A novel redox-based switch: LMW-PTP oxidation enhances Grb2 binding and leads to ERK activation

Biochemical and Biophysical Research Communications

Volumn 348, Issue 2, 2006, Pages 367-373

  Giannoni, Elisa ^a   Raugei, Giovanni ^a,b   Chiarugi, Paola ^a,b   Ramponi, Giampietro ^a,b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Center of Excellence for Scientific Research DENOTHE   (Italy)

Author keywords

ERK; Grb2; LMW PTP; Oxidative stress; Reactive oxygen species

Indexed keywords

ADAPTOR PROTEIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; ENZYME INACTIVATION; MOLECULAR WEIGHT; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GRB2 ADAPTOR PROTEIN; HUMANS; ISOENZYMES; MICE; NIH 3T3 CELLS; OXIDATION-REDUCTION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; TYROSINE; ULTRAVIOLET RAYS;

EID: 33746913858     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.091     Document Type: Article

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