메뉴 건너뛰기




Volumn 367, Issue 2-3, 1999, Pages 413-422

Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-tranfected Chinese hamster ovary cells

Author keywords

3H Candesartan; Angiotensin II; Dissociation; Non peptide antagonist; Reassociation; Recovery

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; CANDESARTAN; LOSARTAN; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; ANTIHYPERTENSIVE AGENT; BENZIMIDAZOLE DERIVATIVE; INOSITOL PHOSPHATE; LIGAND; TETRAZOLE DERIVATIVE;

EID: 0032970721     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00965-0     Document Type: Article
Times cited : (88)

References (27)
  • 1
    • 0031041454 scopus 로고    scopus 로고
    • 1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane heIices III and VII
    • 1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane heIices III and VII. J. Biol. Chem. 272:1997;4245-4251.
    • (1997) J. Biol. Chem. , vol.272 , pp. 4245-4251
    • Balmforth, A.J.1    Lee, A.L.2    Warburton, P.3    Donnelly, D.4    Ball, S.G.5
  • 5
    • 0022885863 scopus 로고
    • The serotonin-S2 receptor: A receptor, transducer coupling model to explain insurmountable antagonist effects
    • De Chaffoy de Courcelles D., Leysen J.E., Roevens P., Van Belle H. The serotonin-S2 receptor: a receptor, transducer coupling model to explain insurmountable antagonist effects. Drug Dev. Res. 8:1986;173-178.
    • (1986) Drug Dev. Res. , vol.8 , pp. 173-178
    • De Chaffoy De Courcelles, D.1    Leysen, J.E.2    Roevens, P.3    Van Belle, H.4
  • 7
    • 0020955681 scopus 로고
    • Desensitization, two-state receptors and pharmacological parameters
    • Gero A. Desensitization, two-state receptors and pharmacological parameters. J. Theor. Biol. 103:1983;137-161.
    • (1983) J. Theor. Biol. , vol.103 , pp. 137-161
    • Gero, A.1
  • 8
    • 0026536743 scopus 로고
    • Identification of two subtypes in the rat type I angiotensin II
    • Iwai N., Inagami T. Identification of two subtypes in the rat type I angiotensin II. FEBS Lett. 298:1992;257-260.
    • (1992) FEBS Lett. , vol.298 , pp. 257-260
    • Iwai, N.1    Inagami, T.2
  • 9
    • 0026751991 scopus 로고
    • Angiotensin II type-1 receptor subtype cDNAs: Differential tissue expression and hormonal regulation
    • Kakar S.S., Sellers J.C., Devor D.C., Musgrove L.C., Neill J.D. Angiotensin II type-1 receptor subtype cDNAs: differential tissue expression and hormonal regulation. Biochem. Biophys. Res. Commun. 183:1992;1090-1096.
    • (1992) Biochem. Biophys. Res. Commun. , vol.183 , pp. 1090-1096
    • Kakar, S.S.1    Sellers, J.C.2    Devor, D.C.3    Musgrove, L.C.4    Neill, J.D.5
  • 10
    • 0029894243 scopus 로고    scopus 로고
    • Disposition of the new angiotensin II receptor antagonist candesartan cilexetil in rats and dogs
    • Kondo T., Yoshida K., Yoshimura Y., Motohashi M., Tanayama S. Disposition of the new angiotensin II receptor antagonist candesartan cilexetil in rats and dogs. Arzneim.-Forsch./Drug Res. 46:1996;594-600.
    • (1996) Arzneim.-Forsch./Drug Res. , vol.46 , pp. 594-600
    • Kondo, T.1    Yoshida, K.2    Yoshimura, Y.3    Motohashi, M.4    Tanayama, S.5
  • 11
    • 0030218059 scopus 로고    scopus 로고
    • Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation
    • Kostenis E., Mohr K. Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation. Trends Pharmacol. Sci. 17:1996;280-283.
    • (1996) Trends Pharmacol. Sci. , vol.17 , pp. 280-283
    • Kostenis, E.1    Mohr, K.2
  • 12
    • 0026510753 scopus 로고
    • Evidence that the apparent complexity of receptor antagonism by angiotensin II analogues is due to a reversible and synoptic action
    • Liu Y.J., Shankley N.P., Welsh N.J., Black J.W. Evidence that the apparent complexity of receptor antagonism by angiotensin II analogues is due to a reversible and synoptic action. Br. J. Pharmacol. 106:1992;233-241.
    • (1992) Br. J. Pharmacol. , vol.106 , pp. 233-241
    • Liu, Y.J.1    Shankley, N.P.2    Welsh, N.J.3    Black, J.W.4
  • 14
    • 0028973086 scopus 로고
    • Interaction of Phe8 of angiotensin II with Lys199 and His256 of ATl receptor in agonist activation
    • Noda K., Saad Y., Karnik S.S. Interaction of Phe8 of angiotensin II with Lys199 and His256 of ATl receptor in agonist activation. J. Biol. Chem. 270:1995;28511-28514.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28511-28514
    • Noda, K.1    Saad, Y.2    Karnik, S.S.3
  • 16
    • 0029078461 scopus 로고
    • Functional studies but not receptor binding can distinguish surmountable from insurmountable AT1 antagonism
    • Panek R.L., Lu G.H., Overhisser R.W., Major T.C., Hodges J.C., Taylor D.G. Functional studies but not receptor binding can distinguish surmountable from insurmountable AT1 antagonism. J. Pharmacol. Exp. Ther. 273:1995;753-761.
    • (1995) J. Pharmacol. Exp. Ther. , vol.273 , pp. 753-761
    • Panek, R.L.1    Lu, G.H.2    Overhisser, R.W.3    Major, T.C.4    Hodges, J.C.5    Taylor, D.G.6
  • 19
    • 0028149946 scopus 로고
    • Agonist-antagonist interactions at angiotensin receptors: Application of a two-state receptor model
    • Robertson M.J., Dougall I.G., Harper D., Mckechnie K.C.W., Leff P. Agonist-antagonist interactions at angiotensin receptors: application of a two-state receptor model. Trends Pharmacol. Sci. 15:1994;364-369.
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 364-369
    • Robertson, M.J.1    Dougall, I.G.2    Harper, D.3    Mckechnie, K.C.W.4    Leff, P.5
  • 20
    • 0023674735 scopus 로고
    • Deregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase C
    • Seeuwen K., Lagarde A., Pouysségur J. Deregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide-specific phospholipase C. EMBO J. 7:1988;161-168.
    • (1988) EMBO J. , vol.7 , pp. 161-168
    • Seeuwen, K.1    Lagarde, A.2    Pouysségur, J.3
  • 21
    • 0027431141 scopus 로고
    • Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-l-[[2.45-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7- carboxylic acid (CV-11974), and its prodrug, (±)-1-(cyclohexyloxy-carbonyloxy)-ethyl2-ethoxy-1-[[2′-(1H- tetrazol-5-yl)biohenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116)
    • Shibouta Y., Inada Y., Ojima M., Wada T., Noda M., Sanada T., Kubo K., Kohara Y., Naka T., Nishikawa K. Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-l-[[2.45-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7- carboxylic acid (CV-11974), and its prodrug, (±)-1-(cyclohexyloxy-carbonyloxy)-ethyl2-ethoxy-1-[[2′-(1H- tetrazol-5-yl)biohenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116). J. Pharmacol. Exp. Ther. 266:1993;114-120.
    • (1993) J. Pharmacol. Exp. Ther. , vol.266 , pp. 114-120
    • Shibouta, Y.1    Inada, Y.2    Ojima, M.3    Wada, T.4    Noda, M.5    Sanada, T.6    Kubo, K.7    Kohara, Y.8    Naka, T.9    Nishikawa, K.10
  • 26
    • 0025086862 scopus 로고
    • Nonpepride angiotensin receptor antagonists. XI. Pharmacology of EXP3174: An active metabolite of DuP 753, an orally active antihypertensice agent
    • Wong P.C., Price A.W., Chiu A.T., Duncia J.V., Carini D.J., Wexler R., Johnson A., Timmermans P.B.M.W.M. Nonpepride angiotensin receptor antagonists. XI. Pharmacology of EXP3174: An active metabolite of DuP 753, an orally active antihypertensice agent. J. Pharmacol. Exp. Ther. 255:1990;211-217.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 211-217
    • Wong, P.C.1    Price, A.W.2    Chiu, A.T.3    Duncia, J.V.4    Carini, D.J.5    Wexler, R.6    Johnson, A.7    Timmermans, P.B.M.W.M.8
  • 27
    • 0028237228 scopus 로고
    • Different types of angiotensin II receptor antagonism induced by BIBS 222 in the rat portal vein and rabbit aorta; The influence of receptor reserve
    • Zhang J.C., Van Meel A., Pfaffendorf M., Van Zwieten P. Different types of angiotensin II receptor antagonism induced by BIBS 222 in the rat portal vein and rabbit aorta; the influence of receptor reserve. J. Pharmacol. Exp. Ther. 269:1993;509-514.
    • (1993) J. Pharmacol. Exp. Ther. , vol.269 , pp. 509-514
    • Zhang, J.C.1    Van Meel, A.2    Pfaffendorf, M.3    Van Zwieten, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.