Effect of saponins of Panax notoginseng on synaptosomal 45Ca uptake

Acta Pharmacologica Sinica

Volumn 18, Issue 3, 1997, Pages 213-215

  Ma, Li Yan ^a   Xiao, Pei Gen ^a   Liang, Fa Quan ^b   Chi, Mu Geng ^b   Dong, Shi Jian ^b  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

calcium radioisotopes; ginseng; nimodipine; saponins; synaptosomes

Indexed keywords

CALCIUM 45; CALCIUM ANTAGONIST; GINSENG SAPONIN; NIMODIPINE; PANAX NOTOGINSENG EXTRACT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; RAT;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CEREBRAL CORTEX; NIMODIPINE; PANAX; PLANTS, MEDICINAL; RATS; SAPONINS; SYNAPTOSOMES;

EID: 0030960255     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Li LX, Wang ZC, Huang ZH, Zhang YM, Wei JX. Effects of Panax notoginseng saponins on acute cerebral ischemia. Chin Pharmacol Bull 1991; 7: 56-9.
2. 1 on reversible focal brain ischemia in rats. Acta Pharmacol Sin 1996; 17: 44-8.
3. Du RS, Li FK. Protective effect of total saponins of Panax notoginseng on the model of ischemia in neonatal mice heart cell cultures. Chin J Pediatr 1992; 30: 74-6.
4. Akira M, Fumito K, Kiyoshi K. Distribution of hypoxicinduced calcium accumulation in gerbil hippocampal slice. Neurosci Lett 1990; 120: 42-5.
5. Wu JX, Chen JX. Depressant actions of Panax notoginseng saponins on vascular smooth muscles. Acta Pharmacol Sin 1988; 9: 147-52.
6. 2+ influx into myocardial cells. Acta Pharmacol Sin 1990; 11: 213-7.
7. Guerrero-Munoz F, Cerreta KV, Guerrero ML, Leong Way E. Effect of morphine on synaptosomal Ca uptake. J Pharmacol Exp Ther 1979; 209: 132-6.
8. Lowry OH, Rosenbrough NL, Farr AJ, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951; 193: 265-75.
9. Jin LQ, Shi L. Effects of saponins of Panax notoginseng on sodium-potassium-adenosine triphosphatase and caldum-magnesium-adenosine triphosphatase. Acta Pharmacol Sin 1991; 12: 504-6.