20-Hydroxyeicosatetraenoic acid inhibits ATP-induced COX-2 expression via peroxisome proliferator activator receptor-α in vascular smooth muscle cells

British Journal of Pharmacology

Volumn 163, Issue 4, 2011, Pages 815-825

  Liang, Chan Jung ^a   Tseng, Ching Ping ^b   Yang, Chuen Mao ^a   Ma, Yunn Hwa ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

20 hydroxyeicosatetraenoic acid; cyclooxygenase; cytochrome P450; peroxisome proliferator activator receptor; vascular smooth muscle cell

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ADENOSINE TRIPHOSPHATE; CYCLOOXYGENASE 2; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; SHORT HAIRPIN RNA;

ARTICLE; CELL LINE; CELL STRAIN R22D; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GENETIC TRANSFECTION; INHIBITION KINETICS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE; CYCLOOXYGENASE 2; HYDROXYEICOSATETRAENOIC ACIDS; INDOLES; LUCIFERASES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUSCLE, SMOOTH, VASCULAR; PPAR ALPHA; PROMOTER REGIONS, GENETIC; PYRIMIDINES; RATS; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR AP-1;

EID: 79958061270     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01263.x     Document Type: Article

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