The antidepressant effects and mechanism of action of total saponins from the caudexes and leaves of Panax notoginseng in animal models of depression

Phytomedicine

Volumn 18, Issue 8-9, 2011, Pages 731-738

  Xiang, Hui ^a   Liu, Yingxue ^a   Zhang, Baibing ^a   Huang, Junhao ^a,b   Li, Yi ^a   Yang, Bing ^b   Huang, Zhangxin ^b   Xiang, Feijun ^b   Zhang, Hualin ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b Guangdong Medi world Pharmaceutical Co Ltd   (China)

Author keywords

Antidepressant; Monoamine neurotransmitter; Panax notoginseng; Saponins

Indexed keywords

ANTIDEPRESSANT AGENT; DOPAMINE; NORADRENALIN; PANAX NOTOGINSENG EXTRACT; PLANT EXTRACT; SAPONIN; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DOPAMINE BRAIN LEVEL; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; FORCED SWIMMING TEST; IMMOBILIZATION; LOCOMOTION; MALE; MOUSE; NONHUMAN; NORADRENALIN BRAIN LEVEL; PANAX NOTOGINSENG; PLANT LEAF; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROTONIN BRAIN LEVEL; TREATMENT OUTCOME;

ANIMALS; ANTIDEPRESSIVE AGENTS; ATROPHY; BRAIN; CALCIUM; DEPRESSION; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MALE; MICE; MOTOR ACTIVITY; PANAX NOTOGINSENG; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS;

ANIMALIA; MUS; PANAX NOTOGINSENG; RATTUS; RODENTIA;

EID: 79958107012     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.11.014     Document Type: Article

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