Induction of apoptosis in prostatic tumor cell line DU145 by staurosporine, a potent inhibitor of protein kinases

Prostate

Volumn 29, Issue 2, 1996, Pages 69-76

  Zhang, Haichao ^a   Hoang, Thuc ^a   Saeed, Badr ^a   Ng, Shi Chung ^a,b  

^a ABBOTT LABORATORIES   (United States)

^b Abbott   (France)

Author keywords

apoptosis; bcl 2; DU145; staurosporine

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; PROTEIN KINASE INHIBITOR; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; ENZYME INHIBITION; GENE EXPRESSION; GROWTH INHIBITION; HORMONAL REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE INDUCTION;

ALKALOIDS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CAENORHABDITIS ELEGANS PROTEINS; CARCINOMA; CASPASE 2; CASPASES; CELL DIVISION; CELL SURVIVAL; DNA, NEOPLASM; DOWN-REGULATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS; PROTEIN KINASE INHIBITORS; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REPRESSOR PROTEINS; STAUROSPORINE; TIME FACTORS; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0029847565     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(199608)29:2<69::AID-PROS1>3.0.CO;2-C     Document Type: Article

References (29)

1. Boring CC, Squires TS, Tong T: Cancer statistics 1993. CA Cancer J Clin 43:7-26, 1993.
2. Schally AV, Redding TW, Comaru-Schally AM: Inhibition of prostate tumors by agonistic and antagonistic analogs of LH-RH. Prostate 4:545-552, 1983.
3. Wyllie AH, Kerr JFR, Currie AR: Cell death: The significance of apoptosis. Int Rev Cytol 68:251-306, 1986.
4. Kyprianou N, English HF, Isaacs JT: Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation. Cancer Res 50:3748-3753, 1990.
5. Kyprianou N, Bains AK, Jacobs SC: Induction of apoptosis in androgen-independent human prostate cancer cells undergoing thymineless death. Prostate 25:66-75, 1994.
6. Furuya Y, Lundmo P, Short AD, Gill DL, Isaacs JT: The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin. Cancer Res 54:6167-6175, 1994.
7. Stone KR, Mickey DD, Wunderli H, Mickey GH, Paulson DF: Isolation of a human prostate carcinoma cell line (DU145). Int J Cancer 21:274-281, 1978.
8. 3H]-staurosporine on various protein kinases. Biochem Biophys Res Commun 171: 189-195, 1990.
9. ++ dependent protein kinase. Biochem Biophys Res Commun 135:397-402, 1986.
10. Th'ng JPH, Guo X-W, Swank RA, Crissman HA, Bradbury EM: Inhibition of histone phosphorylation by Staurosporine leads to chromosome decondensation. J Biol Chem 269:9568-9573, 1994.
11. Jacobson MD, Burne FJ, Raff MC: Programmed cell death and bcl-2 protection in the absence of a nucleus. EMBO J 90:1899-1910, 1994.
12. Cleary ML, Smith SD, Sklar J: Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell 47:19-28, 1986.
13. Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G, Thompson CB: Bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597-608, 1993.
14. Oltvai ZN, Milliman CL, Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death. Cell 74:609-619, 1993.
15. Cerretti DP, Kozlosky CJ, Mosley B, Nelson N, Van NK, Greenstreet TA, March CJ, Kronheim SR, Druck T, Cannizzaro LA, Huebner K, Black RA: Molecular cloning of the interleukin-1β converting enzyme. Science 256:97-100, 1992.
16. Wang L, Miura M, Bergeron L, Zhu H, Yuan J: Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78:739-750, 1994.
17. Nakashima T, Sekiguchi T, Kuraoka A, Fukushima K, Shibata Y, Komiyama S, Nishimoto T: Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells. Mol Cell Biol 13:6367-6374, 1993.
18. Moore KJ, Matlashewski G: Intracellular infection by Leishmania donovani inhibits macrophage apoptosis. J Immunol 152:2930-2937, 1994.
19. Freeman RS, Estus S, EM, Johnson S: Analysis of cell cycle-related gene expression in postmitotic neurons: Selective induction of cyclin D1 during programmed cell death. Neuron 12:343-355, 1994.
20. Cleveland DW, Lopata MA, McDonald RJ, Cowan NJ, Rutter WJ, Kishner MN: Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes. Cell 20:95-105, 1980.
21. Reed J, Stein C, Subasinghe C, Haldar S, Croce CM, Yum S, Cohen J: Antisense-mediated Inhibition of bcl-2 protooncogene expression and leukemic cell growth and survival: Comparisons of phosphodiester and phosphorothioate oligodeoxynucleotides. Cancer Res 50:6565-6570, 1990.
22. Jacobson MD, Burne JF, King MP, Miyashita T, Reed JC, Raff MC: Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA. Nature 361:365-369, 1993.
23. Yousefi S, Green DR, Blaser K, Simon H-U: Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc Natl Acad Sci USA 91:10868-10872, 1994.
24. Walker PR, Kwast-Welfeld J, Gourdeau H, Leblanc J, Neugebauer W, Sikorska M: Relationship between apoptosis and the cell cycle in lymphocytes: Role of protein kinase C, tyrosine phosphorylation, and AP1. Exp Cell Res 207:142-151, 1993.
25. Oltvai ZN, Korsmeyer SJ: Checkpoints of dueling dimers foil death wishes. Cell 79:189-192, 1994.
26. Zhang H, Saeed B, Ng S: Combinatorial interaction of human BCL-2 related proteins: Mapping of regions important for BCL-2/BCL-X-S interaction. Biochem Biophys Res Commun 208:950-956, 1995.
27. Furuya Y, Isaacs JT: Proliferation-dependent vs. independent programmed cell death of prostatic cancer cells involves distinct gene regulation. Prostate 25:301-309, 1994.
28. Buttyan R, Olsson CA, Pintar J, Chang C, Bandyk M, Ng P-Y, Sawczuk IS: Induction of TRPM-2 gene in cells undergoing programmed cell death. Mol Cell Biol 9:3473-3481, 1989.
29. Colombel M, Symmans F, Gil S, O'Toole KM, Chopin D, Benson M, Olsson CA, Korsmeyer S, Buttyan R: Detection of the apoptosis-suppressing oncoprotein bcl-2 in hormone-refractory human prostate cancers. Am J Pathol 143:390-399, 1993.