Transforming growth factor beta regulates cyclooxygenase-2 in glomerular mesangial cells

Kidney International

Volumn 69, Issue 9, 2006, Pages 1578-1585

  Harding, P ^a,b   Balasubramanian, L ^a   Swegan, J ^a   Stevens, A ^a   Glass II, W F ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b HENRY FORD HOSPITAL   (United States)

Author keywords

COX 2; Mesangial cells; Prostaglandin E synthase; Transforming growth factor beta

Indexed keywords

COLLAGEN TYPE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; THROMBOXANE B2; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; ENZYME INHIBITION; ENZYME REGULATION; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENETIC TRANSCRIPTION; GLOMERULUS; HALF LIFE TIME; KIDNEY INTERSTITIUM; NONHUMAN; NORTHERN BLOTTING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; RNA STABILITY;

ANIMALS; COLLAGEN TYPE I; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KIDNEY GLOMERULUS; MESANGIAL CELLS; NF-KAPPA B; NITROBENZENES; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; RNA STABILITY; RNA, MESSENGER; SULFONAMIDES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 33646526079     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5000323     Document Type: Article

References (48)

1. Roberts AB, Heine UI, Flanders KC, Sporn MB. Transforming growth factor-β: major role in regulation of extracellular matrix. Ann NY Acad Sci 1990; 580: 225-232.
2. Sharma K, Ziyadeh FN. The transforming growth factor-β system and the kidney. Semin Nephrol 1993; 13: 116-128.
3. Ziyadeh FN. The extracellular matrix in diabetic nephropathy. Am J Kidney Diseases 1993; 22: 736-744.
4. Yamamoto T, Nakamura T, Noble NA et al. Expression of transforming growth factor β is elevated in human and experimental diabetic nephropathy. Proc Natl Acad Sci USA 1993; 90: 1814-1818.
5. Han DC, Isono M, Hoffman BB, Ziyadeh FN. High glucose stimulates proliferation and collagen type I synthesis in renal cortical fibroblasts: mediation by autocrine activation of TGFβ. J Am Soc Nephrol 1999; 10: 1891-1899.
6. Wolf G, Sharma K, Chen Y et al. High glucose-induced proliferation in mesangial cells is reversed by autocrine TGFβ. Kidney Int 1992; 42: 647-656.
7. Goldstein RH, Polgar P. The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts. J Biol Chem 1982; 257: 8630-8633.
8. Zahner G, Harendza S, Muller E et al. Prostaglandin E2 stimulates expression of matrix metalloproteinase 2 in cultured rat mesangial cells. Kidney Int 1997; 51: 1116-1123.
9. Xie W, Herschman HR. Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum. J Biol Chem 1996; 271: 31742-31748.
10. DeWitt DL, Meade EA. Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes. Arch Biochem Biophys 1993; 306: 94-102.
11. Jakobsson PJ, Thoren S, Morgenstern R, Samuelsson B. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci USA 1999; 96: 7220-7225.
12. Kawaguchi H, Saito H, Yasuda H. Renal prostaglandins and phospholipase A2 in spontaneously hypertensive rats. J Hypertens 1987; 5: 299-304.
13. Yanagisawa H, Morrisey J, Morrison AR, Klahr S. Eicosanoid production by isolated glomeruli of rats with unilateral ureteral obstruction. Kidney Int 1990; 37: 1528-1535.
14. Schambelan M, Blake S, Sraer J et al. Increased prostaglandin production by glomeruli isolated from rats with streptozotocin-induced diabetes mellitus. J Clin Invest 1985; 75: 404-412.
15. Wang J-L, Cheng H-F, Shappell S, Harris RC. A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats. Kidney Int 2000; 57: 2334-2342.
16. Blume C, Heise G, Muhlfeld A et al. Effect of flosulide, a selective cyclooxygenase-2 inhibitor, on passive Heymann nephritis in the rat. Kidney Int 1999; 56: 1770-1778.
17. Harding P, Glass WF, Scherer S. COX-2 inhibition potentiates the anti-proteinuric effect of enalapril in uninephrectomized SHR. Prostaglandins Leukot Essent Fatty Acids 2003; 68: 17-25.
18. McAnulty RJ, Hernandez-Rodriquez NA, Mutsaers SE et al. Indomethacin suppresses the anti-proliferative effects of transforming growth factor β isoforms on fibroblast cell cultures. Biochem J 1997; 321: 639-643.
19. Diaz A, Chepenik KP, Korn JH et al. Differential regulation of cyclooxygenases 1 and 2 by interleukin-1β, tumor necrosis factor-α, and transforming growth factor-β1 in human lung fibroblasts. Exp Cell Res 1998; 241: 222-229.
20. Yang X, Hou F, Taylor L, Polgar P. Characterization of human cyclooxygenase 2 gene promoter: localization of a TGF-beta response element. Biochim Biophys Acta 1997; 1350: 287-292.
21. Sheng H, Shao J, Dixon DA et al. Transforming growth factor β-1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA. J Biol Chem 2000; 275: 6628-6635.
22. Srivastava SK, Tetsuka T, Daphna-Iken D, Morrison AR. IL-1β stabilizes COX-2 mRNA in renal mesangial cells: role of 3′ untranslated region. Am J Physiol 1994; 267: F504-F508.
23. Fong CY, Pang L, Holland E, Knox AJ. TGFβ1 stimulates IL-8 release, COX-2 expression and PGE2 release in human airway smooth muscle cells. Am J Physiol 2000; 279: L201-L207.
24. Inoue H, Yokoyama C, Hara S et al. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. J Biol Chem 1995; 270: 24965-24971.
25. Ristimaki A, Narko K, Hla T. Down-regulation of cytokine-induced cyclooxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation. Biochem J 1996; 318: 325-331.
26. Newton R, Seybold J, Liu SF, Barnes PJ. Alternate COX-2 transcripts are differentially regulated: implications for post-transcriptional control. Biochem Biophys Res Commun 1997; 234: 85-89.
27. Kosaka T, Miyata A, Ihara H et al. Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. Eur J Biochem 1984; 221: 889-897.
28. Maldve RE, Kim Y, Muga SJ, Fischer SM. Prostaglandin E2 regulation of cyclooxygenase-2 expression in keratinocytes is mediated via cyclic nucleotide-linked prostaglandin receptors. J Lipid Res 2000; 41: 873-881.
29. Wang J-L, Cheng H-F, Harris RC. Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension. Hypertension 1999; 34: 96-101.
30. Inoue H, Tanabe T, Umesono K. Feedback control of cyclooxygenase-2 expression through PPARγ. J Biol Chem 2000; 275: 28028-28032.
31. Sirois J, Ley LO, Simmons DL, Richards JS. Characterization and hormonal regulation of the promoter of the rat prostaglandin endoperoxide synthase 2 gene in granulosa cells. J Biol Chem 1993; 268: 12199-12206.
32. Gaedeke J, Noble NA, Border WA. Curcumin blocks multiple sites of the TGF-beta signaling cascade in renal cells. Kidney Int 2004; 66: 112-120.
33. Wong BC, Jiang XH, Lin MC et al. Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase. Gastroenterology 2004; 126: 136-147.
34. Kim S-J, Jeong H-J, Choi I-Y et al. Cyclooxygenase-2 inhibitor SC-236 [4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1-pyrazol-1-1] benzenesulfonamide] suppresses nuclear factor-κB activation and phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase, and c-Jun N-terminal kinase in human mast cell line cells. J Pharmacol Exp Ther 2005; 314: 27-34.
35. Dean JLE, Brook M, Clark AR, Saklatvala J. P38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J Biol Chem 1999; 274: 264-269.
36. Brock TG, McNish RW, Peters-Golden M. Arachidonic acid is preferentially metabolized by cyclooxygenase-2 to prostacyclin and prostaglandin E2. J Biol Chem 1999; 274: 11660-11666.
37. Murakami M, Naraba H, Tanioka T et al. Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J Biol Chem 2000; 275: 32783-32792.
38. Petry C, Fritz G, Pfeilschifter J, Huwiler A. Inhibition of Rho modulates cytokine-induced prostaglandin formation in rat mesangial cells. Biochim Biophys Acta 2004; 1636: 108-118.
39. Campean V, Theilig F, Paliege A et al. Key enzymes for renal prostaglandin synthesis: site-specific expression in rodent kidney (rat, mouse). Am J Physiol Renal Physiol 2003; 285: F19-F32.
40. Kelefiotis D, Bresnahan BA, Stratidakis I, Lianos EA. Eicosanoid-induced growth and signaling events in rat glomerular mesangial cells. Prostaglandins 1995; 49: 269-283.
41. Togawa M, Haneda M, Araki S et al. Beraprost sodium, an analogue of prostacyclin, induces the expression of mitogen-activated protein kinase phosphatase and inhibits the proliferation of cultured mesangial cells. Eur J Pharmacol 1997; 336: 291-294.
42. Miyajima A, Ito K, Asano T et al. Does cyclooxygenase-2 inhibitor prevent renal tissue damage in unilateral ureteral obstruction? J Urology 2001; 166: 1124-1129.
43. Cheng H-F, Wang CJ, Moeckel GW et al. Cyclooxygenase-2 inhibitor blocks expression of mediators of renal injury in a model of diabetes and hypertension. Kidney Int 2002; 62: 929-939.
44. Richter CM, Godes M, Wagner C et al. Chronic cyclooxygenase-2 inhibition does not alter blood pressure and kidney function in renovascular hypertensive rats. J Hypertens 2004; 22: 191-198.
45. Glass WF, Teng PR, Haney LB. Extracellular matrix deposition and hillock formation in human mesangial cells in culture without serum. J Am Soc Nephrol 1996; 7: 2230-2243.
46. Sehgal PB, Darnell Jr JE, Tamm I. The inhibition by DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells. Cell 1976; 9: 473-480.
47. Futaki N, Takahashi S, Yokoyama M et al. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins 1994; 47: 55-59.
48. Stegeman H, Stalder K. Determination of hydroxyproline. Clin Chimica Acta 1967; 18: 267-273.