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Volumn 3, Issue 2, 2011, Pages 206-215

Emerging clinical applications in cardiovascular pharmacogenomics

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR AGENT; HEMATOLOGIC AGENT;

EID: 79957934004     PISSN: 19395094     EISSN: 1939005X     Source Type: Journal    
DOI: 10.1002/wsbm.113     Document Type: Review
Times cited : (7)

References (65)
  • 2
    • 69249219295 scopus 로고    scopus 로고
    • Tailoring antiplatelet therapy based on pharmacogenomics: how well do the data fit?
    • Bhatt DL. Tailoring antiplatelet therapy based on pharmacogenomics: how well do the data fit?. JAMA 2009, 302:896-897.
    • (2009) JAMA , vol.302 , pp. 896-897
    • Bhatt, D.L.1
  • 3
    • 58749095297 scopus 로고    scopus 로고
    • Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillation
    • Eckman MH, Rosand J, Greenberg SM, Gage BF. Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillation. Ann Intern Med2009, 150:73-83.
    • (2009) Ann Intern Med , vol.150 , pp. 73-83
    • Eckman, M.H.1    Rosand, J.2    Greenberg, S.M.3    Gage, B.F.4
  • 4
    • 60849115571 scopus 로고    scopus 로고
    • Pharmacogenetics-tailoring treatment for the outliers
    • Woodcock J, Lesko LJ. Pharmacogenetics-tailoring treatment for the outliers. N Eng J Med2009, 360:811-813.
    • (2009) N Eng J Med , vol.360 , pp. 811-813
    • Woodcock, J.1    Lesko, L.J.2
  • 5
    • 3142706539 scopus 로고    scopus 로고
    • Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease
    • Song Y, Stampfer MJ, Liu S. Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease. Ann Intern Med 2004, 141:137-147.
    • (2004) Ann Intern Med , vol.141 , pp. 137-147
    • Song, Y.1    Stampfer, M.J.2    Liu, S.3
  • 6
    • 34247144499 scopus 로고    scopus 로고
    • Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
    • Morgan TM, Krumholz HM, Lifton RP, Spertus JA. Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. JAMA 2007, 297:1551-1561.
    • (2007) JAMA , vol.297 , pp. 1551-1561
    • Morgan, T.M.1    Krumholz, H.M.2    Lifton, R.P.3    Spertus, J.A.4
  • 7
    • 55449120805 scopus 로고    scopus 로고
    • Genetic mapping in human disease
    • Altshuler D, Daly MJ, Lander ES. Genetic mapping in human disease. Science 2008, 322:881-888.
    • (2008) Science , vol.322 , pp. 881-888
    • Altshuler, D.1    Daly, M.J.2    Lander, E.S.3
  • 8
    • 35748959936 scopus 로고    scopus 로고
    • Future use of genomics in coronary artery disease
    • Damani SB, Topol EJ. Future use of genomics in coronary artery disease. J Am Coll Cardiol 2007, 50:1933-1940.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1933-1940
    • Damani, S.B.1    Topol, E.J.2
  • 9
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • Frazer KA, Ballinger DG, Cox DR, et al. A second generation human haplotype map of over 3.1 million SNPs. Nature 2007, 449:851-861.
    • (2007) Nature , vol.449 , pp. 851-861
    • Frazer, K.A.1    Ballinger, D.G.2    Cox, D.R.3
  • 10
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
    • Shuldiner AR, O'Connell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA 2009, 302:849-857.
    • (2009) JAMA , vol.302 , pp. 849-857
    • Shuldiner, A.R.1    O'Connell, J.R.2    Bliden, K.P.3
  • 11
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy-a genomewide study
    • Link E, Parish S, Armitage J, et al. SLCO1B1 variants and statin-induced myopathy-a genomewide study. N Eng J Med 2008, 359:789-799.
    • (2008) N Eng J Med , vol.359 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3
  • 12
    • 70649113052 scopus 로고    scopus 로고
    • Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy
    • Ross CJ, Katzov-Eckert H, Dube MP, et al. Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. Nat Genet 2009, 41:1345-1349.
    • (2009) Nat Genet , vol.41 , pp. 1345-1349
    • Ross, C.J.1    Katzov-Eckert, H.2    Dube, M.P.3
  • 13
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009, 461:399-401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 14
    • 67649859295 scopus 로고    scopus 로고
    • HLA- B*5701 genotype is a major determinant of drug- induced liver injury due to flucloxacillin
    • Daly AK, Donaldson PT, Bhatnagar P, et al. HLA- B*5701 genotype is a major determinant of drug- induced liver injury due to flucloxacillin. Nat Genet 2009, 41:816-819.
    • (2009) Nat Genet , vol.41 , pp. 816-819
    • Daly, A.K.1    Donaldson, P.T.2    Bhatnagar, P.3
  • 15
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009, 461:747-753.
    • (2009) Nature , vol.461 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 16
    • 0035908781 scopus 로고    scopus 로고
    • Effects of pre-treatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study
    • Mehta SR, Yusuf S, Peters RJ, et al. Effects of pre-treatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet 2001, 358:527-533.
    • (2001) Lancet , vol.358 , pp. 527-533
    • Mehta, S.R.1    Yusuf, S.2    Peters, R.J.3
  • 17
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Eng J Med 2001, 345: 494-502.
    • (2001) N Eng J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 18
    • 0037145863 scopus 로고    scopus 로고
    • Early and sustained dual oral antiplatelet therapy following percu- taneous coronary intervention: a randomized controlled trial
    • Steinhubl SR, Berger PB, Mann JT III, et al. Early and sustained dual oral antiplatelet therapy following percu- taneous coronary intervention: a randomized controlled trial. JAMA 2002, 288:2411-2420.
    • (2002) JAMA , vol.288 , pp. 2411-2420
    • Steinhubl, S.R.1    Berger, P.B.2    Mann III, J.T.3
  • 19
    • 33749339075 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
    • Hulot JS, Bura A, Villard E, et al. Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects. Blood 2006, 108:2244-2247.
    • (2006) Blood , vol.108 , pp. 2244-2247
    • Hulot, J.S.1    Bura, A.2    Villard, E.3
  • 20
    • 58249135635 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study
    • Collet JP, Hulot JS, Pena A, et al. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study. Lancet 2009, 373:309-317.
    • (2009) Lancet , vol.373 , pp. 309-317
    • Collet, J.P.1    Hulot, J.S.2    Pena, A.3
  • 21
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Eng J Med 2009, 360:354-362.
    • (2009) N Eng J Med , vol.360 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 22
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • Simon T, Verstuyft C, Mary-Krause M, et al. Genetic determinants of response to clopidogrel and cardiovascular events. N Eng J Med2009, 360:363-375.
    • (2009) N Eng J Med , vol.360 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 23
    • 76349098199 scopus 로고    scopus 로고
    • Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    • Sibbing D, Koch W, Gebhard D, et al. Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation 121:512-518.
    • Circulation , vol.121 , pp. 512-518
    • Sibbing, D.1    Koch, W.2    Gebhard, D.3
  • 24
    • 58149476444 scopus 로고    scopus 로고
    • Tailored clopidogrel loading dose according to platelet reactivity monitoring to prevent acute and subacute stent thrombosis
    • Bonello L, Camoin-Jau L, Armero S, et al. Tailored clopidogrel loading dose according to platelet reactivity monitoring to prevent acute and subacute stent thrombosis. Am J Cardiol 2009, 103:5-10.
    • (2009) Am J Cardiol , vol.103 , pp. 5-10
    • Bonello, L.1    Camoin-Jau, L.2    Armero, S.3
  • 25
    • 79960295733 scopus 로고    scopus 로고
    • Current Oasis-7: benefit to doubling clopidogrel dose in acute coronary syndrome patients undergoing percutaneous coronary intervention
    • Mehta SR. Current Oasis-7: benefit to doubling clopidogrel dose in acute coronary syndrome patients undergoing percutaneous coronary intervention. Eur Soc Cong 2009.
    • (2009) Eur Soc Cong
    • Mehta, S.R.1
  • 26
    • 36148983750 scopus 로고    scopus 로고
    • Prasugrel versus clopidogrel in patients with acute coronary syndromes
    • Wiviott SD, Braunwald E, McCabe CH, et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Eng J Med2007, 357:2001-2015.
    • (2007) N Eng J Med , vol.357 , pp. 2001-2015
    • Wiviott, S.D.1    Braunwald, E.2    McCabe, C.H.3
  • 27
    • 70149101223 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with acute coronary syndromes
    • Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Eng J Med 2009, 361:1045-1057.
    • (2009) N Eng J Med , vol.361 , pp. 1045-1057
    • Wallentin, L.1    Becker, R.C.2    Budaj, A.3
  • 28
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Lloyd-Jones D, Adams R, Carnethon M, et al. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009, 119:480-486.
    • (2009) Circulation , vol.119 , pp. 480-486
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3
  • 29
    • 34447306023 scopus 로고    scopus 로고
    • Bleeding compli- cations with warfarin use: a prevalent adverse effect resulting in regulatory action
    • Wysowski DK, Nourjah P, Swartz L. Bleeding compli- cations with warfarin use: a prevalent adverse effect resulting in regulatory action. Arch Intern Med 2007, 167:1414-1419.
    • (2007) Arch Intern Med , vol.167 , pp. 1414-1419
    • Wysowski, D.K.1    Nourjah, P.2    Swartz, L.3
  • 30
    • 0035128589 scopus 로고    scopus 로고
    • Hemorrhagic complications of anticoagulant treatment
    • Levine MN, Raskob G, Landefeld S, Kearon C. Hemorrhagic complications of anticoagulant treatment. Chest 2001, 119:108S-121S.
    • (2001) Chest , vol.119
    • Levine, M.N.1    Raskob, G.2    Landefeld, S.3    Kearon, C.4
  • 31
    • 72949112021 scopus 로고    scopus 로고
    • Warfarin sensitivity genotyping: a review of the literature and summary of patient experience
    • Moyer TP, O'Kane DJ, Baudhuin LM, et al. Warfarin sensitivity genotyping: a review of the literature and summary of patient experience. Mayo Clin Proc 2009, 84:1079-1094.
    • (2009) Mayo Clin Proc , vol.84 , pp. 1079-1094
    • Moyer, T.P.1    O'Kane, D.J.2    Baudhuin, L.M.3
  • 32
    • 21144448879 scopus 로고    scopus 로고
    • Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
    • Rieder MJ, Reiner AP, Gage BF, et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N Eng J Med2005, 352:2285-2293.
    • (2005) N Eng J Med , vol.352 , pp. 2285-2293
    • Rieder, M.J.1    Reiner, A.P.2    Gage, B.F.3
  • 33
    • 60849097257 scopus 로고    scopus 로고
    • Estimation of the warfarin dose with clinical and pharmacogenetic data
    • Klein TE, Altman RB, Eriksson N, et al. Estimation of the warfarin dose with clinical and pharmacogenetic data. N Eng J Med2009, 360:753-764.
    • (2009) N Eng J Med , vol.360 , pp. 753-764
    • Klein, T.E.1    Altman, R.B.2    Eriksson, N.3
  • 34
    • 77953304931 scopus 로고    scopus 로고
    • Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo warfarin effectiveness study)
    • Epstein RS, Moyer TP, Aubert RE, et al. Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo warfarin effectiveness study). J Am Coll Cardiol.
    • J Am Coll Cardiol
    • Epstein, R.S.1    Moyer, T.P.2    Aubert, R.E.3
  • 35
    • 34548575058 scopus 로고    scopus 로고
    • Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial
    • Eriksson BI, Dahl OE, Rosencher N, et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 2007, 370:949-956.
    • (2007) Lancet , vol.370 , pp. 949-956
    • Eriksson, B.I.1    Dahl, O.E.2    Rosencher, N.3
  • 36
    • 0037418250 scopus 로고    scopus 로고
    • Antiadrenergic therapy of chronic heart failure: surprises and new opportunities
    • Bristow M. Antiadrenergic therapy of chronic heart failure: surprises and new opportunities. Circulation 2003, 107:1100-1102.
    • (2003) Circulation , vol.107 , pp. 1100-1102
    • Bristow, M.1
  • 37
    • 0034620523 scopus 로고    scopus 로고
    • Beta-adrenergic receptor blockade in chronic heart failure
    • Bristow MR. Beta-adrenergic receptor blockade in chronic heart failure. Circulation 2000, 101:558-569.
    • (2000) Circulation , vol.101 , pp. 558-569
    • Bristow, M.R.1
  • 39
    • 0038408846 scopus 로고    scopus 로고
    • Efficacy of angiotensin-converting enzyme inhibitors and beta- blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status: a meta-analysis of major clinical trials
    • Shekelle PG, Rich MW, Morton SC, et al. Efficacy of angiotensin-converting enzyme inhibitors and beta- blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status: a meta-analysis of major clinical trials. J Am Coll Cardiol 2003, 41:1529-1538.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 1529-1538
    • Shekelle, P.G.1    Rich, M.W.2    Morton, S.C.3
  • 40
    • 33746603033 scopus 로고    scopus 로고
    • A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure
    • Liggett SB, Mialet-Perez J, Thaneemit-Chen S, et al. A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci USA 2006, 103:11288-11293.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11288-11293
    • Liggett, S.B.1    Mialet-Perez, J.2    Thaneemit-Chen, S.3
  • 41
    • 43249124512 scopus 로고    scopus 로고
    • A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure
    • Liggett SB, Cresci S, Kelly RJ, et al. A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure. Nat Med 2008, 14:510-517.
    • (2008) Nat Med , vol.14 , pp. 510-517
    • Liggett, S.B.1    Cresci, S.2    Kelly, R.J.3
  • 42
    • 0037223063 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization
    • Kohout TA, Lefkowitz RJ. Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization. Mol Pharmacol 2003, 63:9-18.
    • (2003) Mol Pharmacol , vol.63 , pp. 9-18
    • Kohout, T.A.1    Lefkowitz, R.J.2
  • 43
    • 0026514988 scopus 로고
    • Modulation of plasma triglyceride levels by apoE phenotype: a meta-analysis
    • Dallongeville J, Lussier-Cacan S, Davignon J. Modulation of plasma triglyceride levels by apoE phenotype: a meta-analysis. J Lipid Res 1992, 33:447-454.
    • (1992) J Lipid Res , vol.33 , pp. 447-454
    • Dallongeville, J.1    Lussier-Cacan, S.2    Davignon, J.3
  • 44
    • 0032866820 scopus 로고    scopus 로고
    • Apolipoprotein E and atherosclerosis: insight from animal and human studies
    • Davignon J, Cohn JS, Mabile L, Bernier L. Apolipoprotein E and atherosclerosis: insight from animal and human studies. Clin Chim Acta 1999, 286:115-143.
    • (1999) Clin Chim Acta , vol.286 , pp. 115-143
    • Davignon, J.1    Cohn, J.S.2    Mabile, L.3    Bernier, L.4
  • 46
    • 0034078501 scopus 로고    scopus 로고
    • Genetic determinants of plasma lipid response to dietary intervention: the role of the APOA1/C3/A4 gene cluster and the APOE gene
    • Ordovas JM, Schaefer EJ. Genetic determinants of plasma lipid response to dietary intervention: the role of the APOA1/C3/A4 gene cluster and the APOE gene. Br J Nutr 2000, 83:S127-S136.
    • (2000) Br J Nutr , vol.83
    • Ordovas, J.M.1    Schaefer, E.J.2
  • 47
    • 0023860891 scopus 로고
    • Apolipoprotein E polymorphism and atherosclerosis
    • Davignon J, Gregg RE, Sing CF. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 1988, 8:1-21.
    • (1988) Arteriosclerosis , vol.8 , pp. 1-21
    • Davignon, J.1    Gregg, R.E.2    Sing, C.F.3
  • 48
    • 58149163149 scopus 로고    scopus 로고
    • Common variants at 30 loci contribute to polygenic dyslipidemia
    • Kathiresan S, Willer CJ, Peloso GM, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet 2009, 41:56-65.
    • (2009) Nat Genet , vol.41 , pp. 56-65
    • Kathiresan, S.1    Willer, C.J.2    Peloso, G.M.3
  • 49
    • 0034724089 scopus 로고    scopus 로고
    • The apolipo- protein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction: a substudy of the Scandinavian simvastatin survival study
    • Gerdes LU, Gerdes C, Kervinen K, et al. The apolipo- protein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction: a substudy of the Scandinavian simvastatin survival study. Circulation 2000, 101:1366-1371.
    • (2000) Circulation , vol.101 , pp. 1366-1371
    • Gerdes, L.U.1    Gerdes, C.2    Kervinen, K.3
  • 50
    • 38349130543 scopus 로고    scopus 로고
    • A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study
    • Shiffman D, Chasman DI, Zee RY, et al. A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study. J Am Coll Cardiol 2008, 51:444-448.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 444-448
    • Shiffman, D.1    Chasman, D.I.2    Zee, R.Y.3
  • 51
    • 38349118892 scopus 로고    scopus 로고
    • Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials
    • Iakoubova OA, Tong CH, Rowland CM, et al. Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials. J Am Coll Cardiol 2008, 51:435-443.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 435-443
    • Iakoubova, O.A.1    Tong, C.H.2    Rowland, C.M.3
  • 52
    • 38349171836 scopus 로고    scopus 로고
    • Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE ITTIMI 22 study
    • Iakoubova OA, Sabatine MS, Rowland CM, et al. Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE ITTIMI 22 study. J Am Coll Cardiol 2008, 51:449-455.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 449-455
    • Iakoubova, O.A.1    Sabatine, M.S.2    Rowland, C.M.3
  • 53
    • 79960333929 scopus 로고    scopus 로고
    • Berkely HeartLab Inc
    • Statin Check. Berkely HeartLab Inc.; 2009.
    • (2009) Statin Check
  • 54
    • 84969213492 scopus 로고    scopus 로고
    • Genomewide association study of 14,000 cases of seven common diseases and 3000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genomewide association study of 14,000 cases of seven common diseases and 3000 shared controls. Nature 2007, 447:661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 55
    • 4143098058 scopus 로고    scopus 로고
    • A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD study
    • Hauser ER, Crossman DC, Granger CB, et al. A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD study. Am J Hum Genet 2004, 75:436-47.
    • (2004) Am J Hum Genet , vol.75 , pp. 436-447
    • Hauser, E.R.1    Crossman, D.C.2    Granger, C.B.3
  • 56
    • 34250010480 scopus 로고    scopus 로고
    • A common variant on chromosome 9p21 affects the risk of myocardial infarction
    • Helgadottir A, Thorleifsson G, Manolescu A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 2007, 316:1491-1493.
    • (2007) Science , vol.316 , pp. 1491-1493
    • Helgadottir, A.1    Thorleifsson, G.2    Manolescu, A.3
  • 57
    • 38649132270 scopus 로고    scopus 로고
    • Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
    • Kathiresan S, Melander O, Guiducci C, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008, 40:189-197.
    • (2008) Nat Genet , vol.40 , pp. 189-197
    • Kathiresan, S.1    Melander, O.2    Guiducci, C.3
  • 58
    • 34249996115 scopus 로고    scopus 로고
    • A common allele on chromosome 9 associated with coronary heart disease
    • McPherson R, Pertsemlidis A, Kavaslar N, et al. A common allele on chromosome 9 associated with coronary heart disease. Science 2007, 316:1488-1491.
    • (2007) Science , vol.316 , pp. 1488-1491
    • McPherson, R.1    Pertsemlidis, A.2    Kavaslar, N.3
  • 59
    • 34547623750 scopus 로고    scopus 로고
    • Genomewide association analysis of coronary artery disease
    • Samani NJ, Erdmann J, Hall AS, et al. Genomewide association analysis of coronary artery disease. N Eng J Med2007, 357:443-453.
    • (2007) N Eng J Med , vol.357 , pp. 443-453
    • Samani, N.J.1    Erdmann, J.2    Hall, A.S.3
  • 60
    • 61349177857 scopus 로고    scopus 로고
    • New susceptibility locus for coronary artery disease on chromosome 3q22.3
    • Erdmann J, Grosshennig A, Braund PS, et al. New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet 2009, 41:280-282.
    • (2009) Nat Genet , vol.41 , pp. 280-282
    • Erdmann, J.1    Grosshennig, A.2    Braund, P.S.3
  • 61
    • 70749096913 scopus 로고    scopus 로고
    • Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
    • Kathiresan S, Voight BF, Purcell S, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet 2009, 41:334-341.
    • (2009) Nat Genet , vol.41 , pp. 334-341
    • Kathiresan, S.1    Voight, B.F.2    Purcell, S.3
  • 62
    • 38349166997 scopus 로고    scopus 로고
    • Surprises of the genome and "personalized" medicine
    • Marian AJ. Surprises of the genome and "personalized" medicine. J Am Coll Cardiol 2008, 51:456-458.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 456-458
    • Marian, A.J.1
  • 63
    • 44049105242 scopus 로고    scopus 로고
    • Association of the 719Arg variant of KIF6 with both increased risk of coronary events and with greater response to statin therapy
    • Iakoubova O, Shepherd J, Sacks F. Association of the 719Arg variant of KIF6 with both increased risk of coronary events and with greater response to statin therapy. J Am Coll Cardiol 2008, 51:2195-2196.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 2195-2196
    • Iakoubova, O.1    Shepherd, J.2    Sacks, F.3
  • 65
    • 70349739250 scopus 로고    scopus 로고
    • The SLCO1B1*5 genetic variant is associated with statin-induced side effects
    • Voora D, Shah SH, Spasojevic I, et al. The SLCO1B1*5 genetic variant is associated with statin-induced side effects. J Am Coll Cardiol 2009, 54:1609-1616.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1609-1616
    • Voora, D.1    Shah, S.H.2    Spasojevic, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.