Impairment of the activity of the plasma membrane Ca2+-ATPase in Alzheimer's disease

Biochemical Society Transactions

Volumn 39, Issue 3, 2011, Pages 819-822

  Mata, Ana M ^a   Berrocal, María ^a   Sepúlveda, M Rosario ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

Author keywords

Aging; Alzheimer's disease; Cholesterol; Lipid raft; Neurodegeneration; Plasma membrane Ca2+ ATPase (PMCA)

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMYLOID BETA PROTEIN; CALCIUM ION; CHOLESTEROL; GANGLIOSIDE; LIPID; PLASMA MEMBRANE CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; PLASMA MEMBRANE CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 4; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SECRETORY PATHWAY CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG;

AGING; ALZHEIMER DISEASE; AMYLOID PLAQUE; BRAIN; BRAIN DYSFUNCTION; CALCIUM HOMEOSTASIS; CEREBELLUM; CONFERENCE PAPER; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME INHIBITION; HISTOPATHOLOGY; HUMAN; LIPID RAFT; NERVE CELL; NERVE CELL INHIBITION; NERVE CELL PLASTICITY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SWINE; SYNAPTOSOME;

ALZHEIMER DISEASE; ANIMALS; BRAIN; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CELL MEMBRANE; CHOLESTEROL; HUMANS; ISOENZYMES; MEMBRANE MICRODOMAINS; PLAQUE, AMYLOID;

SUIDAE;

EID: 79957457516     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0390819     Document Type: Conference Paper

References (32)

1. 2+ homeostasis. Prog. Neurobiol. 37, 255-285
2. Ghosh, A. and Greenberg, M.E. (1995) Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science 268, 239-247
3. Khachaturian, Z.S. (1994) Calcium hypothesis of Alzheimer's disease and brain aging. Ann. N.Y. Acad. Sci. 747, 1-11
4. Berridge, M.J. (2010) Calcium hypothesis of Alzheimer's disease. Pflügers Arch. 459, 441-449
5. Bezprozvanny, I. and Mattson, M.P. (2008) Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci. 31, 454-463
6. Arispe, N., Rojas, E. and Pollard, H.B. (1993) Alzheimer disease amyloid β protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. Proc. Natl. Acad. Sci. U.S.A. 90, 567-571
7. Duchen, M.R. (2000) Mitochondria and calcium: from cell signalling to cell death. J. Physiol. 529, 57-68
8. +-ATPase activity in hippocampal neurons. Brain Res. 756, 205-214
9. Brini, M. and Carafoli, E. (2009) Calcium pumps in health and disease. Physiol. Rev. 89, 1341-1378
10. 2+-dependent ATPase in rat brain synaptosomes, synaptic membranes, and microsomes. J. Biol. Chem. 258, 6101-6168
11. 2+ ATPase in the rat brain. J. Comp. Neurol. 467, 464-476
12. Brandt, P., Neve, R.L, Kammesheidt, A., Rhoads, R.E. and Vanaman, T.C. (1992) Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels. J. Biol. Chem. 267, 4376-4385
13. 2+-ATPase isoforms in chick cerebellum. Dev. Dyn. 236, 1227-1236
14. Mata, A.M. and Sepulveda, M.R. (2005) Calcium pumps in the central nervous system. Brain Res. Rev. 49, 398-405
15. 2+-ATPase in human brain affected by Alzheimer's disease. FASEB J. 23, 1826-1834
16. Lee, S.J., Liyanage, U., Bickel, P.E., Xia, W., Lansbury, Jr, P.T. and Kosik, K.S. (1998) A detergent-insoluble membrane compartment contains Aβ in vivo. Nat. Med. 4, 730-734
17. Green, K.N., Demuro, A., Akbari, Y., Hitt, B.D., Smith, I.F., Parker, I. and LaFerla, F.M. (2008) SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production. J. Cell Biol. 181, 1107-1116 (Pubitemid 351915486)
18. Duff, K., Eckman, C., Zehr, C., Yu, X., Prada, C.M., Perez-tur, J., Hutton, M., Buee, L., Harigaya, Y., Yager, D. et al. (1996) Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1. Nature 383, 710-713 (Pubitemid 26360645)
19. Larner, A.J. (1997) The cerebellum in Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 8, 203-239
20. 2+ ATPases as dynamic regulators of cellular calcium handling. Ann. N.Y. Acad. Sci. 1099, 226-236
21. Strehler, E.E. and Zacharias, D.A. (2001) Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps. Physiol. Rev. 81, 21-50
22. 2+-ATPase in mouse brain. BMC Neurosci. 10, 112
23. 2+-ATPase isoform 4 is localized in lipid rafts of cerebellum synaptic plasma membranes. J. Biol. Chem. 281, 447-453
24. Brown, D.A. and London, E. (2000) Structure and function of sphingolipidand cholesterol-rich membrane rafts. J. Biol. Chem. 275, 17221-17224
25. Simons, K. and Toomre, D. (2000) Lipid rafts and signal transduction. Nat. Rev. Mol. Cell Biol. 1, 31-39
26. Pike, L.J. (2003) Lipid rafts: bringing order to chaos. J. Lipid Res. 44, 655-667
27. Hering, H., Lin, C.C. and Sheng, M. (2003) Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J. Neurosci. 23, 3262-3271 (Pubitemid 36531967)
28. Legname, G., Nelken, P., Guan, Z., Kanyo, Z.F., DeArmond, S.J. and Prusiner, S.B. (2002) Prion and doppel proteins bind to granule cells of the cerebellum. Proc. Natl. Acad. Sci. U.S.A. 99, 16285-16290
29. Mahfoud, R., Garmy, N., Maresca, M., Yahi, N., Puigserver, A. and Fantini, J. (2002) Identification of a common sphingolipid-binding domain in Alzheimer, prion, and HIV-1 proteins. J. Biol. Chem. 277, 11292-11296
30. Fantini, J. and Yahi, N. (2010) Molecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseases. Expert Rev. Mol. Med. 12, e27
31. Parkin, E.T., Hussain, I., Karran, E.H., Turner, A.J. and Hooper, N.M. (1999) Characterization of detergent-insoluble complexes containing the familial Alzheimer's disease-associated presenilins. J. Neurochem. 72, 1534-1543 (Pubitemid 29140826)
32. Molander-Melin, M., Blennow, K., Bogdanovic, N., Dellheden, B., Mansson, J.E. and Fredman, P. (2005) Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains. J. Neurochem. 92, 171-182 (Pubitemid 40193519)