The p150 subunit of the histone chaperone Caf-1 interacts with the transcriptional repressor Gfi1

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1809, Issue 4-6, 2011, Pages 255-261

  Heyd, Florian ^a   Chen, Riyan ^a   Afshar, Khashayar ^a   Saba, Ingrid ^a,c   Lazure, Claude ^a   Fiolka, Katharina ^b   Möröy, Tarik ^a,b,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Gfi1; P150 subunit of Caf 1; Transcriptional repression

Indexed keywords

CHROMATIN ASSEMBLY FACTOR 1; CHROMATIN ASSEMBLY FACTOR 1 P150 SUBUNIT; GFI PROTEIN; HISTONE DEACETYLASE 1; HISTONE H3; HISTONE H4; LSD 1 PROTEIN; PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; DNA BINDING; GEL PERMEATION CHROMATOGRAPHY; GENE REPRESSION; GENE SILENCING; GENE TARGETING; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HISTONE MODIFICATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; T LYMPHOCYTE;

ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHROMATIN ASSEMBLY FACTOR-1; COS CELLS; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; HL-60 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; MICE, KNOCKOUT; NIH 3T3 CELLS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA INTERFERENCE; THYMUS GLAND; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ZINC FINGERS;

MURINAE;

EID: 79957757009     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2011.04.009     Document Type: Article

References (31)

1. Moroy T. The zinc finger transcription factor growth factor independence 1 (Gfi1). Int J Biochem Cell Biol 2005, 37:541-546.
2. Hock H., Orkin S.H. Zinc-finger transcription factor Gfi-1: versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells. Curr Opin Hematol 2006, 13:1-6.
3. van der Meer L.T., Jansen J.H., van der Reijden B.A. Gfi1 and Gfi1b: key regulators of hematopoiesis. Leukemia 2010, 11:1834-1843.
4. Yucel R., Karsunky H., Klein-Hitpass L., Moroy T. The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+T cell progenitors and CD4/CD8 lineage decision in the thymus. J Exp Med 2003, 197:831-844.
5. Yucel R., Kosan C., Heyd F., Moroy T. Gfi1:green fluorescent protein knock-in mutant reveals differential expression and autoregulation of the growth factor independence 1 (Gfi1) gene during lymphocyte development. J Biol Chem 2004, 279:40906-40917.
6. Hock H., Hamblen M.J., Rooke H.M., Traver D., Bronson R.T., Cameron S., Orkin S.H. Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity 2003, 18:109-120.
7. Rathinam C., Geffers R., Yucel R., Buer J., Welte K., Moroy T., Klein C. The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function. Immunity 2005, 22:717-728.
8. Heyd F., ten Dam G., Moroy T. Auxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicing. Nat Immunol 2006, 7:859-867.
9. Pargmann D., Yucel R., Kosan C., Saba I., Klein-Hitpass L., Schimmer S., Heyd F., Dittmer U., Moroy T. Differential impact of the transcriptional repressor Gfi1 on mature CD4+ and CD8+ T lymphocyte function. Eur J Immunol 2007, 37:3551-3563.
10. Hock H., Hamblen M.J., Rooke H.M., Schindler J.W., Saleque S., Fujiwara Y., Orkin S.H. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature 2004, 431:1002-1007.
11. Zeng H., Yucel R., Kosan C., Klein-Hitpass L., Moroy T. Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J 2004, 23:4116-4125.
12. Duan Z., Zarebski A., Montoya-Durango D., Grimes H.L., Horwitz M. Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. Mol Cell Biol 2005, 25:10338-10351.
13. Duan Z., Person R.E., Lee H.H., Huang S., Donadieu J., Badolato R., Grimes H.L., Papayannopoulou T., Horwitz M.S. Epigenetic regulation of protein-coding and microRNA genes by the Gfi1-interacting tumor suppressor PRDM5. Mol Cell Biol 2007, 27:6889-6902.
14. Vassen L., Fiolka K., Moroy T. Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin. EMBO J 2006, 25:2409-2419.
15. Gaillard P.H., Martini E.M., Kaufman P.D., Stillman B., Moustacchi E., Almouzni G. Chromatin assembly coupled to DNA repair: a new role for chromatin assembly factor I. Cell 1996, 86:887-896.
16. Murzina N., Verreault A., Laue E., Stillman B. Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins. Mol Cell 1999, 4:529-540.
17. Reese B.E., Bachman K.E., Baylin S.B., Rountree M.R. The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. Mol Cell Biol 2003, 23:3226-3236.
18. Hoek M., Stillman B. Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo. Proc Natl Acad Sci U S A 2003, 100:12183-12188.
19. Nabatiyan A., Krude T. Silencing of chromatin assembly factor 1 in human cells leads to cell death and loss of chromatin assembly during DNA synthesis. Mol Cell Biol 2004, 24:2853-2862.
20. Quivy J.P., Grandi P., Almouzni G. Dimerization of the largest subunit of chromatin assembly factor 1: importance in vitro and during Xenopus early development. EMBO J 2001, 20:2015-2027.
21. Houlard M., Berlivet S., Probst A.V., Quivy J.P., Hery P., Almouzni G., Gerard M. CAF-1 is essential for heterochromatin organization in pluripotent embryonic cells. PLoS Genet 2006, 2:e181.
22. Enomoto S., Berman J. Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci. Genes Dev 1998, 12:219-232.
23. Tchenio T., Casella J.F., Heidmann T. A truncated form of the human CAF-1 p150 subunit impairs the maintenance of transcriptional gene silencing in mammalian cells. Mol Cell Biol 2001, 21:1953-1961.
24. Quivy J.P., Gerard A., Cook A.J., Roche D., Almouzni G. The HP1-p150/CAF-1 interaction is required for pericentric heterochromatin replication and S-phase progression in mouse cells. Nat Struct Mol Biol 2008, 15:972-979.
25. Song Y., He F., Xie G., Guo X., Xu Y., Chen Y., Liang X., Stagljar I., Egli D., Ma J., Jiao R. CAF-1 is essential for Drosophila development and involved in the maintenance of epigenetic memory. Dev Biol 2007, 311:213-222.
26. Huang H., Yu Z., Zhang S., Liang X., Chen J., Li C., Ma J., Jiao R. Drosophila CAF-1 regulates HP1-mediated epigenetic silencing and pericentric heterochromatin stability. J Cell Sci 2010, 123:2853-2861.
27. Schonrock N., Exner V., Probst A., Gruissem W., Hennig L. Functional genomic analysis of CAF-1 mutants in Arabidopsis thaliana. J Biol Chem 2006, 281:9560-9568.
28. McGhee L., Bryan J., Elliott L., Grimes H.L., Kazanjian A., Davis J.N., Meyers S. Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism. J Cell Biochem 2003, 89:1005-1018.
29. Rodel B., Tavassoli K., Karsunky H., Schmidt T., Bachmann M., Schaper F., Heinrich P., Shuai K., Elsasser H.P., Moroy T. The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3. EMBO J 2000, 19:5845-5855.
30. Doan L.L., Porter S.D., Duan Z., Flubacher M.M., Montoya D., Tsichlis P.N., Horwitz M., Gilks C.B., Grimes H.L. Targeted transcriptional repression of Gfi1 by GFI1 and GFI1B in lymphoid cells. Nucleic Acids Res 2004, 32:2508-2519.
31. Montoya-Durango D.E., Velu C.S., Kazanjian A., Rojas M.E., Jay C.M., Longmore G.D., Grimes H.L. Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. J Biol Chem 2008, 283:32056-32065.