Contribution of Vasoactive Eicosanoids and Nitric Oxide Production to the Effect of Selective Cyclooxygenase-2 Inhibitor, NS-398, on Endotoxin-Induced Hypotension in Rats

Basic and Clinical Pharmacology and Toxicology

Volumn 107, Issue 5, 2010, Pages 877-882

  Tunctan, Bahar ^a   Korkmaz, Belma ^a   Cuez, Tuba ^a   Kemal Buharalioglu, C ^a   Sahan Firat, Seyhan ^a   Falck, John ^b   Malik, Kafait U ^c  

^a MERSIN UNIVERSITY   (Turkey)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; 6 KETO PROSTAGLANDIN F1 ALPHA; ENDOTOXIN; ICOSANOID; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NITRIC OXIDE; NITRITE; PROSTACYCLIN; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E2; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTOXEMIA; ENZYME INHIBITION; HEART; HEART RATE; HYPOTENSION; KIDNEY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPTIC SHOCK; SUPERIOR MESENTERIC ARTERY; THORACIC AORTA;

ANIMALS; BLOOD PRESSURE; CYCLOOXYGENASE 2 INHIBITORS; EICOSANOIDS; HYPOTENSION; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE; NITROBENZENES; RATS; RATS, WISTAR; SHOCK, SEPTIC; SULFONAMIDES; TIME FACTORS; VASOCONSTRICTION; VASODILATION;

RATTUS; RATTUS NORVEGICUS;

EID: 78649616594     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2010.00589.x     Document Type: Article

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