Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats

Circulation

Volumn 110, Issue 18, 2004, Pages 2896-2902

  Ono, Masamichi ^a   Sawa, Yoshiki ^a,b   Mizuno, Shinya ^a   Fukushima, Norihida ^a   Ichikawa, Hajime ^a   Bessho, Kazuhiko ^a   Nakamura, Toshikazu ^a   Matsuda, Hikaru ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Gene therapy; Growth factor; Pulmonary vasculature; Remodeling

Indexed keywords

COLLAGEN; ENDOTHELIN 1; MESSENGER RNA; MONOCROTALINE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; VIRUS VECTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTERY MUSCLE; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE THERAPY; GENETIC TRANSFECTION; HYPERPLASIA; LUNG ARTERY; LUNG BLOOD VESSEL; LUNG VASCULAR RESISTANCE; MALE; NICK END LABELING; NONHUMAN; PARAINFLUENZA VIRUS 1; PRIORITY JOURNAL; PROTO ONCOGENE; PULMONARY HYPERTENSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUNICA MEDIA;

ANIMALS; ARTERIOLES; COLLAGEN; ENDOTHELIN-1; EXTRACELLULAR MATRIX; FIBROSIS; GENE THERAPY; HEPATOCYTE GROWTH FACTOR; HUMANS; HYPERPLASIA; HYPERTENSION, PULMONARY; MALE; MONOCROTALINE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTO-ONCOGENE PROTEINS C-MET; RATS; RATS, WISTAR; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TUNICA MEDIA;

EID: 8144221953     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000146342.30470.30     Document Type: Article

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