A case report of inpatient detoxification after kratom (Mitragyna speciosa) dependence

European Addiction Research

Volumn 16, Issue 4, 2010, Pages 229-231

  McWhirter, Laura ^a   Morris, Siobhan ^a  

^a Alcohol Problems Service   (United Kingdom)

Author keywords

Kratom; Mitragyna speciosa; Rehabilitation; Substance withdrawal syndrome

Indexed keywords

AMPHETAMINE; CANNABIS; CHLORPROMAZINE; COCAINE; DIAZEPAM; DIHYDROCODEINE; GAMMA GLUTAMYLTRANSFERASE; HERBACEOUS AGENT; INDOLE ALKALOID; KAVA; KRATOM; LOFEXIDINE; LYSERGIDE; MIRTAZAPINE; UNCLASSIFIED DRUG; VALERIAN;

ADULT; ALCOHOLISM; ANXIETY; ANXIETY DISORDER; ARTHRALGIA; ARTICLE; BLOOD EXAMINATION; BLOOD PRESSURE MEASUREMENT; BONE PAIN; CASE REPORT; CHILL; COLD; DEPRESSION; DETOXIFICATION; DISTRESS SYNDROME; DRUG DEPENDENCE; DRUG DEPENDENCE TREATMENT; DRUG DOSE REDUCTION; EPIPHORA; EUPHORIA; FOLLOW UP; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GOOSEFLESH; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; HYPERTENSION; IRRITABILITY; LEISURE; LEUKOCYTE COUNT; MALE; MITRAGYNA; NAUSEA; PHYSICAL EXAMINATION; PRIORITY JOURNAL; PRODUCTIVITY; PRURITUS; PULSE RATE; PUPIL; RESTLESSNESS; RHINORRHEA; RHODIOLA; SELF MEDICATION; SLEEP DISORDER; SPEECH RATE; SPIRULINA; SUBSTANCE ABUSE; SWEATING; TREMOR; VIVID DREAM; WITHDRAWAL SYNDROME; YAWNING;

ADULT; ANXIETY; HUMANS; INPATIENTS; MALE; METABOLIC DETOXICATION, DRUG; MITRAGYNA; SUBSTANCE WITHDRAWAL SYNDROME; TREMOR;

EID: 77956073875     PISSN: 10226877     EISSN: None     Source Type: Journal    
DOI: 10.1159/000320288     Document Type: Article

References (11)

1. Erowid: Kratom: legal status. 1994, updated 2009. http://www.erowid.org/ plants/ kratom/kratom-law.shtml (accessed November 10, 2009).
2. United Nations Office on Drugs and Crime: Patterns and trends of amphetamine-type stimulants and other drugs in East and South-East Asia (and neighbouring regions). 2009. http://www.unodc.org/documents/scientific/ ATS/2009-Patterns-and-Trends.pdf.
3. Babu KM, McCurdy CR, Boyer EW: Opioid receptors and legal highs: Salvia divinorum and Kratom. Clin Toxicol (Phila) 2008; 46: 146-152.
4. León F, Habib E, Adkins JE, Furr EB, McCurdy CR, Cutler SJ: Phytochemical characterization of the leaves of Mitragyna speciosa grown in USA. Nat Prod Commun 2009; 4: 907-910.
5. Takayama H: Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant Mitragyna speciosa. Chem Pharm Bull (Tokyo) 2004; 52: 916-928.
6. Takayama H, Ishikawa H, Kurihara M, Kitajima M, Aimi N, Ponglux D, et al: Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands. J Med Chem 2002; 45: 1949-1956.
7. Matsumoto K, Horie S, Takayama H, Ishikawa H, Aimi N, Ponglux D, et al: Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa. Life Sci 2005; 78: 2-7.
8. Boyer EW, Babu KM, Adkins JE, McCurdy CR, Halpern JH: Self-treatment of opioid withdrawal using kratom ( Mitragynia speciosa Korth). Addiction 2008; 103: 1048-1050.
9. Boyer EW, Babu KM, Macalino GE: Selftreatment of opioid withdrawal with a dietary supplement, Kratom. Am J Addict 2007; 16: 352-356.
10. Matsumoto K, Yamamoto LT, Watanabe K, et al: Inhibitory effect of mitragynine, an analgesic alkaloid from Thai herbal medicine, on neurogenic contraction of the vas deferens. Life Sci 2005; 78: 187-194.
11. Suwanlert S: A study of kratom eaters in Thailand. Bull Narc 1975; 27: 21-27.