Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons

Molecular Neurodegeneration

Volumn 6, Issue 1, 2011, Pages

  Liang, Qiuli ^a,b   Ouyang, Xiaosen ^a,b   Schneider, Lonnie ^a,b   Zhang, Jianhua ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

autophagy; cathepsin; huntingtin; lysosome

Indexed keywords

CATHEPSIN B; CATHEPSIN D; HUNTINGTIN; MUTANT PROTEIN; PROTEINASE;

ARTICLE; AUTOPHAGY; BIOACCUMULATION; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LYSOSOME; MOLECULAR BIOLOGY; NERVE CELL; NEUROPROTECTION; PROTEIN EXPRESSION; TOXICITY;

EID: 79957643515     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-6-37     Document Type: Article

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