Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation

Journal of Virology

Volumn 85, Issue 11, 2011, Pages 5338-5349

  Córdoba, Laura ^a   Huang, Yao Wei ^a   Opriessnig, Tanja ^b   Harral, Kylie K ^a   Beach, Nathan M ^a   Finkielstein, Carla V ^c   Emerson, Suzanne U ^d   Meng, Xiang Jin ^a  

^a CENTER FOR MOLECULAR MEDICINE AND INFECTIOUS DISEASES   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; CONTROLLED STUDY; HEPATITIS E VIRUS; HUMAN; HUMAN CELL; INTESTINE; LIVER; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; SEROCONVERSION; SWINE; VIREMIA; VIRUS ATTENUATION; VIRUS MUTANT; VIRUS MUTATION; VIRUS SHEDDING; VIRUS VIRULENCE;

AMINO ACIDS; ANIMALS; BLOOD; CAPSID PROTEINS; CELL LINE; DISEASE MODELS, ANIMAL; FECES; HEPATITIS E; HEPATITIS E VIRUS; HEPATOCYTES; HUMANS; MUTATION, MISSENSE; SWINE; SWINE DISEASES; VIREMIA; VIRULENCE; VIRUS SHEDDING;

HEPATITIS E VIRUS; MIRIDAE; SUIDAE;

EID: 79956156476     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02278-10     Document Type: Article

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