Online magnetic bead based dynamic protein affinity selection coupled to LC-MS for the screening of acetylcholine binding protein ligands

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 20, 2011, Pages 1781-1788

  Pochet, Lionel ^a   Heus, Ferry ^a   Jonker, Niels ^a   Lingeman, Henk ^a   Smit, August B ^a   Niessen, Wilfried M A ^a   Kool, Jeroen ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Acetylcholine binding protein (AChBP); Affinity selection mass spectrometry; Ligand chromatography; Magnetic beads; Screening assay

Indexed keywords

ACETYLCHOLINE-BINDING PROTEINS; AFFINITY SELECTION; DENATURING SOLUTIONS; DYNAMIC PROTEINS; MAGNETIC BEADS; PARAMAGNETIC BEADS; POTENTIAL LIGAND; PURE COMPOUNDS; SCREENING ASSAY; SPE-LC-MS; TARGET PROTEINS;

BINDERS; CHROMATOGRAPHY; COBALT; COBALT COMPOUNDS; COMPLEXATION; MASS SPECTROMETRY; PARAMAGNETISM; PROTEINS;

LIGANDS;

ACETYLCHOLINE BINDING PROTEIN; BINDING PROTEIN; COBALT; PEPTIDE LIBRARY; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; ELUTION; INCUBATION TEMPERATURE; LIQUID CHROMATOGRAPHY; MAGNETISM; MASS SPECTROMETRY; METHODOLOGY; NONHUMAN; ONLINE ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DENATURATION; SOLID PHASE EXTRACTION; SOLUTION AND SOLUBILITY;

CARRIER PROTEINS; CHROMATOGRAPHY, LIQUID; DRUG DISCOVERY; EQUIPMENT DESIGN; MAGNETICS; MASS SPECTROMETRY; MICROSPHERES; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; SOLID PHASE EXTRACTION;

EID: 79957867345     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.04.023     Document Type: Article

References (24)

1. de Boer A.R., Lingeman H., Niessen W.M.A., Irth H. TrAC, Trends Anal. Chem. 2007, 26:867.
2. Deng G., Sanyal G. J. Pharm. Biomed. Anal 2006, 40:528.
3. Wanner K., Höfner G. Methods and Principles in Medicinal Chemistry 2007, 437. Willey-VCH. R. Mannhold, H. Kubinyi, G. Folkers (Eds.).
4. Jonker N., Kretschmer A., Kool J., Fernandez A., Kloos D., Krabbe J.G., Lingeman H., Irth H. Anal. Chem. 2009, 81:4263.
5. Comess K.M., Schurdak M.E., Voorbach M.J., Coen M., Trumbull J.D., Yang H., Gao L., Tang H., Cheng X., Lerner C.G., McCall J.O., Burns D.J., Beutel B.A. J. Biomol. Screen. 2006, 11:743.
6. Choi Y., Jermihov K., Nam S.J., Sturdy M., Maloney K., Qiu X., Chadwick L.R., Main M., Chen S.N., Mesecar A.D., Farnsworth N.R., Pauli G.F., Fenical W., Pezzuto J.M., van Breemen R.R. Anal. Chem. 2011, 83:1084.
7. Annis D.A., Athanasopoulos J., Curran P.J., Felsch J.S., Kalghatgi K., Lee W.H., Nash H.M., Orminati J.P.A., Rosner K.E., Shipps G.W., Thaddupathy G.R.A., Tyler A.N., Vilenchik L., Wagner C.R., Wintner E.A. Int. J. Mass Spectrom. 2004, 238:77.
8. Moy F.J., Haraki K., Mobilio D., Walker G., Powers R., Tabei K., Tong H., Siegel M.M. Anal. Chem. 2001, 73:571.
9. Siegel M.M., Tabei K., Bebernitz G.A., Baum E.Z. J. Mass Spectrom. 1998, 33:264.
10. Annis D.A., Nickbarg E., Yang X., Ziebell M.R., Whitehurst C.E. Curr. Opin. Chem. Biol. 2007, 11:518.
11. Vu H., Pham N.B., Quinn R.J. J. Biomol. Screen. 2008, 13:265.
12. Moaddel R., Wainer I.W. Nat. Protoc. 2009, 4:197.
13. Besanger T.R., Hodgson R.J., Guillon D., Brennan J.D. Anal. Chim. Acta 2006, 561:107.
14. Calleri E., Ceruti S., Cristalli G., Martini C., Temporini C., Parravicini C., Volpini R., Daniele S., Caccialanza G., Lecca D., Lambertucci C., Trincavelli M.L., Marucci G., Wainer I.W., Ranghino G., Fantucci P., Abbracchio M.P., Massolini G. J. Med. Chem. 2010, 53:3489.
15. Krugmann S., Anderson K.E., Ridley S.H., Risso N., McGregor A., Coadwell J., Davidson K., Eguinoa A., Ellson C.D., Lipp P., Manifava M., Ktistakis N., Painter G., Thuring J.W., Cooper M.A., Lim Z.Y., Holmes A.B., Dove S.K., Michell R.H., Grewal A., Nazarian A., Erdjument-Bromage H., Tempst P., Stephens L.R., Hawkins P.T. Mol. Cell 2002, 9:95.
16. Jonker N., Kool J., Krabbe J.G., Retra K., Lingeman H., Irth H. J. Chromatogr. A 2008, 1205:71.
17. Smit A.B., Brejc K., Syed N., Sixma T.K. Ann. N.Y. Acad. Sci. 2003, 998:81.
18. Celie P.H., Kasheverov I.E., Mordvintsev D.Y., Hogg R.C., van Nierop P., van Elk R., van Rossum-Fikkert S.E., Zhmak M.N., Bertrand D., Tsetlin V., Sixma T.K., Smit A.B. Nat. Struct. Mol. Biol. 2005, 12:582.
19. Brejc K., van Dijk W.J., Klaassen R.V., Schuurmans M., van Der Oost J., Smit A.B., Sixma T.K. Nature 2001, 411:269.
20. Kool J., de Kloe G.E., Bruyneel B., de Vlieger J.S., Retra K., Wijtmans M., van Elk R., Smit A.B., Leurs R., Lingeman H., de Esch I.J., Irth H. J. Med. Chem. 2010, 53:4720.
21. Hogg R.C., Bertrand D. Curr. Drug Target. 2004, 3:123.
22. Hogg R.C., Raggenbass M., Bertrand D. Rev. Physiol. Biochem. Pharmacol. 2003, 147:1.
23. Dutertre S., Ulens C., Buttner R., Fish A., van Elk R., Kendel Y., Hopping G., Alewood P.F., Schroeder C., Nicke A., Smit A.B., Sixma T.K., Lewis R.J. EMBO J. 2007, 26:3858.
24. Shou W.Z., Naidong W. J. Chromatogr. B 2005, 825:186.