Expression of myeloid differentiation primary response protein 88 (Myd88) in the cerebral cortex after experimental traumatic brain injury in rats

Brain Research

Volumn 1396, Issue , 2011, Pages 96-104

  Li, Guang Zhao ^a   Zhang, Yang ^b   Zhao, Jin Bing ^b   Wu, Guo Jian ^b   Su, Xing Fen ^b   Hang, Chun Hua ^a,b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

ICAM 1; Inflammatory cytokine; Myeloid differentiation primary; NF B; response protein 88; Traumatic brain injury

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CONTROLLED STUDY; CYTOKINE RELEASE; DNA BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRAUMATIC BRAIN INJURY; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; CYTOKINES; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; MALE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

RATTUS;

EID: 79957670146     PISSN: 00068993     EISSN: 00068993     Source Type: Journal    
DOI: 10.1016/j.brainres.2011.04.014     Document Type: Article

References (44)

1. Babcock, A.A., Toft-Hansen, H., Owens, T., 2008. Signaling through MyD88 regulates leukocyte recruitment after brain injury. J. Immunol. 181, 6481-6490.
2. Barton, G.M., Medzhitov, R., 2003. Toll-like receptor signaling pathways. Science 300, 1524-1525. (Pubitemid 36682871)
3. Burns, K., Martinon, F., Esslinger, C., Pahl, H., Schneider, P., Bodmer, J.L., Di Marco, F., French, L., Tschopp, J., 1998. MyD88, an adapter protein involved in interleukin-1 signaling. J. Biol. Chem. 273, 12203-12209.
4. Chen, G., Shi, J., Ding, Y., Yin, H., Hang, C., 2007. Progesterone prevents traumatic brain injury-induced intestinal nuclear factor kappa B activation and proinflammatory cytokines expression in male rats. Mediators Inflamm. 2007, 93431.
5. Chen, G., Shi, J., Jin, W., Wang, L., Xie, W., Sun, J., Hang, C., 2008. Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion. Ann. Clin. Lab. Sci. 38, 65-74.
6. Chen, G., Zhang, S., Shi, J., Ai, J., Qi, M., Hang, C., 2009. Simvastatin reduces secondary brain injury caused by cortical contusion in rats: possible involvement of TLR4/NF-kappaB pathway. Exp. Neurol. 216, 398-406.
7. Cook, D.N., Pisetsky, D.S., Schwartz, D.A., 2004. Toll-like receptors in the pathogenesis of human disease. Nat. Immunol. 5, 975-979.
8. Davis, C.N., Mann, E., Behrens, M.M., Gaidarova, S., Rebek, M., Rebek, J.J., Bartfai, T., 2006. MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics Proc. Natl Acad. Sci. U. S. A. 103, 2953-2958.
9. Dinarello, C.A., 1999. IL-18: A TH1-inducing, proinflammatory cytokine and new member of the IL-1 family. J. Allergy Clin. Immunol. 103, 11-24.
10. Felderhoff-Mueser, U., Schmidt, O.I., Oberholzer, A., Buhrer, C., Stahel, P.F., 2005. IL-18: a key player in neuroinflammation and neurodegeneration? Trends Neurosci. 28, 487-493.
11. Feng, Y., Zhao, H., Xu, X., Buys, E.S., Raher, M.J., Bopassa, J.C., Thibault, H., Scherrer-Crosbie, M., Schmidt, U., Chao, W., 2008. Innate immune adaptor MyD88 mediates neutrophil recruitment and myocardial injury after ischemia-reperfusion in mice. Am. J. Physiol. Heart Circ. Physiol. 295, H1311-H1318.
12. Gao, Y., Fang, X., Sun, H., Wang, Y., Yao, L.J., Li, J.P., Tong, Y., Zhang, B., Liu, Y., 2009a. Toll-like receptor 4-mediated myeloid differentiation factor 88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in hippocampal CA1 region in mice. Biol. Pharm. Bull. 32, 1665-1671.
13. Gao, Y., Fang, X., Tong, Y., Liu, Y., Zhang, B., 2009b. TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia-reperfusion in cortex in mice. Biomed. Pharmacother. 63, 442-450.
14. Hang, C.H., Shi, J.X., Tian, J., Li, J.S., Wu, W., Yin, H.X., 2004. Effect of systemic LPS injection on cortical NF-kappaB activity and inflammatory response following traumatic brain injury in rats. Brain Res. 1026, 23-32. (Pubitemid 39336413)
15. Hang, C.H., Shi, J.X., Li, J.S., Wu, W., Yin, H.X., 2005. Concomitant upregulation of nuclear factor-kB activity, proinflammatory cytokines and ICAM-1 in the injured brain after cortical contusion trauma in a rat model. Neurol. India 53, 312-317. (Pubitemid 41526843)
16. Hoshino, K., Kaisho, T., Iwabe, T., Takeuchi, O., Akira, S., 2002. Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation. Int. Immunol. 14, 1225-1231.
17. Hua, F., Wang, J., Sayeed, I., Ishrat, T., Atif, F., Stein, D.G., 2009. The TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice. Biochem. Biophys. Res. Commun. 390, 678-683.
18. Kielian, T., 2006. Toll-like receptors in central nervous system glial inflammation and homeostasis. J. Neurosci. Res. 83, 711-730.
19. Kielian, T., Phulwani, N.K., Esen, N., Syed, M.M., Haney, A.C., McCastlain, K., Johnson, J., 2007. MyD88-dependent signals are essential for the host immune response in experimental brain abscess. J. Immunol. 178, 4528-4537. (Pubitemid 46492405)
20. Koedel, U., Merbt, U.M., Schmidt, C., Angele, B., Popp, B., Wagner, H., Pfister, H.W., Kirschning, C.J., 2007. Acute brain injury triggers MyD88-dependent, TLR2/4-independent inflammatory responses. Am. J. Pathol. 171, 200-213.
21. Landreth, G.E., Reed-Geaghan, E.G., 2009. Toll-like receptors in Alzheimer's disease. Curr. Top. Microbiol. Immunol. 336, 137-153.
22. Lehnardt, S., Lehmann, S., Kaul, D., Tschimmel, K., Hoffmann, O., Cho, S., Krueger, C., Nitsch, R., Meisel, A., Weber, J.R., 2007. Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia. J. Neuroimmunol. 190, 28-33. (Pubitemid 47625604)
23. Loiarro, M., Capolunghi, F., Fanto, N., Gallo, G., Campo, S., Arseni, B., Carsetti, R., Carminati, P., De Santis, R., Ruggiero, V., Sette, C., 2007. Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound. J. Leukoc. Biol. 82, 801-810.
24. Ma, C.X., Yin, W.N., Cai, B.W., Wu, J., Wang, J.Y., He, M., Sun, H., Ding, J.L., You, C., 2009. Toll-like receptor 4/nuclear factor-kappa B signaling detectedinbrainafter early subarachnoid hemorrhage. Chin. Med. J. (Engl.) 122, 1575-1581.
25. McKean, D.J., Bell, M., Huntoon, C., Rastogi, S., Van Norstrand, M., Podzorski, R., Nilson, A., Paya, C., 1995. IL-1 receptor and TCR signals synergize to activate NF-kappa B-mediated gene transcription. Int. Immunol. 7, 9-20.
26. Memet, S., 2006. NF-kappaB functions in the nervous system: from development to disease. Biochem. Pharmacol. 72, 1180-1195.
27. Mishra, B.B., Gundra, U.M., Teale, J.M., 2009. Toll-like receptors in CNS parasitic infections. Curr. Top. Microbiol. Immunol. 336, 83-104.
28. Morganti-Kossmann, M.C., Rancan, M., Otto, V.I., Stahel, P.F., Kossmann, T., 2001. Role of cerebral inflammation after traumatic brain injury: a revisited concept. Shock 16, 165-177. (Pubitemid 33598193)
29. Nonaka, M., Chen, X.H., Pierce, J.E., Leoni, M.J., McIntosh, T.K., Wolf, J.A., Smith, D.H., 1999. Prolonged activation of NF-kappaB following traumatic brain injury in rats. J. Neurotrauma 16, 1023-1034.
30. O'Brien, K., Fitzgerald, D.C., Naiken, K., Alugupalli, K.R., Rostami, A.M., Gran, B., 2008. Role of the innate immune system in autoimmune inflammatory demyelination. Curr. Med. Chem. 15, 1105-1115.
31. Prendergast, C.T., Anderton, S.M., 2009. Immune cell entry to central nervous system - current understanding and prospective therapeutic targets. Endocr. Metab. Immune Disord. Drug Targets 9, 315-327.
32. Racke, M.K., Drew, P.D., 2009. Toll-like receptors in multiple sclerosis. Curr. Top. Microbiol. Immunol. 336, 155-168.
33. Schmidt, O.I., Heyde, C.E., Ertel, W., Stahel, P.F., 2005. Closed head injury - an inflammatory disease? Brain Res. Brain Res. Rev. 48, 388-399.
34. Sette, C., 2007. Rational design of MyD88 inhibitors - new pathways to inflammatory control: an interview with Dr. Claudio Sette by Helene F. Rosenberg. J. Leukoc. Biol. 82, 811-812.
35. Sifringer, M., Stefovska, V., Endesfelder, S., Stahel, P.F., Genz, K., Dzietko, M., Ikonomidou, C., Felderhoff-Mueser, U., 2007. Activation of caspase-1 dependent interleukins in developmental brain trauma. Neurobiol. Dis. 25, 614-622.
36. Stevens, S.L., Ciesielski, T.M., Marsh, B.J., Yang, T., Homen, D.S., Boule, J.L., Lessov, N.S., Simon, R.P., Stenzel-Poore, M.P., 2008. Toll-like receptor 9: a new target of ischemic preconditioning in the brain. J. Cereb. Blood Flow Metab. 28, 1040-1047.
37. Tang, S.C., Arumugam, T.V., Xu, X., Cheng, A., Mughal, M.R., Jo, D.G., Lathia, J.D., Siler, D.A., Chigurupati, S., Ouyang, X., Magnus, T., Camandola, S., Mattson, M.P., 2007. Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc. Natl Acad. Sci. U. S. A. 104, 13798-13803.
38. Tehranian, R., Andell-Jonsson, S., Beni, S.M., Yatsiv, I., Shohami, E., Bartfai, T., Lundkvist, J., Iverfeldt, K., 2002. Improved recovery and delayed cytokine induction after closed head injury in mice with central overexpression of the secreted isoform of the interleukin-1 receptor antagonist. J. Neurotrauma 19, 939-951.
39. Teng, W., Wang, L., Xue, W., Guan, C., 2009. Activation of TLR4-mediated NF kappaB signaling in hemorrhagic brain in rats. Mediators Inflamm. 2009, 473276.
40. Verstrepen, L., Bekaert, T., Chau, T.L., Tavernier, J., Chariot, A., Beyaert, R., 2008. TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common theme. Cell. Mol. Life Sci. 65, 2964-2978.
41. Yamamoto, M., Takeda, K., Akira, S., 2004. TIR domain-containing adaptors define the specificity of TLR signaling. Mol. Immunol. 40, 861-868.
42. Yang, C.M., Luo, S.F., Hsieh, H.L., Chi, P.L., Lin, C.C., Wu, C.C., Hsiao, L.D., 2010. Interleukin-1beta induces ICAM-1 expression enhancing leukocyte adhesion in human rheumatoid arthritis synovial fibroblasts: involvement of ERK, JNK, AP-1, and NF-kappaB. J. Cell. Physiol. 224, 516-526.
43. Yatsiv, I., Morganti-Kossmann, M.C., Perez, D., Dinarello, C.A., Novick, D., Rubinstein, M., Otto, V.I., Rancan, M., Kossmann, T., Redaelli, C.A., Trentz, O., Shohami, E., Stahel, P.F., 2002. Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury. J. Cereb. Blood Flow Metab. 22, 971-978.
44. Zaheer, A., Sahu, S.K., Wu, Y., Zaheer, A., Haas, J., Lee, K., Yang, B., 2007. Diminished cytokine and chemokine expression in the central nervous system of GMF-deficient mice with experimental autoimmune encephalomyelitis. Brain Res. 1144, 239-247. (Pubitemid 46440840)