Synthesis and biological evaluations of novel apocynin analogues

European Journal of Medicinal Chemistry

Volumn 46, Issue 7, 2011, Pages 2691-2698

  Lu, Xiaoyu ^a   Wan, Sainan ^a   Jiang, Jie ^a,b   Jiang, Xiaojian ^a   Yang, Wenjing ^a   Yu, Pei ^a,b   Xu, Lipeng ^a,b   Zhang, Zaijun ^a,b   Zhang, Gaoxiao ^a,b   Shan, Luchen ^a,b   Wang, Yuqiang ^a,b  

^a JINAN UNIVERSITY   (China)

^b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drug Research   (China)

Author keywords

Antioxidant; Apocynin; NADPH oxidase; ROS

Indexed keywords

1 (3 AMINO 4 HYDROXY 5 METHOXYPHENYL)ETHANONE; 1 [3 (5 ACETYL 2 HYDROXY 3 METHOXYBENZYLAMINO) 4 HYDROXY 5 METHOXYPHENYL)ETHANONE; 1 [3 (5 ACETYL 2 HYDROXY 3 METHOXYBENZYLIDENE AMINO) 4 HYDROXY 5 METHOXYPHENYL]ETHANONE; 1 [3 [(BUTYLAMINO)METHYL] 4 HYDROXY 5 METHOXYPHENYL] ETHANONE; 1 [3 [(TERT BUTYLAMINO)METHYL] 4 HYDROXY 5 METHOXY PHENYL]ETHANONE; 1 [3 AMINO 4 (TERT BUTYLDIMETHYLSILYLOXY) 5 METHOXY PHENYL] ETHANONE; 1 [4 HYDROXY 3 METHOXY 5 NITROPHENYL)ETHANONE; 4 ACETYL 2 BUTYRAMIDO 6 METHOXYPHENYL BUTYRATE; 4 ACETYL 2 ISOBUTYRAMIDO 6 METHOXYPHENYL ISOBUTYRATE; 4 ACETYL 2 METHOXY 6 PROPIONAMIDOPHENYL PROPIONATE; AMIDE; AMINE; APOCYNIN; LIPOPOLYSACCHARIDE; N (5 ACETYL 2 HYDROXY 3 METHOXYBENZYLIDENE) 2 METHYLPROPAN 2 AMINE OXIDE; N (5 ACETYL 2 HYDROXY 3 METHOXYPHENYL) 5 (1,2 DITHIOLAN 3 YL)PENTANAMIDE; N (5 ACETYL 2 HYDROXY 3 METHOXYPHENYL)BUTYRAMIDE; N (5 ACETYL 2 HYDROXY 3 METHOXYPHENYL)ISOBUTYRAMIDE; N (5 ACETYL 2 HYDROXY 3 METHOXYPHENYL)PROPIONAMIDE; PROTEIN P67; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID; UNCLASSIFIED DRUG; ACETOPHENONE DERIVATIVE; ANTIOXIDANT; ENZYME INHIBITOR; NEUTROPHIL CYTOSOL FACTOR 67K; PHOSPHOPROTEIN;

ARTICLE; BIOLOGICAL ACTIVITY; CELL PROTECTION; CHEMICAL STRUCTURE; CYTOTOXICITY; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; SYNTHESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MACROPHAGE; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

ACETOPHENONES; ANIMALS; ANTIOXIDANTS; CELL LINE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; THIOCTIC ACID;

EID: 79957440086     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.03.056     Document Type: Article

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