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Volumn 339, Issue 1-2, 2011, Pages 34-44

Binding of " AT4 receptor" ligands to insulin regulated aminopeptidase (IRAP) in intact Chinese hamster ovary cells

Author keywords

AL 11; Ang IV; CHO cells; Internalization; IRAP; Radioligand binding

Indexed keywords

AL 11; AMINOPEPTIDASE; ANGIOTENSIN II; ANGIOTENSIN II [3-8]; ANGIOTENSIN II [3-8] RECEPTOR; ANGIOTENSIN RECEPTOR; INSULIN REGULATED AMINOPEPTIDASE; RADIOLIGAND; UNCLASSIFIED DRUG;

EID: 79958025200     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2011.03.005     Document Type: Article
Times cited : (13)

References (70)
  • 4
    • 77956850748 scopus 로고    scopus 로고
    • Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays
    • Charlton S., Vauquelin G. Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays. Br. J. Pharmacol. 2010, 161:1250-1265.
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 1250-1265
    • Charlton, S.1    Vauquelin, G.2
  • 5
    • 0033532555 scopus 로고    scopus 로고
    • Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor
    • Chen H., Roques B.P., Fournié-Zaluski M.C. Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg. Med. Chem. Lett. 1999, 9:1511-1516.
    • (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 1511-1516
    • Chen, H.1    Roques, B.P.2    Fournié-Zaluski, M.C.3
  • 6
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
    • Cheng Y., Prusoff W.H. Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem. Pharmacol. 1973, 22:3099-3108.
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 7
    • 16644394144 scopus 로고    scopus 로고
    • Effects of geometry of the immunological synapse on the delivery of effector molecules
    • Coombs D., Goldstein B. Effects of geometry of the immunological synapse on the delivery of effector molecules. Biophys. J. 2004, 87:2215-2220.
    • (2004) Biophys. J. , vol.87 , pp. 2215-2220
    • Coombs, D.1    Goldstein, B.2
  • 14
    • 47849111875 scopus 로고    scopus 로고
    • The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus-potential role in modulation of glucose uptake in neurones?
    • Fernando R.N., Albiston A.L., Chai S.Y. The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus-potential role in modulation of glucose uptake in neurones?. Eur. J. Neurosci. 2008, 28:588-598.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 588-598
    • Fernando, R.N.1    Albiston, A.L.2    Chai, S.Y.3
  • 15
    • 0032970721 scopus 로고    scopus 로고
    • Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected Chinese hamster ovary cells
    • Fierens F.L.P., Vanderheyden P.M.L., De Backer J.-P., Vauquelin G. Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected Chinese hamster ovary cells. Eur. J. Pharmacol. 1999, 367:413-422.
    • (1999) Eur. J. Pharmacol. , vol.367 , pp. 413-422
    • Fierens, F.L.P.1    Vanderheyden, P.M.L.2    De Backer, J.-P.3    Vauquelin, G.4
  • 17
    • 0034723395 scopus 로고    scopus 로고
    • Insulin-responsive aminopeptidase trafficking in 3T3-L1 adipocytes
    • Garza L.A., Birnbaum M.J. Insulin-responsive aminopeptidase trafficking in 3T3-L1 adipocytes. J. Biol. Chem. 2000, 275:2560-2567.
    • (2000) J. Biol. Chem. , vol.275 , pp. 2560-2567
    • Garza, L.A.1    Birnbaum, M.J.2
  • 18
    • 0031984823 scopus 로고    scopus 로고
    • Evaluation of the importance of rebinding to receptors in slowing the approach to equilibrium of high-affinity PET and SPECT radiotracers
    • Gifford A.N., Gatley J., Volkow N.D. Evaluation of the importance of rebinding to receptors in slowing the approach to equilibrium of high-affinity PET and SPECT radiotracers. Synapse 1998, 28:167-175.
    • (1998) Synapse , vol.28 , pp. 167-175
    • Gifford, A.N.1    Gatley, J.2    Volkow, N.D.3
  • 19
    • 19644372736 scopus 로고    scopus 로고
    • P115 interacts with the GLUT4 vesicle protein IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation
    • Hosaka T., Brooks C.C., Presman E., Kim S.K., Zhang Z., Breen M., Gross D.N., Sztul E., Pilch P.F. p115 interacts with the GLUT4 vesicle protein IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation. Mol. Biol. Cell 2005, 16:2882-2890.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2882-2890
    • Hosaka, T.1    Brooks, C.C.2    Presman, E.3    Kim, S.K.4    Zhang, Z.5    Breen, M.6    Gross, D.N.7    Sztul, E.8    Pilch, P.F.9
  • 20
    • 33947380595 scopus 로고    scopus 로고
    • Comparative In Vitro degradation of the human hemorphin LVV-H7 in mammalian plasma analysed by capillary zone electrophoresis and mass spectrometry
    • Johna H., Schulza S., Forssmann W.-G. Comparative In Vitro degradation of the human hemorphin LVV-H7 in mammalian plasma analysed by capillary zone electrophoresis and mass spectrometry. Biopharm. Drug Dispos. 2007, 28:73-85.
    • (2007) Biopharm. Drug Dispos. , vol.28 , pp. 73-85
    • Johna, H.1    Schulza, S.2    Forssmann, W.-G.3
  • 21
    • 0032504203 scopus 로고    scopus 로고
    • Identification of an insulin-responsive, slow endocytic recycling mechanism in Chinese hamster ovary cells
    • Johnson A.O., Subtil A., Petrush R., Kobylarz K., Keller S.R., McGraw T.E. Identification of an insulin-responsive, slow endocytic recycling mechanism in Chinese hamster ovary cells. J. Biol. Chem. 1998, 273:17968-17977.
    • (1998) J. Biol. Chem. , vol.273 , pp. 17968-17977
    • Johnson, A.O.1    Subtil, A.2    Petrush, R.3    Kobylarz, K.4    Keller, S.R.5    McGraw, T.E.6
  • 22
    • 0035157903 scopus 로고    scopus 로고
    • A di-leucine sequence and a cluster of acidic amino acids are required for dynamic retention in the endosomal recycling compartment of fibroblasts
    • Johnson A.O., Lampson M.A., McGraw T.E. A di-leucine sequence and a cluster of acidic amino acids are required for dynamic retention in the endosomal recycling compartment of fibroblasts. Mol. Biol. Cell 2001, 12:367-381.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 367-381
    • Johnson, A.O.1    Lampson, M.A.2    McGraw, T.E.3
  • 23
    • 0027956154 scopus 로고
    • Gp160, a tissue-specific marker for insulin-activated glucose transport
    • Kandror K.V., Pilch P.F. gp160, a tissue-specific marker for insulin-activated glucose transport. Proc. Natl. Acad. Sci. U.S.A. 1994, 8017-8021.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , pp. 8017-8021
    • Kandror, K.V.1    Pilch, P.F.2
  • 24
    • 0036246301 scopus 로고    scopus 로고
    • Acyl-coenzyme A dehydrogenases are localized on GLUT4-containing vesicles via association with insulin-regulated aminopeptidase in a mannerk dependent on its dileucine motif
    • Katagiri H., Asano T., Yamada T., Aoyama T., Fukushima Y., Kikuchi M., Kodama T., Oka Y. Acyl-coenzyme A dehydrogenases are localized on GLUT4-containing vesicles via association with insulin-regulated aminopeptidase in a mannerk dependent on its dileucine motif. Mol. Endocrinol. 2002, 16:1049-1059.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1049-1059
    • Katagiri, H.1    Asano, T.2    Yamada, T.3    Aoyama, T.4    Fukushima, Y.5    Kikuchi, M.6    Kodama, T.7    Oka, Y.8
  • 25
    • 0028817838 scopus 로고
    • Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles
    • Keller S.R., Scott H.M., Mastick C.C., Aebersold R., Lienhard G.E. Cloning and characterization of a novel insulin-regulated membrane aminopeptidase from Glut4 vesicles. J. Biol. Chem. 1995, 270:23612-23618.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23612-23618
    • Keller, S.R.1    Scott, H.M.2    Mastick, C.C.3    Aebersold, R.4    Lienhard, G.E.5
  • 26
    • 0030756892 scopus 로고    scopus 로고
    • Endocytosis and recycling of G protein-coupled receptors
    • Koenig J.A., Edwardson J.M. Endocytosis and recycling of G protein-coupled receptors. Trends Pharmacol. Sci. 1997, 18:276-287.
    • (1997) Trends Pharmacol. Sci. , vol.18 , pp. 276-287
    • Koenig, J.A.1    Edwardson, J.M.2
  • 27
    • 0032374053 scopus 로고    scopus 로고
    • Fates of endocytosed somatostatin sst2 receptors and associated agonists
    • Koenig J.A., Kaur R., Dodgeon I., Edwardson M., Humphrey P.A. Fates of endocytosed somatostatin sst2 receptors and associated agonists. Biochem. J. 1998, 336:291-298.
    • (1998) Biochem. J. , vol.336 , pp. 291-298
    • Koenig, J.A.1    Kaur, R.2    Dodgeon, I.3    Edwardson, M.4    Humphrey, P.A.5
  • 28
    • 0034472887 scopus 로고    scopus 로고
    • Demonstration of insulin-responsive trafficking of GLUT4 and vpTR in fibroblasts
    • Lampson M.A., Racz A., Cushman S.W., McGraw T.E. Demonstration of insulin-responsive trafficking of GLUT4 and vpTR in fibroblasts. J. Cell Sci. 2000, 113:4065-4076.
    • (2000) J. Cell Sci. , vol.113 , pp. 4065-4076
    • Lampson, M.A.1    Racz, A.2    Cushman, S.W.3    McGraw, T.E.4
  • 30
    • 0037189515 scopus 로고    scopus 로고
    • Angiotensin IV is a potent agonist for constitutive active human AT1 receptors. Distinct roles of the N- and C-terminal amino acid residues of angiotensin II in human AT1 receptor activation
    • Le M.T., Vanderheyden P.M.L., Szaszák M., Hunyady L., Vauquelin G. Angiotensin IV is a potent agonist for constitutive active human AT1 receptors. Distinct roles of the N- and C-terminal amino acid residues of angiotensin II in human AT1 receptor activation. J. Biol. Chem. 2002, 277:23107-23110.
    • (2002) J. Biol. Chem. , vol.277 , pp. 23107-23110
    • Le, M.T.1    Vanderheyden, P.M.L.2    Szaszák, M.3    Hunyady, L.4    Vauquelin, G.5
  • 31
    • 18844439930 scopus 로고    scopus 로고
    • Ligand binding and functional properties of human angiotensin AT1 receptors in transiently and stably expressed CHO-K1 cells
    • Le M.T., De Backer J.P., Hunyady L., Vanderheyden P.M., Vauquelin G. Ligand binding and functional properties of human angiotensin AT1 receptors in transiently and stably expressed CHO-K1 cells. Eur. J. Pharmacol. 2005, 513:35-45.
    • (2005) Eur. J. Pharmacol. , vol.513 , pp. 35-45
    • Le, M.T.1    De Backer, J.P.2    Hunyady, L.3    Vanderheyden, P.M.4    Vauquelin, G.5
  • 33
    • 0022555668 scopus 로고
    • Peripheral 5-HT2-like receptors. Can they be classified with the available antagonists?
    • Leff P., Martin G.R. Peripheral 5-HT2-like receptors. Can they be classified with the available antagonists?. Br. J. Pharmacol. 1986, 88:585-593.
    • (1986) Br. J. Pharmacol. , vol.88 , pp. 585-593
    • Leff, P.1    Martin, G.R.2
  • 34
    • 0037817386 scopus 로고    scopus 로고
    • Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP)
    • Lew R.A., Mustafa T., Ye S., McDowall S.G., Chai S.Y., Albiston A.L. Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP). J. Neurochem. 2003, 86:344-350.
    • (2003) J. Neurochem. , vol.86 , pp. 344-350
    • Lew, R.A.1    Mustafa, T.2    Ye, S.3    McDowall, S.G.4    Chai, S.Y.5    Albiston, A.L.6
  • 35
    • 0035172441 scopus 로고    scopus 로고
    • Identification of discrete classes of endosome-derived small vesicles as a major cellular pool for recycling membrane proteins
    • Lim S.N., Bonzelius F., Low S.H., Wille H., Weimbs T., Herman G.A. Identification of discrete classes of endosome-derived small vesicles as a major cellular pool for recycling membrane proteins. Mol. Biol. Cell 2001, 12:981-995.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 981-995
    • Lim, S.N.1    Bonzelius, F.2    Low, S.H.3    Wille, H.4    Weimbs, T.5    Herman, G.A.6
  • 37
    • 70349200782 scopus 로고    scopus 로고
    • The replacement of His(4) in Angiotensin IV by conformationally constrained residues provides highly potent and selective analogs
    • Lukaszuk A., Demaegdt H., Feytens D., Vanderheyden P., Vauquelin G., Tourwé D. The replacement of His(4) in Angiotensin IV by conformationally constrained residues provides highly potent and selective analogs. J. Med. Chem. 2009, 52:5612-5618.
    • (2009) J. Med. Chem. , vol.52 , pp. 5612-5618
    • Lukaszuk, A.1    Demaegdt, H.2    Feytens, D.3    Vanderheyden, P.4    Vauquelin, G.5    Tourwé, D.6
  • 38
    • 0036473397 scopus 로고    scopus 로고
    • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
    • Luttrell L.M., Lefkowitz R.J. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J. Cell Sci. 2002, 115:455-465.
    • (2002) J. Cell Sci. , vol.115 , pp. 455-465
    • Luttrell, L.M.1    Lefkowitz, R.J.2
  • 39
    • 68949170699 scopus 로고    scopus 로고
    • Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: application to (R)-dimethindene occupancy of central histamine H1 receptors
    • Malany S., Hernandez L.M., Smith W.F., Crowe P.D., Hoare S.R.J. Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: application to (R)-dimethindene occupancy of central histamine H1 receptors. J. Recept. Signal Transduct. Res. 2009, 29:84-93.
    • (2009) J. Recept. Signal Transduct. Res. , vol.29 , pp. 84-93
    • Malany, S.1    Hernandez, L.M.2    Smith, W.F.3    Crowe, P.D.4    Hoare, S.R.J.5
  • 40
    • 0027992046 scopus 로고
    • Characterization of a major protein in GLUT4 vesicles. Concentration in the vesicles and insulin-stimulated translocation to the plasma membrane
    • Mastick C.C., Aebersold R., Lienhard G.E. Characterization of a major protein in GLUT4 vesicles. Concentration in the vesicles and insulin-stimulated translocation to the plasma membrane. J. Biol. Chem. 1994, 269:6089-6092.
    • (1994) J. Biol. Chem. , vol.269 , pp. 6089-6092
    • Mastick, C.C.1    Aebersold, R.2    Lienhard, G.E.3
  • 41
    • 0034850467 scopus 로고    scopus 로고
    • Expression of placental leucine aminopeptidase/oxytocinase in neuronal cells and its action on neuronal peptides
    • Matsumoto H., Nagasaka T., Hattori A., Rogi T., Tsuruoka N., Mizutani S., Tsujimoto M. Expression of placental leucine aminopeptidase/oxytocinase in neuronal cells and its action on neuronal peptides. Eur. J. Biochem. 2001, 268:3259-3266.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 3259-3266
    • Matsumoto, H.1    Nagasaka, T.2    Hattori, A.3    Rogi, T.4    Tsuruoka, N.5    Mizutani, S.6    Tsujimoto, M.7
  • 42
    • 0029752791 scopus 로고    scopus 로고
    • Endocytosis and molecular sorting
    • Mellman I. Endocytosis and molecular sorting. Annu. Rev. Cell Biol. 1996, 12:575-625.
    • (1996) Annu. Rev. Cell Biol. , vol.12 , pp. 575-625
    • Mellman, I.1
  • 43
    • 0034522250 scopus 로고    scopus 로고
    • Oxytocin stimulates the translocation of oxytocinase of human vascular endothelial cells via activation of oxytocin receptors
    • Nakamura H., Itakuara A., Okamura M., Ito M., Iwase A., Nakanishi Y., Okada M., Nagasaka T., Mizutani S. Oxytocin stimulates the translocation of oxytocinase of human vascular endothelial cells via activation of oxytocin receptors. Endocrinology 2000, 141:4481-4485.
    • (2000) Endocrinology , vol.141 , pp. 4481-4485
    • Nakamura, H.1    Itakuara, A.2    Okamura, M.3    Ito, M.4    Iwase, A.5    Nakanishi, Y.6    Okada, M.7    Nagasaka, T.8    Mizutani, S.9
  • 44
    • 77956840539 scopus 로고    scopus 로고
    • Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a " two-step" competition binding approach
    • Packeu A., Wennerberg M., Ballendran A., Vauquelin G. Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a " two-step" competition binding approach. Br. J. Pharmacol. 2010, 161:1311-1328.
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 1311-1328
    • Packeu, A.1    Wennerberg, M.2    Ballendran, A.3    Vauquelin, G.4
  • 45
    • 77952566351 scopus 로고    scopus 로고
    • Non-competitive interaction between raclopride and spiperone on human D2L-receptors in intact recombinant Chinese hamster ovary cells
    • Packeu A., De Backer J.P., Vauquelin G. Non-competitive interaction between raclopride and spiperone on human D2L-receptors in intact recombinant Chinese hamster ovary cells. Fund. Clin. Pharmacol. 2010, 24:283-291.
    • (2010) Fund. Clin. Pharmacol. , vol.24 , pp. 283-291
    • Packeu, A.1    De Backer, J.P.2    Vauquelin, G.3
  • 46
    • 33749365543 scopus 로고    scopus 로고
    • Interaction of the Akt substrate AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase
    • Peck G.R., Ye S., Pham V., Fernando R.N., Macaulay S.L., Chai S.Y., Albiston A.L. Interaction of the Akt substrate AS160, with the glucose transporter 4 vesicle marker protein, insulin-regulated aminopeptidase. Mol. Endocrinol. 2006, 20:2576-2583.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 2576-2583
    • Peck, G.R.1    Ye, S.2    Pham, V.3    Fernando, R.N.4    Macaulay, S.L.5    Chai, S.Y.6    Albiston, A.L.7
  • 47
    • 0018868014 scopus 로고
    • Opiate antagonist receptor binding in vivo: evidence for a new receptor binding model
    • Perry D.C., Mullis K.B., Øie S., Sadée W. Opiate antagonist receptor binding in vivo: evidence for a new receptor binding model. Brain Res. 1980, 199:49-61.
    • (1980) Brain Res. , vol.199 , pp. 49-61
    • Perry, D.C.1    Mullis, K.B.2    Øie, S.3    Sadée, W.4
  • 49
  • 51
    • 0345269234 scopus 로고    scopus 로고
    • In vivo processing of LVV-hemorphin-7 in rat brain and blood utilizing microdialysis combined with electrospray mass spectrometry
    • Sanderson Nydahl K., Pierson J., Nyberg F., Caprioli R.M., Andren P.E. In vivo processing of LVV-hemorphin-7 in rat brain and blood utilizing microdialysis combined with electrospray mass spectrometry. Rapid Commun. Mass Spectrom. 2003, 17:838-844.
    • (2003) Rapid Commun. Mass Spectrom. , vol.17 , pp. 838-844
    • Sanderson Nydahl, K.1    Pierson, J.2    Nyberg, F.3    Caprioli, R.M.4    Andren, P.E.5
  • 52
    • 33646873478 scopus 로고    scopus 로고
    • Diffusion delays and unstirred layer effects at monolayer cultures of Chinese hamster ovary cells: radioligand binding, confocal microscopy, and mathematical simulations
    • Spivak C.E., Oz M., Beglan C.L., Shrager R.I. Diffusion delays and unstirred layer effects at monolayer cultures of Chinese hamster ovary cells: radioligand binding, confocal microscopy, and mathematical simulations. Cell Biochem. Biophys. 2006, 45:43-58.
    • (2006) Cell Biochem. Biophys. , vol.45 , pp. 43-58
    • Spivak, C.E.1    Oz, M.2    Beglan, C.L.3    Shrager, R.I.4
  • 53
    • 33846117473 scopus 로고    scopus 로고
    • Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat
    • Stragier B., Demaegdt H., De Bundel D., Smolders I., Sarre S., Vauquelin G., Ebinger G., Michotte Y., Vanderheyden P. Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat. Brain Res. 2007, 1131:97-105.
    • (2007) Brain Res. , vol.1131 , pp. 97-105
    • Stragier, B.1    Demaegdt, H.2    De Bundel, D.3    Smolders, I.4    Sarre, S.5    Vauquelin, G.6    Ebinger, G.7    Michotte, Y.8    Vanderheyden, P.9
  • 55
    • 0034681365 scopus 로고    scopus 로고
    • Characterization of the insulin-regulated endocytic recycling mechanism in 3T3-L1 adipocytes using a novel reporter molecule
    • Subtil A., Lampson M.A., Keller S.R., McGraw T.E. Characterization of the insulin-regulated endocytic recycling mechanism in 3T3-L1 adipocytes using a novel reporter molecule. J. Biol. Chem. 2000, 275:4787-4795.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4787-4795
    • Subtil, A.1    Lampson, M.A.2    Keller, S.R.3    McGraw, T.E.4
  • 57
  • 58
    • 0032942443 scopus 로고    scopus 로고
    • Distinction between surmountable and insurmountable selective AT1 receptor antagonists by use of CHO-K1 cells expressing human angiotensin II AT1 receptors
    • Vanderheyden P.M.L., Fierens F.L.P., De Backer J.-P., Fraeyman N., Vauquelin G. Distinction between surmountable and insurmountable selective AT1 receptor antagonists by use of CHO-K1 cells expressing human angiotensin II AT1 receptors. Br. J. Pharmacol. 1999, 126:1057-1065.
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 1057-1065
    • Vanderheyden, P.M.L.1    Fierens, F.L.P.2    De Backer, J.-P.3    Fraeyman, N.4    Vauquelin, G.5
  • 59
    • 79958051359 scopus 로고    scopus 로고
    • Metabolism of AT4 receptor binding peptides in the presence of cell membranes of Chinese hamster ovary cells
    • Vanderheyden P.M.L., De Backer J.P., Demaegdt H., Matziari M., Vauquelin G., Yiotakis A. Metabolism of AT4 receptor binding peptides in the presence of cell membranes of Chinese hamster ovary cells. FEBS J. 2008, 275:322.
    • (2008) FEBS J. , vol.275 , pp. 322
    • Vanderheyden, P.M.L.1    De Backer, J.P.2    Demaegdt, H.3    Matziari, M.4    Vauquelin, G.5    Yiotakis, A.6
  • 62
    • 34548515751 scopus 로고    scopus 로고
    • Kinetic versus allosteric mechanisms to explain insurmountable antagonism and delayed ligand dissociation
    • Vauquelin G., Szczuka A. Kinetic versus allosteric mechanisms to explain insurmountable antagonism and delayed ligand dissociation. Neurochem. Int. 2007, 51:254-260.
    • (2007) Neurochem. Int. , vol.51 , pp. 254-260
    • Vauquelin, G.1    Szczuka, A.2
  • 63
    • 77956309074 scopus 로고    scopus 로고
    • Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug action
    • Vauquelin G., Charlton S. Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug action. Br. J. Pharmacol. 2010, 161:488-508.
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 488-508
    • Vauquelin, G.1    Charlton, S.2
  • 64
    • 77956805081 scopus 로고    scopus 로고
    • Rebinding: or why drugs may act longer in vivo than expected from their in vitro target residence time
    • Vauquelin G. Rebinding: or why drugs may act longer in vivo than expected from their in vitro target residence time. Expert Opin. Drug Discov. 2010, 5:927-941.
    • (2010) Expert Opin. Drug Discov. , vol.5 , pp. 927-941
    • Vauquelin, G.1
  • 66
    • 0030801363 scopus 로고    scopus 로고
    • The amino terminus of insulin-responsive aminopeptidase causes Glut4 translocation in 3T3-L1 adipocytes
    • Waters S.B., D'Auria M., Martin S.S., Nguyen C., Kozma L.M., Luskey K.L. The amino terminus of insulin-responsive aminopeptidase causes Glut4 translocation in 3T3-L1 adipocytes. J. Biol. Chem. 1997, 272:23323-23327.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23323-23327
    • Waters, S.B.1    D'Auria, M.2    Martin, S.S.3    Nguyen, C.4    Kozma, L.M.5    Luskey, K.L.6
  • 69
    • 39049161519 scopus 로고    scopus 로고
    • Angiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targets
    • Wright J.W., Yamamoto B.J., Harding J.W. Angiotensin receptor subtype mediated physiologies and behaviors: new discoveries and clinical targets. Prog. Neurobiol. 2008, 84:157-181.
    • (2008) Prog. Neurobiol. , vol.84 , pp. 157-181
    • Wright, J.W.1    Yamamoto, B.J.2    Harding, J.W.3
  • 70
    • 33847701165 scopus 로고    scopus 로고
    • Insulin-stimulated exocytosis of GLUT4 is enhanced by IRAP and its partner tankyrase
    • Yeh T.Y.J., Sbodio J.I., Tsun Z.Y., Luo B., Chi N.W. Insulin-stimulated exocytosis of GLUT4 is enhanced by IRAP and its partner tankyrase. Biochem. J. 2007, 402:279-290.
    • (2007) Biochem. J. , vol.402 , pp. 279-290
    • Yeh, T.Y.J.1    Sbodio, J.I.2    Tsun, Z.Y.3    Luo, B.4    Chi, N.W.5


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