High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase

Nature Medicine

Volumn 7, Issue 7, 2001, Pages 853-857

  Yuhanna, Ivan S ^a   Zhu, Yan ^b   Cox, Blair E ^a   Hahner, Lisa D ^a   Osborne Lawrence, Sherri ^a   Lu, Ping ^b   Marcel, Yves L ^c   Anderson, Richard G W ^d   Mendelsohn, Michael E ^b   Hobbs, Helen H ^a   Shaul, Philip W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SCAVENGER RECEPTOR;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CHO CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING;

ANIMALS; ANTIGENS, CD36; BASE SEQUENCE; CELL LINE, TRANSFORMED; CHO CELLS; CRICETINAE; DNA PRIMERS; ENZYME ACTIVATION; LIPOPROTEINS, HDL; MEMBRANE PROTEINS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCAVENGER RECEPTORS, CLASS B; SHEEP;

EID: 0034927750     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/89986     Document Type: Article

References (35)

1. High-density lipoprotein-the clinical implications of recent studies
2. The "best" of cholesterols, the "worst" of cholesterols: A tale of two receptors
3. Endothelial dysfunction in atherosclerosis
4. The role of nitric oxide and other endothelium-derived vasoactive substances in vascular disease
5. Decreased basal nitric oxide release in hypercholesterolemia increases neutrophil adherence to rabbit coronary artery endothelium
6. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits
7. Nitric oxide as a signaling molecule in the vascular system: An overview
8. Role of plasmalemmal caveolae in signal transduction
9. Genetic mutations affecting human lipoproteins, their receptors, and their enzymes
10. Receptor-mediated endocytosis of low density lipoprotein: Somatic cell mutants define multiple genes required for expression of surface-receptor activity
11. Scavenger receptor, class B, type I-dependent stimulation of cholesterol esterification by high density lipoproteins, low density lipoproteins, and nonlipoprotein cholesterol
12. Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae
13. High density lipoprotein prevents oxidized low density lipoprotein-induced inhibition of endothelial nitric oxide synthase localization and activation in caveolae
14. ER-α and eNOS are organized into a functional signaling module in caveolae
15. Binding of high density lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger receptor class B type I
16. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism
17. High density lipoprotein receptors, binding proteins, and ligands
18. Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology
19. Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoproteinor apolipoprotein A-I concentration
20. High density lipoproteins interrupt the sphingosine kinase pathway
21. Atherosclerosis- an inflammatory disease
22. Identification of scavenger receptor SR-BI as high density lipoprotein receptor
23. Transport of lipids from high and low density lipoproteins via scavenger receptor-BI
24. Scavenger receptor class B, type I, mediates selective uptake of low density lipoprotein cholesteryl ester
25. Expression of scavenger receptor BI in COS-7 cells alters cholesterol content and distribution
26. Expression of scavenger receptor class B type 1 promotes microvillar channel formation and selective cholesteryl ester transport in a heterologous reconstituted system
27. Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I
28. Establishment of an immortalized fetal intrapulmonary artery endothelial cell line
29. Acylation targets endothelial nitric oxide synthase to plasmalemmal caveolae
30. Characterization of human apolipoprotein A-I expressed in Escherichia coli
31. Isolation and quantitation of apolipoproteins A-I and A-II from human high -density lipoproteins by fast-protein liquid chromatography
32. Estrogen upregulates cyclooxygenase-1 gene expression in ovine fetal pulmonary artery endothelium
33. Basal release of nitric oxide in mouse aortic rings is inhibited by antiestrogens but not affected by estrogen receptor beta
34. Oxygen modulates endothelium-derived relaxing factor production in fetal pulmonary arteries
35. Basal release of nitric oxide from aortic rings is greater in female rabbits than male rabbits: Implications for atherosclerosis