The Plasmodium falciparum Ca2+-ATPase PfATP6: Insensitive to artemisinin, but a potential drug target

Biochemical Society Transactions

Volumn 39, Issue 3, 2011, Pages 823-831

  Arnou, Bertrand ^a,b   Montigny, Cédric ^c   Morth, Jens Preben ^a,b,d   Nissen, Poul ^a,b   Jaxel, Christine ^c   Møller, Jesper V ^a,b   Le Maire, Marc ^c  

^a DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^b Department of Physiology and Biophysics ^*  (Denmark)

^c CNRS   (France)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

Artemisinin; Ca2+ ATPase; Malaria; P type ATPase; Plasmodium falciparum Ca 2+ ATPase (PfATP6); Sarcoplasmic endoplasmic reticulum Ca2+ ATPase (SERCA)

Indexed keywords

2,5 DI (TERT BUTYL) 1,4 HYDROQUINONE; ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE (CALCIUM) PFATP6; ADENOSINE TRIPHOSPHATE; ARTEMISININ; ARTEMISININ DERIVATIVE; ARTEMISONE; ARTESUNATE; CALCIUM ION; CYCLOPIAZONIC ACID; DIHYDROARTEMISININ; HYDROQUINONE DERIVATIVE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 1A; THAPSIGARGIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANTIMALARIAL ACTIVITY; BINDING AFFINITY; CALCIUM HOMEOSTASIS; CONFERENCE PAPER; DRUG BINDING; DRUG INHIBITION; DRUG PROTEIN BINDING; DRUG SENSITIVITY; DRUG TARGETING; ENZYME ACTIVITY; HETEROLOGOUS EXPRESSION; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN HYDROLYSIS; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; SARCOPLASMIC RETICULUM; YEAST;

ANIMALS; ANTI-INFECTIVE AGENTS; ARTEMISININS; BINDING SITES; CALCIUM-TRANSPORTING ATPASES; DRUG DESIGN; HUMANS; ISOENZYMES; MALARIA; MODELS, MOLECULAR; PLASMODIUM FALCIPARUM; PROTEIN CONFORMATION; RABBITS;

EUKARYOTA; ORYCTOLAGUS CUNICULUS; PLASMODIUM FALCIPARUM;

EID: 79957475440     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0390823     Document Type: Conference Paper

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