Synthesis and evaluation of monoamidoxime derivatives: Toward new antileishmanial compounds

European Journal of Medicinal Chemistry

Volumn 46, Issue 7, 2011, Pages 2984-2991

  Paloque, Lucie ^a   Bouhlel, Ahlem ^a   Curti, Christophe ^a   Dumtre, Aurélien ^a   Verhaeghe, Pierre ^a   Azas, Nadine ^a   Vanelle, Patrice ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Amidoxime; Anti infectious; Leishmania donovani; Manganese(III) acetate

Indexed keywords

4 [5 BENZYL 2 (4 BROMOPHENYL) 5 METHYL 4,5 DIHYDROFURAN 3 YLSULFONYL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 2 (4 CHLOROPHENYL) 5 METHYL 4,5 DIHYDROFURAN 3 YLSULFONYL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 2 (4 FLUOROPHENYLSULFONYL) 5 METHYL 4,5 DIHYDROFURAN 3 YLSULFONYL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 2 (4 IODOPHENYL) 5 METHYL 4,5 DIHYDROFURAN 3 YLSULFONYL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 3 (4 BROMOPHENYLSULFONYL) 5 METHYL 4,5 DIHYDROFURAN 2 YL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 3 (4 CHLOROPHENYLSULFONYL) 5 METHYL 4,5 DIHYDROFURAN 2 YL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 3 (4 FLUOROPHENYLSULFONYL) 5 METHYL 4,5 DIHYDROFURAN 2 YL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 3 (4 IODOPHENYLSULFONYL) 5 METHYL 4,5 DIHYDROFURAN 2 YL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 3 (4 METHOXYPHENYLSULFONYL) 5 METHYL 4,5 DIHYDROFURAN 2 YL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 5 METHYL 2 (4 NITROPHENYL) 4,5 DIHYDROFURAN 3 YLSULFONYL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 5 METHYL 2 [4 (TRIFLUOROMETHYL)PHENYL] 4,5 DIHYDROFURAN 3 YLSULFONYL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 5 METHYL 3 (4 NITROPHENYLSULFONYL) 4,5 DIHYDROFURAN 2 YL]N' HYDROXYBENZIMIDAMIDE; 4 [5 BENZYL 5 METHYL 3 [4 (TRIFLUOROMETHYL)PHENYLSULFONYL] 4,5 DIHYDROFURAN 2 YL]N' HYDROXYBENZIMIDAMIDE; AMPHOTERICIN B; ANTILEISHMANIAL AGENT; MANGANESE ACETATE; MANGANESE DERIVATIVE; PENTAMIDINE; UNCLASSIFIED DRUG; ACETIC ACID DERIVATIVE; ANTIPROTOZOAL AGENT; MANGANESE(III) ACETATE DIHYDRATE; ORGANOMETALLIC COMPOUND; OXIME;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; LEISHMANIA DONOVANI; MICROWAVE IRRADIATION; MOUSE; NONHUMAN; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; IC50; LIFE CYCLE STAGE; MACROPHAGE; MICROWAVE RADIATION; PARASITOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ACETATES; AMPHOTERICIN B; ANIMALS; ANTIPROTOZOAL AGENTS; CELL LINE; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; LIFE CYCLE STAGES; MACROPHAGES; MICE; MICROWAVES; ORGANOMETALLIC COMPOUNDS; OXIMES; PENTAMIDINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79957448350     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.04.026     Document Type: Article

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