Adipose-derived stromal cell autologous transplantation ameliorates pulmonary arterial hypertension induced by shunt flow in rat models

Stem Cells and Development

Volumn 20, Issue 6, 2011, Pages 1001-1010

  Liu, Kai ^a   Liu, Ruifang ^a   Cao, Guangqing ^a   Sun, Hourong ^a   Wang, Xuping ^a   Wu, Shuming ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; PROTEIN; SCATTER FACTOR;

ADIPOSE DERIVED STEM CELL; ADIPOSE DERIVED STROMAL CELL; ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOVENOUS SHUNT; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; AUTOLOGOUS STROMAL CELL TRANSPLANTATION; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; HEART RIGHT VENTRICLE HYPERTROPHY; HEMODYNAMICS; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INJECTION; INVASIVE PROCEDURE; LUNG; LUNG ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADIPOSE TISSUE; ANIMALS; ARTERIOVENOUS SHUNT, SURGICAL; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL SHAPE; CELL TRANSPLANTATION; CULTURE MEDIA, CONDITIONED; DISEASE MODELS, ANIMAL; FLUORESCENT ANTIBODY TECHNIQUE; HEMODYNAMICS; HEPATOCYTE GROWTH FACTOR; HYPERTENSION, PULMONARY; LUNG; MALE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, WISTAR; STAINING AND LABELING; STROMAL CELLS; TRANSPLANTATION, AUTOLOGOUS;

RATTUS;

EID: 79957859304     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2010.0222     Document Type: Article

References (29)

1. Voelkel NF, RA Quaife, LA Leinwand, RJ Barst, MD McGoon, DR Meldrum, J Dupuis, CS Long, LJ Rubin, FW Smart, YJ Suzuki, M Gladwin, EM Denholm and DB Gail. (2006). Right ventricular function and failure: report of a national heart, lung, and blood institute working group on cellular and molecular mechanisms of right heart failure. Circulation 114:1883-1891. (Pubitemid 44673364)
2. LaRaia AV and AB Waxman. (2007). Pulmonary aterial hypertension: evaluation and management. South Med J 100:393-399. (Pubitemid 46559169)
3. Michelakis ED, MR Wilkins and M Rabinovitch. (2008). Emerging concepts and translational priorities in pulmonary arterial hypertension. Circulation 118:1486-1495.
4. Steele P, G Strange, J Wlodarczyk, B Dalton, S Stewart, E Gabbay and A Keogh. (2010). Hemodynamics in pulmonary arterial hypertension (PAH): do they explain long-term clinical outcomes with PAH-specific therapy. BMC Cardio-vasc Disord 10:9.
5. Ueno T, JA Smith, GI Snell, TJ Williams, TC Kotsimbos, M Rabinov and DS Esmore. (2000). Bilateral sequential single lung transplantation for pulmonary hypertension and Ei-senmenger's syndrome. Ann Thorac Surg 69:381-387. (Pubitemid 30125563)
6. Campbell AI, Y Zhao, R Sandhu and DJ Stewart. (2001). Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension. Circulation 104:2242-2248. (Pubitemid 33043307)
7. Zhao YD, DW Courtman, Y Deng, L Kugathasan, Q Zhang and DJ Stewart. (2005). Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells. Circ Res 96:442-450.
8. Ortiz LA, F Gambelli, C McBride, D Gaupp, M Baddoo, Ni Kaminski and DG Phinney. (2003). Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects. Proc Natl Acad Sci USA 100:8403-8411.
9. Zhu Y, T Liu, K Song, X Fan, X Ma and Z Cui. (2008). Adipose-derived stem cell: a better stem cell than BMSC. Cell Biochem Funct 26:664-675.
10. Bunnell BA, M Flaat, C Gagliardi, B Patel and C Ripoll. (2008). Adipose-derived stem cells: isolation, expansion and differentiation. Methods 45:115-120. (Pubitemid 351885360)
11. DiMuzio P and T Tulenko. (2007). Tissue engineering applications to vascular bypass graft development: the use of adipose-derived stem cells. J Vasc Surg 45(Suppl. A):A99-A103.
12. Rehman J, D Traktuev, J Li, S Merfeld-Clauss, CJ Temm-Grove, JE Bovenkerk, CL Pell, BH Johnstone, RV Considine and KL March. (2004). Secretion of angiogenic and anti-apoptotic factors by human adipose stromal cells. Circulation 109:1292-1298. (Pubitemid 38372789)
13. Nakagami H, K Maeda, R Morishita, S Iguchi, T Nishikawa, Y Takami, Y Kikuchi, Y Saito, K Tamai, T Ogihara and Y Kaneda. (2005). Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vasc Biol 25:2542-2547. (Pubitemid 43732276)
14. Kondo K, S Shintani, R Shibata, H Murakami, R Murakami, M Imaizumi, Y Kitagawa and T Murohara. (2009). Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. Arterioscler Thromb VascBiol 29:61-66.
15. Ono M, Y Sawa, S Mizuno, N Fukushima, H Ichikawa, K Bessho, T Nakamura and H Matsuda. (2004). Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats. Circulation 110:2896-2902. (Pubitemid 39473615)
16. Shigemura N, M Okumura, S Mizuno, Y Imanishi, T Nakamura and Y Sawa. (2006). Autologous transplantation of adipose tissue-derived stromal cells ameliorates pulmonary emphysema. Am J Transplant 6:2592-2600. (Pubitemid 44571679)
17. Uruno A, A Sugawara, H Kanatsuka, S Arima, Y Taniyama, M Kudo, K Takeuchi and S Ito. (2004). Hepatocyte growth factor stimulates nitric oxide production through endothelial nitric oxide synthase activation by the phosphoinositide 3-Kinase=Akt pathway and possibly by mitogen-activated protein kinase kinase in vascular endothelial cells. Hy-pertens Res 27:887-895. (Pubitemid 40309455)
18. Giaid A and D Saleh. (1995). Reduced expression of endo-thelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N Engl J Med 333:214-221.
19. Cuifen Z, W Lijuan, G Li, X Wei, W Zhiyu and L Fuhai. (2008). Changes and distributions of peptides derived from proadrenomedullin in left-to-right shunt pulmonary hypertension of rats. Circ J 72:476-481. (Pubitemid 351600646)
20. Hattori H, Y Nogami, T Tanaka, Y Amano, K Fukuda, S Kishimoto, Y Kanatani, S Nakamura, B Takase and M Ishihara. (2008). Expansion and characterization of adipose tissue-derived stromal cells cultured with low serum medium. J Biomed Mater Res B Appl Biomater 87:229-236.
21. Amos PJ, H Shang, AM Bailey, A Taylor, AJ Katz and SM Peirce. (2008). IFATS collections: the role of human adipose-derived stromal cells in inflammatory microvascular remodeling and evidence of a perivascular phenotype. Stem Cells 26:2682-2690.
22. Weber A, I Pedrosa, A Kawamoto, N Himes, J Munasinghe, T Asahara, NM Rofsky and DW Losordo. (2004). Magnetic resonance mapping of transplanted endothelial progenitor cells for therapeutic neovascularization in ischemic heart disease. Eur J Cardiothorac Surg 26:137-143. (Pubitemid 38759937)
23. Mothe AJ and CH Tator. (2005). Proliferation, migration and differentiation of endogenous ependymal region stem=progenitor cells following minimal spinal cord injury in the adult rat. Neuroscience 131:177-187. (Pubitemid 40170498)
24. McMurtry MS, S Bonnet, X Wu, JR Dyck, A Haromy, K Hashimoto and ED Michelakis. (2004). Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ Res 95:830-840. (Pubitemid 39390586)
25. Mitchell JB, K Mcintosh, S Zvonic, S Garrett, ZE Floyd, A Kloster, Y Dihalvorsen, RW Storms, B Goh, G Kilroy, X Wu and JM Gimble. (2006). Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers. Stem Cells 24:376-385. (Pubitemid 44464807)
26. Planat-Benard V, JS Silvestre, B Cousin, M André, M Nib-belink, R Tamarat, M Clergue, C Manneville, C Saillan-Barreau, M Duriez, A Tedgui, B Levy, L Pénicaud and L Casteilla. (2004). Plasticity of human adipose lineage cells toward endothelial cells physiological and therapeutic perspectives. Circulation 109:656-663. (Pubitemid 38198874)
27. Vilalta M, IR Dégano, J Bagó, D Gould, M Santos, M Garćia-Arranz, R Ayats, C Fuster, Y Chernajovsky, D García-Olmo, N Rubio and J Blanco. (2008). Biodistribution, long-term survival, and safety of human adipose tissue-derived mes-enchymal stem cells transplanted in nude mice by high sensitivity non-invasive bioluminescence imaging. Stem Cells Dev 17:993-1004.
28. Van Belle E, B Witzenbichler, D Chen, M Silver, L Chang R Schwall and JM Isner. (1998). Potentiated angiogenic effect of scatter factor=hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis. Circulation 97:381-390. (Pubitemid 28074339)
29. Ono M, Y Sawa, K Matsumoto, T Nakamura, Y Kaneda and H Matsuda. (2002). In vivo gene transfection with hepato-cyte growth gactor via the pulmonary artery induces an-giogenesis in the rat lung. Circulation 106:I-264-I-269