The pharmacological activities of prunes: The dried plums

Journal of Medicinal Plants Research

Volumn 5, Issue 9, 2011, Pages 1508-1511

  Jabeen, Qaiser ^a   Aslam, Naveed ^a  

^a THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

Author keywords

Anticancer; Antihyperlipedimeic; Antihypertensive; Antioxidant; Anxiolytic; Laxative; Osteoporosis; Prunes

Indexed keywords

4 AMINO 4 CARBOXYCHROME 2 ONE; CAFFEIC ACID; CAFFEOYLQUINIC ACID; CHLOROGENIC ACID; COLESTYRAMINE; COUMARIC ACID; COUMARIN DERIVATIVE; FLAVANOID; LIGNIN; NEOCHLOROGENIC ACID; PLANT MEDICINAL PRODUCT; POLYPHENOL; PROTOCATECHUIC ACID; UNCLASSIFIED DRUG;

ANTIHYPERTENSIVE ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANXIETY DISORDER; ATHEROSCLEROSIS; COGNITIVE DEFECT; CONSTIPATION; CYANIDE POISONING; DIET SUPPLEMENTATION; DIETARY FIBER; DRUG EFFECT; DRUG POTENTIATION; FOOD COMPOSITION; FOOD INTAKE; HUMAN; HYPERCHOLESTEROLEMIA; NONHUMAN; NUTRITIONAL VALUE; OSTEOLYSIS; PRUNUS AMERICANA; PRUNUS DOMESTICA; PRUNUS SALICINA; REVIEW; ROSACEAE; TRANQUILIZING ACTIVITY; TREATMENT CONTRAINDICATION;

PRUNUS AMERICANA; PRUNUS DOMESTICA; PRUNUS SALICINA;

EID: 79957668406     PISSN: 19960875     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Review

References (42)

1. Abbasi AM, Khan MA, Ahmad M, Zafar M, Khan H, Muhammad N, Sultana S (2009). Medicinal plants used for the treatment of jaundice and hepaptitis based on socio-economic documentation. Afr. J. Biotechnol., 8: 1643-1650.
2. Ahmed T, Sadia H, Khalid A, Batool S, Janjua A (2010). Report: prunes and liver function: a clinical trial. Pak. J. Pharm. Sci., 23: 463-466.
3. Arjmandi BH (2001). The role of phytoestrogens in the prevention and treatment of osteoporosis in ovarian hormone deficiency. J. Am. College Nutri., 20: 398S-402S.
4. Bouayed J, Rammal H, Dicko A, Younos C, Soulimani R (2007). Chlorogenic acid, a polyphenol from Prunus domestica (Mirabelle), with coupled anxiolytic and antioxidant effects. J. Neurol. Sci., 262: 77-84.
5. Bouayed J, Rammal H, Soulimani R (2009). Oxidative stress and anxiety, relationship and cellular pathways. Oxid. Med. Cell Longev., 2: 63-67.
6. Bu SY, Lerner M, Stoecker BJ, Boldrin E, Brackett DJ, Lucas EA, Smith BJ (2008). Dried plum polyphenols inhibit osteoclastogenesis by downregulating NFATc1 and inflammatory mediators. Calcif. Tissue Int., 82: 475-488.
7. Bu SY, Lucas EA, Franklin M, Marlow D, Brackett DJ, Boldrin EA, Devareddy L, Arjmandi BH, Smith BJ (2007). Comparison of dried plum supplementation and intermittent PTH in restoring bone in osteopenic orchidectomized rats. Osteoporosis Int., 18: 931-942.
8. Cakilcioglu U, Turkoglu I (2009). Plants used to lower blood sugar in Elazig Central District. Acta Hortic. (ISHS), 826: 97-104.
9. Donovan JL, Meyer AS, Waterhouse AL (1998). Phenolic composition and antioxidant activity of prunes and prune juice (Prunus domestica). J. Agric. Food Chem., 46: 1247-1252.
10. Duke JA, Bogenschutz GMJ, Du CJ, Duke PK (2002). Handbook of Medicinal Herbs. CRC Press, USA, p. 577.
11. Ferrel V (1998). Alternative cancer remedies-Facts from histories and medical researches. Pligrims Books, USA, pp. 117-130.
12. Fujii T, Ikami T, Xu J, Ikeda, K (2006). Prune extract (Prunus domestica L.) supresses the proliferantion and induces apoptosis of human colon carcinoma Caco-2. J. Nutr. Sci. Vitaminol., 52: 389-391.
13. Gallaher CM, Gallaher DD (2009). Dried plums (prunes) reduce atherosclerosis lesion area in apolipoprotein E-deficient mice. Br. J. Nutr., 101: 233-239.
14. Halloran BP, Wronski TJ, VonHerzen DC, Chu V, Xia X, Pingel JE, Williams AA, Smith BJ (2010). Dietary Dried Plum Increases Bone Mass in Adult and Aged Male Mice. J. Nutr., 140: 1781-1787.
15. Hooshmand H, Arjmandi BH (2009). Dried plum, an emerging functional food that may effectively improve bone health. Ageing Res. Rev., 8: 122-127.
16. Ismail HM, Williams AA (1981). The flavour of plums (Prunus domestica L.). An examination of the aroma components of plum juice from the cultivar victoria. J. Agric. Food Chem., 32: 613-619.
17. Jhones JS, Bullis DE (1929). The chemical composition and food value of Oregon dried prunes. Agric. Exp. Station Bull., 249: 1-10.
18. Kahlon TS, Smith GE (2007). In vitro binding of bile acids by blueberries (Vaccinium spp.), plums (Prunus spp.), prunes (Prunus spp.), strawberries (Fragaria Xananassa), cherries (Malpighia punicifolia), cranberries (Vaccinium macrocarpon) and apples (Malus sylvestris). Food Chem., 100: 1182-1187.
19. Kayano SI, Kikuzaki H, Fukutsuka N, Mitani T, Nakatani N (2002). Antioxidant activity of prune (Prunus domestica L.) constituents and a new synergist. J. Agric. Food Chem., 50: 3708-3712.
20. Kayano SI, Kikuzaki H, Yamada NF, Aoki A, Kasamatsu K, Yamasaki Y, Ikami T, Suzuki T, Mitani T, Nakatani N (2004). Antioxidant properties of prunes (Prunus domestica L.) and their constituents. BioFactors, 21: 309-313.
21. Kikuzaki H, Kayano S, Fukutsuka N, Aoki A, Kasamatsu K, Yamasaki Y, Mitani T, Nakatani N (2004). Abscisic acid related compounds and lignins in prunes (Prunus domestica L.) and their oxygen radical absorbance capacity (ORAC). J. Agric. Food Chem., 52: 344-349.
22. Kimura Y, Ito H, Kawaji M, Ikami T, Hatano T (2008). Characterization and antioxidative properties of oligomeric proanthocyanidin from prunes, dried fruit of Prunus domestica L. Biosci. Biotechnol. Biochem., 72: 1615-1618.
23. Li TSC (2008). Vegetables and fruits: nutritional and therapeutic values. Taylor and Francis Group, USA, pp. 169, 195, 198, 202-203.
24. Lucas EA, Hammond LJ, Mocanu V, Arquitt AB, Trolinger A, Khalil DA, Smith BJ, Soung DY, Daggy BP, Arjamandi BH (2004). Daily consumption of dried Plum by postmenopausal women does not cause undesirable changes in bowel function. J. Appl. Res., 4: 37-43.
25. Madaru MA, Sanguinetti AM, Caro AD, Fadda C, Piga A (2010). Contribution of melanoidins to the antioxidant activity of prunes. J. Food Qual., 33: 155-170.
26. Nakatani N, Kayano S, Kikuzaki H, Sumino S, Katagiri K, Mitani T (2000). Identification, quantitative determination and antioxidative activities of Chlorogenic acid isomers in Prune (Prunus domestica L.). J. Agric. Food Chem., 48: 5512-5516.
27. Negishi H, Onobayashi Y, Xu JW, Njelekela, MA, Kobayakawa A, Yasui N, Yamamoto J, Ikami T, Ikeda K, Yamori Y (2007). Effects of prune extract on blood pressure elevation in stroke-prone spontaneously hypertensive rats. Clin. Exp. Pharmacol. Physiol., 34: S47-S48.
28. Piirainenad L, Peuhkurib K, Backstromb K, Korpelabcd R, Salminene S (2007). Prune juice has a mild laxative effect in adults with certain gastrointestinal symptoms. Nutr. Res., 27: 511-513.
29. Ritchie J (1972). Mass peristalsis in the human colon after contact with oxyphenisatin. Gut, 13: 211-219.
30. Sabarez HT, Price WE, Korth J (2000). Volatile changes during dehydration of d'Agen prunes. J. Agric. Food Chem., 48: 1838-1842.
31. Sairanen U, Piirainen L, Nevala R, Korpela R (2007). Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. Eur. J. Clin. Nutr., 61: 1423-1428.
32. Shukitt HB, Kalt W, Carey AN, Vinqvist-Tymchuk M, McDonald J, Joseph JA (2009). Plum juice, but not dried plum powder, is effective in mitigating cognitive deficits in aged rats. Nutrition, 25: 567-573.
33. Siddiq M (2006). Plums and Prunes. In Hui, YH (ed) Handbook of Fruits and Fruit Processing. Blackwell Publishing Professional, Lowa, pp. 553-564.
34. Smith BJ (2007). Dried plum improves bone density and microarchitecture by up-regulating osteoblast activity and downregulating osteoclast differentiation. Acta Hort. (ISHS). 841: 441-448.
35. Stacewicz SM, Bowen PE, Hussain EA, Damayanti WBI, Farnsworth NR (2001). Chemical composition and potential health effects of prunes: a functional food. Crit. Rev. Food. Sci. Nutr., 41: 251-286.
36. Tanaka T, Tanaka T, Tanaka M (2011). Potential cancer chemopreventive activity of protocatechuic acid. J. Exp. Clin. Med., Article in press.
37. Tinker LF, Davis PA, Schneeman BO (1994). Prune fiber or pectin compared with cellulose lowers plasma and liver lipids in rats with diet-induced hyperlipidemia. J. Nutr., 124: 31-40.
38. Tinker LF, Schneeman BO, Davis PA, Gallaher DD, Waggoner CR (1991). Consumption of prunes as a source of dietary fiber in men with mild hypercholesterolemia. Am. J. Clin. Nutr., 53: 1259-1265.
39. Usmanghani K, Honda G, Miki W (1986). Herbal drugs and herbalists in Pakistan. Institute for the study of languages and cultures of Asia and Africa, Japan, p. 48.
40. Usmanghani K, Saeed A, Alam MT (1997). Indusyunic Medicine. Department of Pharmacognosy, Faculity of Pharmacy, University of Karachi, Pakistan, pp. 363-364.
41. Vetter J (2000). Plant cyanogenic glycosides. Toxicon., 38: 11-36.
42. Wu X, Beecher GR, Holden JM, Haytowitz GB, Gebhardt SE, Prior RL (2004). Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J. Agric. Food Chem., 52: 4026-4037.