Inhibition of hypoxia-induced retinal neovascularization in mice with short hairpin RNA targeting Rac1, possibly via blockading redox signaling

Experimental Eye Research

Volumn 92, Issue 6, 2011, Pages 473-481

  Zhang, Xiong Ze ^a,b   Huang, Xi ^a   Qiao, Ji Hong ^a   Zhang, Jun Jun ^a   Zhang, Mei Xia ^a  

^a SICHUAN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

HIF 1 ; Hypoxia; NF B; Rac1; Retinal neovascularization; VEGF

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RAC1 PROTEIN; SHORT HAIRPIN RNA; VASCULOTROPIN;

ANGIOGRAPHY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HISTOLOGY; HUMAN; HUMAN CELL; HYPOXIA; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; RETINA NEOVASCULARIZATION; RETINOPATHY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; BLOTTING, WESTERN; DEXTRANS; DISEASE MODELS, ANIMAL; FLUORESCEIN ANGIOGRAPHY; FLUORESCEIN-5-ISOTHIOCYANATE; GENE EXPRESSION; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTRAVITREAL INJECTIONS; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; OXIDATION-REDUCTION; OXYGEN; RAC GTP-BINDING PROTEINS; RETINAL NEOVASCULARIZATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79956369492     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2011.03.005     Document Type: Article

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