Mass spectrometry-based biochemical assays for enzyme-inhibitor screening

TrAC - Trends in Analytical Chemistry

Volumn 26, Issue 9, 2007, Pages 867-883

  de Boer, Arjen R ^a   Lingeman, Henk ^a   Niessen, Wilfried M A ^a   Irth, Hubertus ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Activity screening; Drug discovery; Enzyme assay; Inhibitor screening; Mass spectrometry

Indexed keywords

AFFINITY CHROMATOGRAPHY; DRUG PRODUCTS; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETRY;

ACTIVITY SCREENING; DRUG DISCOVERY; ENZYME ASSAY; INHIBITOR SCREENING;

BIOASSAY;

ENZYME INHIBITOR;

AFFINITY CHROMATOGRAPHY; ARTICLE; DISSOCIATION; ENZYME ASSAY; ENZYME IMMOBILIZATION; FLOW INJECTION ANALYSIS; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; ULTRAFILTRATION;

EID: 34948815190     PISSN: 01659936     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trac.2007.08.004     Document Type: Article

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