The influence of manipulations to alter ambient GABA concentrations on the hypnotic and immobilizing actions produced by sevoflurane, propofol, and midazolam

Neuropharmacology

Volumn 61, Issue 1-2, 2011, Pages 172-180

  Nishikawa, Koichi ^a   Kubo, Kazuhiro ^a   Obata, Hideaki ^a   Yanagawa, Yuchio ^a   Saito, Shigeru ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

GABA transporter; GABAergic inhibition; GAD65 knockout mice; General anesthetic; Hypnosis; Immobilization

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE 65; MIDAZOLAM; PROPOFOL; SEVOFLURANE;

4 AMINOBUTYRIC ACID BRAIN LEVEL; 4 AMINOBUTYRIC ACID UPTAKE; ANESTHESIOLOGICAL TECHNIQUES; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DRUG POTENTIATION; DRUG RESPONSE; FRONTAL CORTEX; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; GAD65 GENE; GENE DELETION; GENE FUNCTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPNOSIS; IMMOBILIZATION; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RIGHTING REFLEX; SYNAPTIC TRANSMISSION; WITHDRAWAL REFLEX;

ANIMALS; BRAIN; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; HYPNOTICS AND SEDATIVES; IMMOBILITY RESPONSE, TONIC; MALE; METHYL ETHERS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDAZOLAM; PROPOFOL; REFLEX, RIGHTING; SPINAL CORD;

EID: 79957853133     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.03.025     Document Type: Article

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