T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading

Journal of Clinical Immunology

Volumn 24, Issue 4, 2004, Pages 327-339

  Ott, Patrick A ^a   Dittrich, Marcus T ^a,b   Herzog, Bernhard A ^a,b   Guerkov, Robert ^a   Gottlieb, Peter A ^c   Putnam, Amy L ^c   Durinovic Bello, Ivana ^b   Boehm, Bernhard O ^b   Tary Lehmann, Magdalena ^a   Lehmann, Paul V ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY HOSPITAL ULM   (Germany)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

Autoimmunity; Cytokines; Diabetes; Peptides; T lymphocytes

Indexed keywords

ANTIBODY; AUTOANTIGEN; CD28 ANTIGEN; CELL ANTIGEN; EPITOPE; GAMMA INTERFERON; GLUTAMATE DEHYDROGENASE; ISOENZYME; PEPTIDE; PROINSULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HEALTH STATUS; HIGH RISK PATIENT; HLA MATCHING; HUMAN; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MEMORY CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANTIGENIC VARIATION; AUTOANTIGENS; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 1; EPITOPES; GLUTAMATE DECARBOXYLASE; HISTOCOMPATIBILITY TESTING; HUMANS; IMMUNOLOGIC MEMORY; ISOENZYMES; LYMPHOCYTE COUNT; PEPTIDE FRAGMENTS; PROINSULIN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

EID: 3442880270     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:JOCI.0000029120.77824.41     Document Type: Article

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