E. Hankinson S. Wacholder Z. Wang R. Welch A. Hutchinson J. Wang K. Yu N. Chatterjee N. Orr W.C. Willett G.A. Colditz R.G. Ziegler C.D. Berg S.S. Buys C.A. McCarty H.S. Feigelson E.E. Calle M.J. Thun R.B. Hayes M. Tucker D.S. Gerhard J.F. Fraumeni Jr. R.N. Hoover G. Thomas S.J. Chanock A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer Nat. Genet. 39 2007 870 874
13. R. Kelly S. Alonso S. Tajbakhsh G. Cossu M. Buckingham Myosin light chain 3F regulatory sequences confer regionalized cardiac and skeletal muscle expression in transgenic mice J. Cell Biol. 129 1995 383 396
14. R.G. Kelly N.A. Brown M.E. Buckingham The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm Dev. Cell 1 2001 435 440
15. K.S. Korach J.F. Couse S.W. Curtis T.F. Washburn J. Lindzey K.S. Kimbro E.M. Eddy S. Migliaccio S.M. Snedeker D.B. Lubahn D.W. Schomberg E.P. Smith Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes Recent Prog. Horm. Res. 51 1996 159 188
16. Y. Lin G. Liu Y. Zhang Y.P. Hu K. Yu C. Lin K. McKeehan J.W. Xuan D.M. Ornitz M.M. Shen N. Greenberg W.L. McKeehan F. Wang Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis Development 134 2007 723 734
17. A.A. Mailleux B. Spencer-Dene C. Dillon D. Ndiaye C. Savona-Baron N. Itoh S. Kato C. Dickson J.P. Thiery S. Bellusci Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo Development 129 2002 53 60
18. A.A. Mailleux R. Kelly J.M. Veltmaat S.P. De Langhe S. Zaffran J.P. Thiery S. Bellusci Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage Development 132 2005 2157 2166
19. D. Medina The mammary gland: a unique organ for the study of development and tumorigenesis J. Mammary Gland Biol. Neoplasia 1 1996 5 19
20. A.B. Moffa S.P. Ethier Differential signal transduction of alternatively spliced FGFR2 variants expressed in human mammary epithelial cells J. Cell. Physiol. 210 2007 720 731
21. V.K. Pedchenko W. Imagawa Pattern of expression of the KGF receptor and its ligands KGF and FGF-10 during postnatal mouse mammary gland development Mol. Reprod. Dev. 56 2000 441 447
22. H. Sakaue M. Konishi W. Ogawa T. Asaki T. Mori M. Yamasaki M. Takata H. Ueno S. Kato M. Kasuga N. Itoh Requirement of fibroblast growth factor 10 in development of white adipose tissue Genes Dev. 16 2002 908 912
23. F.G. Sala J.L. Curtis J.M. Veltmaat P.M. Del Moral L.T. Le T.J. Fairbanks D. Warburton H. Ford K. Wang R.C. Burns S. Bellusci Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development Dev. Biol. 299 2006 373 385
24. T. Schlake FGF signals specifically regulate the structure of hair shaft medulla via IGF-binding protein 5 Development 132 2005 2981 2990
25. F. Schwenk U. Baron K. Rajewsky A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells Nucleic Acids Res. 23 1995 5080 5081
26. K. Sekine H. Ohuchi M. Fujiwara M. Yamasaki T. Yoshizawa T. Sato N. Yagishita D. Matsui Y. Koga N. Itoh S. Kato Fgf10 is essential for limb and lung formation Nat. Genet. 21 1999 138 141
27. M.D. Sternlicht H. Kouros-Mehr P. Lu Z. Werb Hormonal and local control of mammary branching morphogenesis Differentiation 74 2006 365 381
28. V. Theodorou M. Boer B. Weigelt J. Jonkers M. van der Valk J. Hilkens Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas Oncogene 23 2004 6047 6055
29. J.M. Veltmaat A.A. Mailleux J.P. Thiery S. Bellusci Mouse embryonic mammogenesis as a model for the molecular regulation of pattern formation Differentiation 71 2003 1 17
30. J.M. Veltmaat W. Van Veelen J.P. Thiery S. Bellusci Identification of the mammary line in mouse by Wnt10b expression Dev. Dyn. 229 2004 349 356
31. J.M. Veltmaat F. Relaix L.T. Le K. Kratochwil F.G. Sala W. van Veelen R. Rice B. Spencer-Dene A.A. Mailleux D.P. Rice J.P. Thiery S. Bellusci Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes Development 133 2006 2325 2335
32. B.S. Wiseman Z. Werb Stromal effects on mammary gland development and breast cancer Science 296 2002 1046 1049
33. M. Yamasaki H. Emoto M. Konishi T. Mikami H. Ohuchi K. Nakao N. Itoh FGF-10 is a growth factor for preadipocytes in white adipose tissue Biochem. Biophys. Res. Commun. 258 1999 109 112
34. T. Yokohama-Tamaki H. Ohshima N. Fujiwara Y. Takada Y. Ichimori S. Wakisaka H. Ohuchi H. Harada Cessation of Fgf10 signaling, resulting in a defective dental epithelial stem cell compartment, leads to the transition from crown to root formation Development 133 2006 1359 1366
35. B.P. Zambrowicz A. Imamoto S. Fiering L.A. Herzenberg W.G. Kerr P. Soriano Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells Proc. Natl. Acad. Sci. U. S. A. 94 1997 3789 3794