Mitragynine inhibits the COX-2 mRNA expression and prostaglandin E 2 production induced by lipopolysaccharide in RAW264.7 macrophage cells

Journal of Ethnopharmacology

Volumn 136, Issue 1, 2011, Pages 75-82

  Utar, Zulkhurnain ^a   Majid, Mohamed Isa Abdul ^a   Adenan, Mohd Ilham ^a,b   Jamil, Mohd Fadzly Amar ^a   Lan, Tan Mei ^a,c  

^a Kemeneterian Sains Teknologi dan Inovasi   (Malaysia)

^b FOREST RESEARCH INSTITUTE MALAYSIA   (Malaysia)

^c ADVANCED MEDICAL AND DENTAL INSTITUTE   (Malaysia)

Author keywords

Anti inflammatory; COX 1; COX 2; Mitragyna speciosa; Mitragynine

Indexed keywords

ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INDOMETACIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITRAGYNINE; PROSTAGLANDIN E2;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENZYME INHIBITION; MACROPHAGE; MOUSE; NONHUMAN; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITRAGYNA; PLANT EXTRACTS; RNA, MESSENGER; SECOLOGANIN TRYPTAMINE ALKALOIDS;

MITRAGYNA SPECIOSA; RUBIACEAE;

EID: 79958102314     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.04.011     Document Type: Article

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