SCOPUS 정보 검색 플랫폼

Volumn 36, Issue 1, 2001, Pages 1-19

A molecular modeling and 3D QSAR study of a large series of indole inhibitors of human non-pancreatic secretory phospholipase A2

(4) Bernard, Philippe a,b Pintore, Marco a Berthon, Jean Yves b Chrétien, Jacques R a

a UNIVERSITÉ D'ORLÉANS (France)

b GREENTECH Biotechnologies (France)

Author keywords

3D QSAR; CoMFA; Docking; Human non pancreatic phospholipase; Protein based alignment

Indexed keywords

INDOLE DERIVATIVE; PANCREAS ENZYME; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR;

ARTICLE; CRYSTAL STRUCTURE; ENZYME INHIBITION; HUMAN; MOLECULAR MODEL; PHARMACOPHORE; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTI-INFLAMMATORY AGENTS; COMPUTER SIMULATION; CRYSTALLIZATION; ENZYME INHIBITORS; HUMANS; INDOLES; MODELS, MOLECULAR; PANCREAS; PHOSPHOLIPASES A; PROTEIN CONFORMATION; REPRODUCIBILITY OF RESULTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035111276 PISSN: 02235234 EISSN: None Source Type: Journal
DOI: 10.1016/S0223-5234(00)01183-1 Document Type: Article

Times cited : (27)

References (57)

1
- 0033009017
- (1999) Curr. Opin. Drug Disc. Devel. , vol.2 , pp. 213-223
- Bernard, P.¹ Berthon, J.-Y.² Chrétien, J.R.³

2
- 0019961652
- (1982) Biochem. J. , vol.204 , pp. 3-10
- Irvine, R.F.¹

3
- 0027513175
- (1993) FASEB J. , vol.7 , pp. 339-348
- Mayer, R.J.¹ Marshall, L.A.²

4
- 0025869402
- (1991) FASEB J. , vol.5 , pp. 2068-2077
- Dennis, E.A.¹ Rhee, S.G.² Billah, M.M.³ Hannun, Y.A.⁴

5
- 0025107548
- (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7708-7712
- Clark, J.D.¹ Milona, N.² Knopf, J.L.³

6
- 0024564475
- (1989) J. Biol. Chem. , vol.264 , pp. 5768-5775
- Kramer, R.M.¹ Hession, C.² Johansen, B.³ Hayes, G.⁴ McGray, P.⁵ Chow, E.P.⁶ Tizard, R.⁷ Pepinski, R.B.⁸

7
- 0024588250
- (1989) Biochem. , vol.105 , pp. 395-399
- Hara, S.¹ Kudo, I.² Chang, H.W.³ Matsuta, K.J.⁴

8
- 0024165305
- (1988) Biochem. Biophys. Res. Commun. , vol.157 , pp. 488-493
- Lai, C.-Y.¹ Wada, K.²

9
- 0025765679
- (1991) J. Immunol. , vol.146 , pp. 3904-3910
- Bomalaski, J.S.¹ Lawton, P.² Browning, J.L.³

10
- 0026489529
- (1992) Digestion , vol.52 , pp. 232-236
- Gronroos, J.M.¹ Nevalainen, T.J.²

11
- 0025917869
- (1991) Inflammation , vol.15 , pp. 355-367
- Green, J.A.¹ Smith, G.M.² Buchta, R.³ Lee, R.⁴ Ho, K.Y.⁵ Rajkovic, I.A.⁶ Scott, K.F.⁷

12
- 0028054976
- (1994) Ann. Surg. , vol.219 , pp. 183-192
- Santos, A.A.¹

13
- 0027405595
- (1993) Circ. Shock , vol.39 , pp. 160-167
- Vadas, P.¹ Pruzanski, W.²

14
- 0025196093
- (1990) Trauma J. , vol.30 , pp. 1285-1290
- Uhl, W.¹ Buchler, M.² Nevalainen, T.J.³ Deller, A.⁴ Beger, H.G.⁵

15
- 0026342821
- (1991) Science , vol.254 , pp. 1007-1010
- Scott, D.L.¹ White, S.P.² Browning, J.L.³ Rosa, J.J.⁴ Gelb, M.H.⁵ Sigler, P.B.⁶

16
- 0025882982
- (1991) Nature , vol.352 , pp. 79-82
- Wery, J.P.¹ Schevitz, R.W.² Clawson, D.K.³ Bobbitt, J.L.⁴ Dow, E.R.⁵ Gamboa, G.⁶ Goodson, T.J.R.⁷ Hermann, R.B.⁸ Kramer, R.M.⁹ McClure, D.B.¹⁰

17
- 0029662266
- (1996) J. Med. Chem. , vol.39 , pp. 3878-3881
- Cha, S.S.¹ Lee, D.² Adams, J.³ Kurdyla, J.T.⁴ Jones, C.S.⁵ Marshall, L.A.⁶ Bolognese, B.⁷ Abdel-Meguid, S.S.⁸ Oh, B.H.⁹

18
- 0030300104
- (1996) J. Med. Chem. , vol.39 , pp. 5183-5191
- Teshiro, I.¹ Matsutani, S.² Shirahase, K.³ Fujii, Y.⁴ Yoshida, T.⁵ Tanaka, K.⁶ Ohtani, M.⁷

19
- 0030450411
- (1996) J. Med. Chem. , vol.39 , pp. 5176-5182
- Baba, A.¹ Kawamura, N.² Makino, H.³ Ohta, Y.⁴ Taketomi, S.⁵ Sohda, T.⁶

20
- 0032514469
- (1998) J. Med. Chem. , vol.41 , pp. 3232-3238
- De Rosa, M.¹ Giordano, S.² Scettri, A.³ Sodano, G.⁴ Soriente, A.⁵ Garcia Pastor, P.⁶ Alcaraz, M.J.⁷ Paya, M.⁸

21
- 0026357167
- (1991) Biochemistry , vol.30 , pp. 11801-11811
- Noel, J.P.¹ Bingman, C.A.² Deng, T.L.³ Dupureur, C.M.⁴ Hamilton, K.J.⁵ Jiang, R.T.⁶ Kwak, J.G.⁷ Sekharudu, C.⁸ Sundaralingam, M.⁹ Tsai, M.D.¹⁰

22
- 0026545532
- (1992) Biochemistry , vol.31 , pp. 2887-2896
- Ortiz, A.R.¹ Pisabarro, M.T.² Gallego, J.³ Gago, F.⁴

23
- 0028324779
- (1994) J. Med. Chem. , vol.37 , pp. 337-341
- Pisabarro, M.T.¹ Ortiz, A.R.² Palomer, A.³ Cabre, F.⁴ Garcia, L.⁵ Wade, R.C.⁶ Gago, F.⁷ Mauleon, D.⁸ Carganico, G.⁹

24
- 0026775943
- (1992) J. Med. Chem. , vol.35 , pp. 2939-2951
- Bennion, C.¹ Connoly, S.² Gensmantel, N.P.³ Hallam, C.⁴ Jackson, C.G.⁵ Primrose, W.U.⁶ Roberts, G.C.⁷ Robinson, D.H.⁸ Slaich, P.K.⁹

25
- 0026689363
- (1992) Proteins , vol.14 , pp. 45-64
- Sessions, R.B.¹ Dauber-Osguthorpe, P.² Campbell, M.M.³ Osguthorpe, D.J.⁴

26
- 0030747281
- (1997) Biochim. Biophys. Acta , vol.1340 , pp. 178-186
- Tomoo, K.¹ Yamane, A.² Ishida, T.³ Fujii, S.⁴ Ikeda, K.⁵ Iwama, S.⁶ Katsumura, S.⁷ Sumiya, S.⁸ Miyagawa, H.⁹ Kitamura, K.¹⁰

27
- 0025610265
- (1990) J. Mol. Biol. , vol.216 , pp. 425-439
- Thunnissen, M.M.¹ Kalk, K.H.² Drenth, J.³ Dijkstra, B.W.⁴

28
- 0030111085
- (1996) J. Mol. Recognit. , vol.9 , pp. 95-102
- Hariprasad, V.¹ Kulkarni, V.M.²

29
- 0029000922
- Published erratum appears in additions and corrections, J. Med. Chem. 40 (1997) 4168
- (1995) J. Med. Chem. , vol.38 , pp. 2681-2691
- Ortiz, A.R.¹ Pisabarro, M.T.² Gago, F.³ Wade, R.C.⁴

30
- 0030892498
- (1997) J. Med. Chem. , vol.40 , pp. 1136-1148
- Ortiz, A.R.¹ Pastor, M.² Palomer, A.³ Cruciani, G.⁴ Gago, F.⁵ Wade, R.C.⁶

31
- 0001016942
- (1994) Acc. Chem. Res. , vol.27 , pp. 117-123
- Kuntz, I.D.¹ Meng, E.C.² Shoichet, B.K.³

32
- 0023751431
- (1988) J. Amer. Chem. Soc. , vol.110 , pp. 5959-5967
- Cramer III, R.D.¹ Patterson, D.E.² Bunce, J.D.³

33
- 0025608353
- (1990) Science , vol.250 , pp. 1560-1563
- White, S.P.¹ Scott, D.L.² Otwinowski, Z.³ Gelb, M.H.⁴ Sigler, P.B.⁵

34
- 0025668794
- (1990) Science , vol.250 , pp. 1563-1566
- Scott, D.L.¹ Otwinowski, Z.² Gelb, M.H.³ Sigler, P.B.⁴

35
- 0026357167
- (1991) Biochemistry , vol.30 , pp. 11801-11811
- Noel, J.P.¹ Bingman, C.A.² Deng, T.L.³ Dupureur, C.M.⁴ Hamilton, K.J.⁵ Jiang, R.T.⁶ Kwak, J.G.⁷ Sekharudu, C.⁸ Sundaralingam, M.⁹ Tsai, M.D.¹⁰

36
- 0025027265
- (1990) Nature , vol.347 , pp. 689-691
- Thunnissen, M.M.¹ Ab, E.² Kalk, K.H.³ Drenth, J.⁴ Dijkstra, B.W.⁵ Kuipers, O.P.⁶ Dijkman, R.⁷ De Haas, G.H.⁸ Verheij, H.M.⁹

37
- 0005933692
- (31 July 95, PDB code: 1AYP). To be published
- Oh, B.-H.¹

38
- 0005960679
- 1699 South Hanley Road, St Louis, MO 63144

39
- 84988115618
- (1989) J. Comput. Chem. , vol.10 , pp. 982-1012
- Clark, M.¹ Cramer III, R.D.² Opdenbosch, N.V.³

40
- 0028997717
- (1995) Nat. Struct. Biol. , vol.2 , pp. 458-465
- Schevitz, R.W.¹ Bach, N.J.² Carlson, D.G.³ Chirgadze, N.Y.⁴ Clawson, D.K.⁵ Dillard, R.D.⁶ Draheim, S.E.⁷ Hartley, L.W.⁸ Jones, N.D.⁹ Mihelich, E.D.¹⁰ Olkowski, J.L.¹¹ Snyder, D.W.¹² Sommers, C.¹³ Wery, J.-P.¹⁴

41
- 0032812604
- (1999) J. Comput.-Aided Mol. Des. , vol.13 , pp. 355-371
- Bernard, P.¹ Kireev, D.B.² Chretien, J.R.³ Fortier, P.-L.⁴ Coppet, L.⁵

42
- 12644258541
- (1996) J. Med. Chem. , vol.39 , pp. 5119-5136
- Dillard, R.D.¹ Bach, N.J.² Draheim, S.E.³ Berry, D.R.⁴ Carlson, D.G.⁵ Chirgadze, N.Y.⁶ Clawson, D.K.⁷ Hartley, L.W.⁸ Johnson, L.M.⁹ Jones, N.D.¹⁰ McKinney, E.R.¹¹ Mihelich, E.D.¹² Olkowski, J.L.¹³ Schevitz, R.W.¹⁴ Smith, A.C.¹⁵ Snyder, D.W.¹⁶ Sommers, C.D.¹⁷ Wery, J.-P.¹⁸

43
- 12644249111
- (1996) J. Med. Chem. , vol.39 , pp. 5137-5158
- Dillard, R.D.¹ Bach, N.J.² Draheim, S.E.³ Berry, D.R.⁴ Carlson, D.G.⁵ Chirgadze, N.Y.⁶ Clawson, D.K.⁷ Hartley, L.W.⁸ Johnson, L.M.⁹ Jones, N.D.¹⁰ McKinney, E.R.¹¹ Mihelich, E.D.¹² Olkowski, J.L.¹³ Schevitz, R.W.¹⁴ Smith, A.C.¹⁵ Snyder, D.W.¹⁶ Sommers, C.D.¹⁷ Wery, J.-P.¹⁸

44
- 12644262408
- (1996) J. Med. Chem. , vol.39 , pp. 5159-5175
- Draheim, S.E.¹ Bach, N.J.² Dillard, R.D.³ Berry, D.R.⁴ Carlson, D.G.⁵ Chirgadze, N.Y.⁶ Clawson, D.K.⁷ Hartley, L.W.⁸ Johnson, L.M.⁹ Jones, N.D.¹⁰ McKinney, E.R.¹¹ Mihelich, E.D.¹² Olkowski, J.L.¹³ Schevitz, R.W.¹⁴ Smith, A.C.¹⁵ Snyder, D.W.¹⁶ Sommers, C.D.¹⁷ Wery, J.-P.¹⁸

45
- 0026723388
- (1992) Anal. Biochem. , vol.204 , pp. 190-197
- Reynolds, L.J.¹ Hughes, L.L.² Dennis, E.A.³

46
- 0003527079
- Springer-Verlag, Berlin
- (1988) Self-Organization and Associative Memory
- Kohonen, T.¹

47
- 0032450993
- (1998) Analusis , vol.26 , pp. 333-341
- Bernard, P.¹ Golbraikh, A.² Kireev, D.B.³ Chrétien, J.R.⁴ Rozhkova, N.⁵

48
- 0003816887
- John Wiley and Sons, New York
- (1986) Molecular Connectivity in Structure-Activity Analysis
- Kier, L.B.¹ Hall, L.H.²

49
- 36749120371
- (1975) J. Chem. Phys. , vol.62 , pp. 3339-3405
- Gutman, I.¹ Ruscic, B.² Trinajstic, N.³ Wilcox C.F., Jr.⁴

50
- 0002068022
- Karcher W., Devillers J. (Eds.), Practical Applications of Quantitative Structure-Activity Relationships (QSAR) in Environmental Chemistry and toxicology. Kluwer Academic Publishers, Dordrecht
- (1990) , pp. 61-82
- Sabljic, A.¹

51
- 0005968726
- Karcher W., Devillers J. (Eds.), Practical Applications of Quantitative Structure-Activity Relationships (QSAR) in Environmental Chemistry and Toxicology, Kluwer Academic Publishers, Dordrecht
- (1990) , pp. 83-103
- Sabljic, A.¹

52
- 0003879901
- Wiley Interscience Publications
- (1979) Substituent Constants for Correlation Analysis in Chemistry and Biology , pp. 13
- Hansch, C.¹ Leo, A.²

53
- 0003890065
- Academic Press, New York
- (1976) Chemical Bonds and Bond Energy
- Sanderson, R.T.¹

54
- 0842341771
- (1985) J. Amer. Chem. Soc. , vol.107 , pp. 3902-3909
- Dewar, M.J.S.¹ Zoebich, E.G.² Healy, E.F.³ Stewart, J.J.P.⁴

55
- 0000295654
- Waterbeemd H. (Ed.), Chemometric Methods in Molecular Design, VCH, Weinheim
- (1995) , pp. 309-318
- Wold, S.¹ Eriksson, L.²

56
- 0028024830
- (1994) Biophys. J. , vol.67 , pp. 493-504
- Scott, D.L.¹ Mandel, A.M.² Sigler, P.B.³ Honig, B.⁴

57
- 0005964113
- Waterbeemd H. (Ed.), Chemometric Methods in Molecular Design, VCH, Weinheim
- (1995) , pp. 324-325
- Clementi, S.¹ Wold, S.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.