Research Progress of the Natural Products against Prostate Cancer

Chinese Journal of Natural Medicines

Volumn 9, Issue 2, 2011, Pages 81-89

  Dong, Fu Yue ^a,b   Jiang, Ren Wang ^a,b  

^a JINAN UNIVERSITY   (China)

^b Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM   (China)

Author keywords

Antitumor; Natural products; Prostate cancer

Indexed keywords

ALKALOID; BETA LAPACHONE; COUMARIN; FLAVONOID; IRIDOID; LIGNAN; NATURAL PRODUCT; PROSTATE SPECIFIC ANTIGEN; QUINONE DERIVATIVE; STAUROSPORINE; UNSATURATED FATTY ACID;

ARTICLE; CANCER CELL CULTURE; HUMAN; PROSTATE CANCER; PROTEIN PHOSPHORYLATION; STRUCTURE ANALYSIS;

EID: 79956324442     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.3724/SP.J.1009.2011.00081     Document Type: Article

References (53)

1. Zhou JR, Yu L, Yu LY, et al. Progression to androgen-independent LNCaP human prostate tumors: cellular and molecular alterations [J]. Int J Cancer 2004, 110(6):800-806.
2. Ye DW, Zhu Y The epidemiological trend of Chinese prostate cancer [J]. Chin Clinl Cancer Education Series 2007, 616-619.
3. Sugiono M, Winkler MH, Okeke AA, et al. Bicalutamide vs cyproterone acetate in preventing flare with LHRH analogue therapy for prostate cancer-a pilot study [J]. Prostate Cancer Prostatic Dis 2005, 8(1):91-94.
4. Bohl CE, Gao W, Miller DD et al. Structural basis for antagonism and resistance of bicalutamide in prostate cancer [J]. Proc Natl Acad Sci USA 2005, 102(17):6201-6206.
5. Jiang RW, Zhou JR, Hon PM, et al. Lignans from Dysosma versipellis with inhibitory effects on prostate cancer cell lines [J]. J Nat Prod 2007, 70(2):283-286.
6. Han HY, Wang XH, Wang NL, et al. Lignans isolated from Campylotropis hirtella (Franch.) Schindl. decreased prostate specific antigen and androgen receptor expression in LNCaP cells [J]. J Agric Food Chem 2008, 56(16):6928-6935.
7. Lee DH, Szczepanski MJ, Lee YJ, et al. Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells [J]. J Cell Bioche 2009, 106(6):1113-1122.
8. Sinha S, Pal BC, Jagadeesh S, et al. Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases [J]. The Prostate 2006, 66(12):1257-1265.
9. Huang DM, Guh JH, Huang YT, et al. Introduction of mitinic aresst and apoptosis in human prostate cancer PC-3 cells by evodiamine [J]. The J Urol 2005, 173(1):256-261.
10. Kan SF, Yu CH, Pu HF, et al. Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3 [J]. J Cell Biochem 2007, 101(1):44-56.
11. Kan SF, Huang WJ, Lin LC, et al. Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP [J]. Int J Cancer 2004, 110(5):641-651.
12. Mantena SK, Sharma SD, Katiyar SK, et al. Berberine, a natural product, induces G1-phase cell cycle arrest and caspase-3-dependent apoptosis in human prostate carcinoma cells [J]. Mol Cancer Ther 2006, 5(2):296-308.
13. Chen K, Hu ZQ, Wang T, et al. Matrine inhibits the proliferation of prostate cancer cells and the activity of androgen receptor [J]. Natl J Androl 2008, 14(8):719-722.
14. Adhami VM, Aziz MH, Reagan SR, et al. Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery [J]. Mol Cancer Ther 2004, 3(8):933-940.
15. Barken I, Geller J, Rogosnitzky M, et al. Noscapine inhibits human prostate cancer progression and metastasis in a mouse model [J]. Anticancer Res 2008, 28(6A):3701-3704.
16. Zhang H, Hoang T, Saeed B, et al. Induction of apoptosis in prostatic tumor cell line DU145 by staurosporine, a potent inhibitor of protein kinases [J]. The Prostate 1996, 29(2):69-76.
17. Qian-Cutrone J, Huang S, Shu YZ, et al. Stephacidin A and B: two structurally novel, selective inhibitors of the testosterone-dependent prostate LNCaP cells[J]. J Am Chem Soc 2002, 124(49):14556-14557.
18. Aalinkeel R, Bindukumar B, Reynols JL, et al. The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90 [J]. Prostate 2008, 68(16):1773-1789.
19. Zhou Q, Yan B, Hu XW, et al. Luteolin inhibits invasion of prostate cancer PC3 cells through E-cadherin [J]. Mol Cancer Ther 2009, 8(6):1684-1691.
20. Jung HJ, Park JW, Jason SL, et al. Silibinin inhibits expression of HIF-1 through suppression of protein translation in prostate cancer cells [J]. Biochem Biophys Res Commun 2009, 390(1):71-76.
21. Flaig TW, Gustafson DL, Su LJ, et al. A phase I and pharma-cokinetic study of silybin-phytosome in prostate cancer patients [J]. Invest New Drugs 2007, 25(2):139-146.
22. Pang XF, Yi TF, Yi ZF, et al. Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting Rho GTPases and extracellular signal-regulated kinase signaling pathways [J]. Cancer Res 2009, 69(2):518-525.
23. Kaur P, Shukla S, Gupta S, et al. Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study [J]. Carcinogenesis 2008, 29(11):2210-2217.
24. Khan N, Asim M, Afaq F, et al. A novel dietary flavonoid fisetin inhibits androgen receptor signaling and tumor growth in athymic nude mice [J]. Cancer Res 2008, 68(20):8555-8563.
25. Khan N, Afaq F, Syed DN, et al. Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells [J]. Carcinogenesis 2008, 29(5):1049-1056.
26. Miocinovic R, McCabe NP, Keck RW, et al. In vivo and in vitro effect of baicalein on human prostate cancer cells [J]. Int J Oncol 2005, 26(1):241-246.
27. Chang HL, Wu Y, Su JH, et al. Protoapigenone, a novel flavonoid, induces apoptosis in human prostate cancer cells through activation of p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase 1/2 [J]. J Pharmaco Exp Ther 2008, 325(3):841-849.
28. Delmulle L, Bellahcene A, Dhoog W, et al. Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines [J]. Phytomedicine 2006, 13(9-10):732-734.
29. Colgate EC, Miranda CL, Stevens JF Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells [J]. Cancer Lett 2007, 246(1-2):201-209.
30. Jung JI, Chung E, Seon MR, et al. Isoliquiritigenin (ISL) inhibits ErbB3 signaling in prostate cancer cells [J]. Biofactors 2006, 28(3-4):159-168.
31. Kanazawa M, Satomi Y, Mizutani Y, et al. Isoliquiritigenin inhibits the growth of prostate cancer [J]. Eur Urol 2003, 43(5):580-586.
32. Jung JI, Lim SS, Choi HJ, et al. Isoliquiritigenin induces apoptosis by depolarizing mitochondrial membranes in prostate cancer cells [J]. J Nutri Biochem 2006, 17(10):689-696.
33. Yo YT, Shieh GS, Hsu KF, et al. Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway [J]. J Agric Food Chem 2009, 57(18):8266-8273.
34. Fu Y, Hsieh TC, Guo J, et al. Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells [J]. Biochem Biophys Res Commun 2004, 322:263-270.
35. Han HY, Wen P, Liu HW, et al. Coumarins from Campylotropis hirtella (FRANCH.) SCHINDL and their inhibitory activity on prostate specific antigen secreted from LNCaP cells [J]. Chem Pharm Bull 2008, 56(9):1338-1341.
36. Kang TJ, Lee SY, Singh RP, et al. Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells [J]. Acta Oncol 2009, 48(6):895-900.
37. Kang J, Lee S, Yim D Effect of isoimperatorin on the proliferation of prostate cancer cell line DU145 cells [J]. J Appl Pharmacol 2005, 13(3):185-189.
38. Yim D, Singh RP, Agarwal C, et al. A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells [J]. Cancer Res 2005, 65(3):1035-1044.
39. Rivière C, Goossens L, Pommery N, et al. Antiproliferative effects of isopentenylated coumarins isolated from Phellolo-phium madagascariense Baker [J]. Nat Prod Res, Part A: Structure and Synthesis 2006, 20(10):909-916.
40. Sung B, Park B, Yadav VR, et al. Celastrol, a triterpene extracted from the Chinese " thunder of god vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice [J]. Cancer Res 2006, 66(9):4758-4765.
41. Chintharlapalli S, Papineni S, Ramaiah SK, et al. Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors [J]. Cancer Res 2007, 67(6):2816-2823.
42. Kassi E, Papoutsi Z, Pratsinis H, et al. Ursolic acid, a naturally occurring triterpenoid, demonstrates anticancer activity on human prostate cancer cells [J]. J Cancer Res Clin Oncol 2007, 133:493-500.
43. Saleem M, Murtaza I, Witkowsky O, et al. Lupeol triterpene, a novel diet-based microtubule targeting agent: Disrupts survivin/cFLIP activation in prostate cancer cells [J]. Biochem Biophys Res Commun 2009, 388(3):576-582.
44. Estrada AC, Syrovets T, Pitterle K, et al. Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells [J]. Mol Pharmacol 2010, 77(3):378-387.
45. Loizzo MR, Tundis R, Statti GA, et al. Jacaranone: a cytotoxic constituent from Senecio ambiguus subsp. ambiguus (biv.) DC. against renal adenocarcinoma ACHN and prostate carcinoma LNCaP cells [J]. Arch pharmacal Res 2007, 30(6):701-707.
46. Dumont P, Ingrassia L, Rouzeau S, et al. The Amaryllidaceae isocarbostyril narciclasine induces apoptosis by activation of the death receptor and/or mitochondrial pathways in cancer cells but not in normal fibroblasts [J]. Neoplasia 2007, 9(9):766-776.
47. Choi YH, Kang HS, Yoo MA, et al. Suppression of human prostate cancer cell growth by β-lapachone via down-regulation of pRB phosphorylation and induction of Cdk inhibitor p21WAF1/CIP1 [J]. J Biochem Mol Biol 2003, 36(2):223-229.
48. Xie G, Zhu X, Li Q SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway [J]. Br J Pharmacol 2010, 159(3):689-697.
49. Lin S, Shen YH, Li HL, et al. Acylated iridoids with cytotoxicity from Valeriana jatamansi [J]. J Nat Prod 2009, 72:650-655.
50. Krohn K, Gehle D, Dey SK, et al. Prismatomerin, a new iridoid from Prismatomeris tetrandra. Structure elucidation, determination of absolute configuration, and cytotoxicity [J]. J Nat Prod 2007, 70:1339-1343.
51. Ghosh J, Myers CE Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells [J]. Proc Nat Acad Sci USA 1998, 95:13182-13187.
52. Cesano A, Visonneau S, Scimeca JA, et al. Opposite effects of linoleic acid and conjugated linoleic acid on human prostatic cancer in SCID mice [J]. Anticancer Res 1998, 18:1429-1434.
53. Jiang RW, Hay ME, Fairchild CR, et al. Antineoplastic unsaturated fatty acids from Fijian macroalgae [J]. Phytochemistry 2008, 69:2495-2500.