-
1
-
-
0027966932
-
Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men
-
Chan JM, Stampfer MJ, Ribb EB et al. Obesity, fat distribution and weight gain as risk factors for clinical diabetes in man. Diabetes Care 1994 ; 17: 961-9. (Pubitemid 24268605)
-
(1994)
Diabetes Care
, vol.17
, Issue.9
, pp. 961-969
-
-
Chan, J.M.1
Rimm, E.B.2
Colditz, G.A.3
Stampfer, M.J.4
Willett, W.C.5
-
3
-
-
0035856017
-
Diet, lifestyle, and the risk of type 2 diabetes mellitus in women
-
Hu FB, Manson JE, Stampfer MJ et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med 2001 ; 345: 730-37.
-
(2001)
N Engl J Med
, vol.345
, pp. 730-37
-
-
Hu, F.B.1
Manson, J.E.2
Stampfer, M.J.3
-
4
-
-
0032742418
-
The disease burden associated with overweight and obesity
-
Must A., Spandano J., Coakley EH et al. The disease burden associated with overweight and obesity. JAMA 1999 ; 282: 153-9.
-
(1999)
JAMA
, vol.282
, pp. 153-9
-
-
Must, A.1
Spandano, J.2
Coakley, E.H.3
-
5
-
-
0037223174
-
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
-
Mokdad AH, Ford ES, Bowman BA et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 2003 ; 289: 76-9.
-
(2003)
JAMA
, vol.289
, pp. 76-9
-
-
Mokdad, A.H.1
Ford, E.S.2
Bowman, B.A.3
-
6
-
-
43549095735
-
Relation of central adiposity and body mass index to the development of diabetes in the Diabetes Prevention Program
-
Bray GA, Jablonski KA, Fujimoto WY et al. Relation of central adiposity and body mass index to the development of diabetes in the Diabetes Prevention Program. Am J Clin Nutr 2008 ; 87: 1212-8. (Pubitemid 351679760)
-
(2008)
American Journal of Clinical Nutrition
, vol.87
, Issue.5
, pp. 1212-1218
-
-
Bray, G.A.1
Jablonski, K.A.2
Fujimoto, W.Y.3
Barrett-Connor, E.4
Haffner, S.5
Hanson, R.L.6
Hill, J.O.7
Hubbard, V.8
Kriska, A.9
Stamm, E.10
Pi-Sunyer, F.X.11
-
7
-
-
33748512353
-
Type 2 diabetes and cardiovascular risk in the UK south Asian community
-
DOI 10.1007/s00125-006-0325-1
-
Barnett AH, Dixon AN, Bellary S. et al. Type 2 diabetes and cardiovascular risk in the UK South Asian community. Diabetologia 2006 ; 49: 2234-46. (Pubitemid 44359083)
-
(2006)
Diabetologia
, vol.49
, Issue.10
, pp. 2234-2246
-
-
Barnett, A.H.1
Dixon, A.N.2
Bellary, S.3
Hanif, M.W.4
O'Hare, J.P.5
Raymond, N.T.6
Kumar, S.7
-
8
-
-
0346687665
-
The Y-Y paradox
-
DOI 10.1016/S0140-6736(03)15269-5
-
Yajnik CS, Yudkin JS The Y-Y paradox. Lancet 2004 ; 363: 163. (Pubitemid 38068336)
-
(2004)
Lancet
, vol.363
, Issue.9403
, pp. 163
-
-
Yajnik, C.S.1
Yudkin, J.S.2
-
9
-
-
85066456886
-
Appropriate body mass index for Asian populations and its implications for policy and intervention strategies
-
WHO expert consultation. Appropriate body mass index for Asian populations and its implications for policy and intervention strategies. Lancet 2004 ; 363: 157-63.
-
(2004)
Lancet
, vol.363
, pp. 157-63
-
-
-
10
-
-
79953163759
-
Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: Collaborative analysis of 58 prospective studies
-
The Emerging Risk Factor Collaboration
-
The Emerging Risk Factor Collaboration. Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet 2011 ; 377: 1085-95.
-
(2011)
Lancet
, vol.377
, pp. 1085-95
-
-
-
11
-
-
0034119138
-
The perils of portliness: Causes and consequences of visceral adiposity
-
Montague CT, O'Rahilly S. The perils of portliness: causes and consequences of visceral adiposity. Diabetes 2000 ; 49: 883-8. (Pubitemid 30349408)
-
(2000)
Diabetes
, vol.49
, Issue.6
, pp. 883-888
-
-
Montague, C.T.1
O'Rahilly, S.2
-
12
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G., Walters GB, Gudbjartsson DF et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009 ; 41: 18-24.
-
(2009)
Nat Genet
, vol.41
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
-
13
-
-
70450193472
-
Human genetics illuminates the paths to metabolic disease
-
O'Rahilly S. Human genetics illuminates the paths to metabolic disease. Nature 2009 ; 402: 307-14.
-
(2009)
Nature
, vol.402
, pp. 307-14
-
-
O'Rahilly, S.1
-
14
-
-
0036092239
-
Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
-
McGarry JD Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002 ; 51: 7-18.
-
(2002)
Diabetes
, vol.51
, pp. 7-18
-
-
McGarry, J.D.1
-
15
-
-
85056073357
-
Obesity, insulin resistance, type 2 diabetes and free fatty acids
-
Boden G. Obesity, insulin resistance, type 2 diabetes and free fatty acids. Exp Rev Enocrinol Metab 2006 ; 1: 499-505.
-
(2006)
Exp Rev Enocrinol Metab
, vol.1
, pp. 499-505
-
-
Boden, G.1
-
16
-
-
0024392514
-
Glucose and FFA metabolism in non-insulin dependent diabetes mellitus. Evidence for multiple sites of insulin resistance
-
Groop LC, Bonadonna RC, Del Prato S. et al. Glucose and FFA metabolism in non-insulin dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J Clin Invest 1989 ; 84: 205-15.
-
(1989)
J Clin Invest
, vol.84
, pp. 205-15
-
-
Groop, L.C.1
Bonadonna, R.C.2
Del Prato, S.3
-
17
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI Cellular mechanisms of insulin resistance. J Clin Invest 2000 ; 106: 171-6. (Pubitemid 30483118)
-
(2000)
Journal of Clinical Investigation
, vol.106
, Issue.2
, pp. 171-176
-
-
Shulman, G.I.1
-
19
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
DOI 10.1038/414799a
-
Saltiel AR, Kahn CR Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001 ; 414: 799-806. (Pubitemid 34000783)
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
20
-
-
0024026298
-
The triumvirate: Beta cell, muscle, liver. A collusion responsible for NIDDM
-
DeFronzo RA The triumvirate: beta cell, muscle, liver. A collusion responsible for NIDDM. Diabetes 1988 ; 37: 667-87.
-
(1988)
Diabetes
, vol.37
, pp. 667-87
-
-
Defronzo, R.A.1
-
21
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
DOI 10.1038/nature05482, PII NATURE05482
-
Kahn SE, Hull RL, Utzschneider KM Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006 ; 444: 840-6. (Pubitemid 46024990)
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
22
-
-
46049089412
-
Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in type 2 diabetes
-
Kotronen A., Juurinen L., Tiikkainen M. et al. Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in type 2 diabetes. Gastroenterology 2008 ; 135: 122-390.
-
(2008)
Gastroenterology
, vol.135
, pp. 122-390
-
-
Kotronen, A.1
Juurinen, L.2
Tiikkainen, M.3
-
23
-
-
0036381998
-
Adipose tissue as a buffer for daily lipid flux
-
Frayn KN Adipose tissue as a buffer for daily lipid flux. Diabetologia 2002 ; 45: 1201-10.
-
(2002)
Diabetologia
, vol.45
, pp. 1201-10
-
-
Frayn, K.N.1
-
26
-
-
33745095399
-
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
-
DOI 10.1056/NEJMoa054862
-
Graham TE, Yang Q., Bluher M. et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med 2006 ; 354: 2552-63. (Pubitemid 43882351)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.24
, pp. 2552-2563
-
-
Graham, T.E.1
Yang, Q.2
Bluher, M.3
Hammarstedt, A.4
Ciaraldi, T.P.5
Henry, R.R.6
Wason, C.J.7
Oberbach, A.8
Jansson, P.-A.9
Smith, U.10
Kahn, B.B.11
-
27
-
-
3843068833
-
Resistin/ADSF/FIZZ3 in obesity and diabetes
-
Sul HS Resistin/ADSF/FIZZ3 in obesity and diabetes. Trends Endocrinol Metab 2004 ; 15: 247-9.
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 247-9
-
-
Sul, H.S.1
-
28
-
-
18844432308
-
Adiponectin and adiponectin receptors
-
DOI 10.1210/er.2005-0005
-
Kadowaki T., Yamauchi T. Adiponectin and adiponectin receptors. Endocr Revs 2005 ; 26: 439-51. (Pubitemid 40686653)
-
(2005)
Endocrine Reviews
, vol.26
, Issue.3
, pp. 439-451
-
-
Kadowaki, T.1
Yamauchi, T.2
-
29
-
-
4043077286
-
11β-Hydroxysteroid dehydrogenase type 1: A tissue-specific regulator of glucocorticoid response
-
DOI 10.1210/er.2003-0031
-
Tomlinson JW, Walker EA, Bujalska IJ et al. 11 beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Revs 2004 ; 25: 831-66. (Pubitemid 39366049)
-
(2004)
Endocrine Reviews
, vol.25
, Issue.5
, pp. 831-866
-
-
Tomlinson, J.W.1
Walker, E.A.2
Bujalska, I.J.3
Draper, N.4
Lavery, G.G.5
Cooper, M.S.6
Hewison, M.7
Stewart, P.M.8
-
30
-
-
0037283601
-
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
-
Kahn SE The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003 ; 46: 3-19. (Pubitemid 36237741)
-
(2003)
Diabetologia
, vol.46
, Issue.1
, pp. 3-19
-
-
Kahn, S.E.1
-
31
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
DOI 10.2337/diabetes.52.1.102
-
Butler A., Janson J., Bonner-Weir S., Butler P. B-cell deficit and increased b-cell apoptosis in humans with type 2 diabetes. Diabetes 2003 ; 52: 102-10. (Pubitemid 36042113)
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
32
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R., Rocheleau G., Rung J. et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007 ; 445: 881-5.
-
(2007)
Nature
, vol.445
, pp. 881-5
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
-
33
-
-
0035125917
-
Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover
-
Unger RH, Zhou YT Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover. Diabetes 2001 ; 50 (suppl 1). S118-21.
-
(2001)
Diabetes
, vol.50
, Issue.1
, pp. 118-21
-
-
Unger, R.H.1
Zhou, Y.T.2
-
34
-
-
2642653233
-
Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice
-
Kulkarni RN, Wang ZI, Wang EM et al. Leptin rapidly suppresses insulin release from insulinoma cells rat and human islets and in vivo in mice. J Clin Invest 1997 ; 100: 2729-36. (Pubitemid 28007540)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.11
, pp. 2729-2736
-
-
Kulkarni, R.N.1
Wang, Z.-L.2
Wang, R.-M.3
Hurley, J.D.4
Smith, D.M.5
Ghatei, M.A.6
Withers, D.J.7
Gardiner, J.V.8
Bailey, C.J.9
Bloom, S.R.10
-
35
-
-
57749094069
-
Glucose sensing and the pathogenesis of obesity and type 2 diabetes
-
Thorens B. Glucose sensing and the pathogenesis of obesity and type 2 diabetes. Int J Obes 2008 ; 32 (Suppl6). S62-71.
-
(2008)
Int J Obes
, vol.32
, Issue.SUPPL. 6
, pp. 62-71
-
-
Thorens, B.1
|