NeuroD factors regulate cell fate and neurite stratification in the developing retina

Journal of Neuroscience

Volumn 31, Issue 20, 2011, Pages 7365-7379

  Cherry, Timothy J ^a   Wang, Sui ^a,b   Bormuth, Ingo ^b,c   Schwab, Markus ^b   Olson, James ^d   Cepko, Constance L ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; NEUROGENIC DIFFERENTIATION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FATE; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEUROD2 GENE; NEUROD6 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RETINA AMACRINE CELL; RETINA DEVELOPMENT; RETINA INNER PLEXIFORM LAYER; TARGET CELL;

AMACRINE CELLS; ANIMALS; ANIMALS, NEWBORN; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; FEMALE; GAMMA-AMINOBUTYRIC ACID; GENE KNOCK-IN TECHNIQUES; GLYCINE; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURITES; NEUROGENESIS; NEUROPEPTIDES; RETINA; STEM CELLS;

EID: 79956291837     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2555-10.2011     Document Type: Article

References (45)

1. Baumgardt M, Karlsson D, Terriente J, Díaz-Benjumea FJ, Thor S (2009) Neuronal subtype specification within a lineage by opposing temporal feed-forward loops. Cell 139:969-982.
2. Bertrand N, Castro DS, Guillemot F (2002) Proneural genes and the specification of neural cell types. Nat Rev Neurosci 3:517-530.
3. Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL (2004) Genomic analysis of mouse retinal development. PLoS Biol 2:E247.
4. Bloomfield SA, Dacheux RF (2001) Rod vision: pathways and processing in the mammalian retina. Prog Retin Eye Res 20:351-384.
5. Bramblett DE, Pennesi ME, Wu SM, Tsai MJ (2004) The transcription factor Bhlhb4 is required for rod bipolar cell maturation. Neuron 43:779-793.
6. Cai L, Morrow EM, Cepko CL (2000) Misexpression of basic helix-loophelix genes in the murine cerebral cortex affects cell fate choices and neuronal survival. Development 127:3021-3030.
7. Cepko CL (1999) The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates. Curr Opin Neurobiol 9:37-46.
8. Cherry TJ, Trimarchi JM, Stadler MB, Cepko CL (2009) Development and diversification of retinal amacrine interneurons at single cell resolution. Proc Natl Acad Sci U S A 106:9495-9500.
9. Chien CT, Hsiao CD, Jan LY, Jan YN (1996) Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes. Proc Natl Acad Sci U S A 93:13239-13244.
10. Feng L, Xie X, Joshi PS, Yang Z, Shibasaki K, Chow RL, Gan L (2006) Requirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retina. Development 133:4815-4825.
11. Fuerst PG, Koizumi A, Masland RH, Burgess RW (2008) Neurite arborization and mosaic spacing in the mouse retina require DSCAM. Nature 451:470-474.
12. Fuerst PG, Bruce F, Tian M, Wei W, Elstrott J, Feller MB, Erskine L, Singer JH, Burgess RW (2009) DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina. Neuron 64:484-497.
13. Gaudillière B, Konishi Y, de la Iglesia N, Yao G, Bonni A (2004) A CaMKII Neuro Dsignaling pathway specifies dendritic morphogenesis. Neuron 41:229-241.
14. Goebbels S, Bormuth I, Bode U, Hermanson O, Schwab MH, Nave KA (2006) Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis 44:611-621.
15. Gradwohl G, Fode C, Guillemot F (1996) Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors. Dev Biol 180:227-241.
16. Guillemot F (2007) Spatial and temporal specification of neural fates by transcription factor codes. Development 134:3771-3780.
17. Hatakeyama J, Kageyama R (2004) Retinal cell fate determination and bHLH factors. Semin Cell Dev Biol 15:83-89.
18. Hatakeyama J, Tomita K, Inoue T, Kageyama R (2001) Roles of homeobox and bHLH genes in specification of a retinal cell type. Development 128:1313-1322.
19. Hobert O (2008) Regulatory logic of neuronal diversity: terminal selector genes and selector motifs. Proc Natl Acad Sci U S A 105:20067-20071.
20. Ince-Dunn G, Hall BJ, Hu SC, Ripley B, Huganir RL, Olson JM, Tapscott SJ, Ghosh A (2006) Regulation of thalamocortical patterning and synaptic maturation by Neuro D2. Neuron 49:683-695.
21. Inoue T, Hojo M, Bessho Y, Tano Y, Lee JE, Kageyama R (2002) Math3 and Neuro D regulate amacrine cell fate specification in the retina. Development 129:831-842.
22. Jukam D, Desplan C (2010) Binary fate decisions in differentiating neurons. Curr Opin Neurobiol 20:6-13.
23. Kim DS, Ross SE, Trimarchi JM, Aach J, Greenberg ME, Cepko CL (2008) Identification of molecular markers of bipolar cells in the murine retina. J Comp Neurol 507:1795-1810.
24. Ledent V, Paquet O, Vervoort M (2002) Phylogenetic analysis of the human basic helix-loop-helix proteins. Genome Biol 3:RESEARCH0030.
25. Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, Weintraub H (1995) Conversion of Xenopus ectoderm into neurons by Neuro D, a basic helixloop-helix protein. Science 268:836-844.
26. Ma YC, Song MR, Park JP, Henry Ho HY, Hu L, Kurtev MV, Zieg J, Ma Q, Pfaff SL, Greenberg ME (2008) Regulation of motor neuron specification by phosphorylation of neurogenin 2. Neuron 58:65-77.
27. Masland RH (2001) Neuronal diversity in the retina. Curr Opin Neurobiol 11:431-436.
28. Masland RH (2004) Neuronal cell types. Curr Biol 14:R497-R500.
29. Matsuda T, Cepko CL (2004) Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc Natl Acad Sci U S A 101:16-22.
30. Matsuoka RL, Nguyen-Ba-Charvet KT, Parray A, Badea TC, Chédotal A, Kolodkin AL (2011) Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina. Nature 470:259-263.
31. Miyata T, Maeda T, Lee JE (1999) Neuro D is required for differentiation of the granule cells in the cerebellum and hippocampus. Genes Dev 13:1647-1652.
32. Morrow EM, Furukawa T, Lee JE, Cepko CL (1999) Neuro D regulates multiple functions in the developing neural retina in rodent. Development 126:23-36.
33. Münch TA, da Silveira RA, Siegert S, Viney TJ, Awatramani GB, Roska B (2009) Approach sensitivity in the retina processed by a multifunctional neural circuit. Nat Neurosci 12:1308-1316.
34. Olson JM, Asakura A, Snider L, Hawkes R, Strand A, Stoeck J, Hallahan A, Pritchard J, Tapscott SJ (2001) Neuro D2 is necessary for development and survival of central nervous system neurons. Dev Biol 234:174-187.
35. Roesch K, Jadhav AP, Trimarchi JM, Stadler MB, Roska B, Sun BB, Cepko CL (2008) The transcriptome of retinal Muller glial cells. J Comp Neurol 509:225-238.
36. Salic A, Mitchison TJ (2008) Achemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A 105:2415-2420.
37. Sanes JR, Zipursky SL (2010) Design principles of insect and vertebrate visual systems. Neuron 66:15-36.
38. Schwab MH, Bartholomae A, Heimrich B, Feldmeyer D, Druffel-Augustin S, Goebbels S, Naya FJ, Zhao S, Frotscher M, Tsai MJ, Nave KA (2000) Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus. J Neurosci 20:3714-3724.
39. Sommer L, Ma Q, Anderson DJ (1996) Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol Cell Neurosci 8:221-241.
40. Soriano P (1999) Generalized lac Z expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71.
41. Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL (2007) Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol 502:1047-1065.
42. Trimarchi JM, Stadler MB, Cepko CL (2008) Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One 3:e1588.
43. Yamagata M, Weiner JA, Sanes JR (2002) Sidekicks: synaptic adhesion molecules that promote lamina-specific connectivity in the retina. Cell 110:649-660.
44. Yang Y, Kim AH, Yamada T, Wu B, Bilimoria PM, Ikeuchi Y, de la Iglesia N, Shen J, Bonni A (2009) A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. Science 326:575-578.
45. Young RW (1985) Cell differentiation in the retina of the mouse. Anat Rec 212:199-205.