Design of 1-arylsulfamido-2-alkylpiperazine derivatives as secreted PLA2 inhibitors

Journal of Molecular Modeling

Volumn 17, Issue 4, 2011, Pages 817-831

  Badrinarayan, Preethi ^a   Srivani, P ^a   Narahari Sastry, G ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

CoMFA; CoMSIA; Design; Docking; Molecular modeling; PLA2

Indexed keywords

1 ARYL SULFAMIDO 2 ALKYL PIPERAZINE DERIVATIVE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PIPERAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; ENZYME INHIBITION; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DOCKING; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATIC ELECTRICITY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CATTLE; COMPUTER SIMULATION; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A2; PIPERAZINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SULFONAMIDES;

BOVINAE;

EID: 79957944746     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-010-0752-2     Document Type: Article

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