Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs

Journal of Controlled Release

Volumn 152, Issue 1, 2011, Pages 13-20

  Kim, Ji Young ^a   Kim, Sungwon ^a   Pinal, Rodolfo ^a   Park, Kinam ^a,b  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Hydrotropic polymer micelle; Hydrotropy; N,N diethylnicotinamide; N,N dimethylbenzamide; Poorly soluble drug; Solubilization

Indexed keywords

AQUEOUS SOLUBILITY; CO-POLYMER SYSTEMS; COMBINED EFFECT; CONTROLLED RELEASE PROPERTIES; DRUG CANDIDATES; DRUG LOADING; HIGH CONCENTRATION; HYDROPHOBIC BLOCKS; HYDROPHOBIC DRUG; HYDROPHOBIC INTERACTIONS; HYDROTROPES; HYDROTROPIC AGENTS; HYDROTROPIC POLYMER; HYDROTROPY; MICELLAR SOLUBILIZATION; NON-POLYMERIC; ORDERS OF MAGNITUDE; PHARMACEUTICAL FORMULATION; POLYMER MICELLES; POLYMERIC SYSTEMS; POORLY SOLUBLE DRUGS; POORLY WATER-SOLUBLE DRUGS; SOLUBILIZATION; SOLUBILIZERS;

BLOCK COPOLYMERS; COPOLYMERIZATION; DRUG DELIVERY; DRUG INTERACTIONS; ETHYLENE; GLYCOLS; HYDROPHOBICITY; MICELLES; MICROCRYSTALS; ORGANIC SOLVENTS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; SOLUBILITY;

POLYMERS;

COPOLYMER; DRUG VEHICLE; GRISEOFULVIN; HYDROTROPE; MACROGOL; N,N DIMETHYLBENZAMIDE; NIFEDIPINE; NIKETHAMIDE; ORGANIC SOLVENT; PACLITAXEL; POLYMER; PROBUCOL; PROGESTERONE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED RELEASE FORMULATION; COVALENT BOND; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; DRUG STRUCTURE; HYDROPHILICITY; HYDROPHOBICITY; MICELLE; PRIORITY JOURNAL; SOLUBILIZATION;

BENZAMIDES; DRUG DELIVERY SYSTEMS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICELLES; PHARMACEUTICAL VEHICLES; POLYETHYLENE GLYCOLS; POLYMERS; SOLUBILITY;

EID: 79958127433     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.02.014     Document Type: Article

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