The tyrosine kinase inhibitor sorafenib sensitizes hepatocellular carcinoma cells to taxol by suppressing the HURP protein

Biochemical Pharmacology

Volumn 82, Issue 2, 2011, Pages 184-194

  Kuo, Tzu Ching ^a   Lu, Hsing Pang ^a   Chao, Chuck C K ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Hepatocellular carcinoma; HURP; Sorafenib; Taxol resistance

Indexed keywords

HEPATOMA UPREGULATED PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; SHORT HAIRPIN RNA; SORAFENIB; TRANSCRIPTION FACTOR REL; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER RESISTANCE; CELL DEATH; CELL KILLING; CELL PROTECTION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSLATION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

APOPTOSIS; BENZENESULFONATES; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; LEUPEPTINS; LIVER NEOPLASMS; NEOPLASM PROTEINS; NF-KAPPA B; PACLITAXEL; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-REL; PYRIDINES;

EID: 79958154928     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.04.008     Document Type: Article

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