Regulation of the high basal expression of the manganese superoxide dismutase gene in aggressive breast cancer cells

Free Radical Biology and Medicine

Volumn 50, Issue 12, 2011, Pages 1771-1779

  Ennen, Marie ^a   Minig, Vanessa ^a   Grandemange, Stéphanie ^a   Touche, Nadège ^a   Merlin, Jean Louis ^a,b   Besancenot, Vanessa ^a   Brunner, Emilie ^a   Domenjoud, Lionel ^a   Becuwe, Philippe ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b Lorraine Institute of Cancerology   (France)

Author keywords

Breast cancer; Damaged DNA binding 2; Free radicals; Histone modifications; Manganese superoxide dismutase; NF B; Sp1; Transcription

Indexed keywords

HISTONE H3; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PEPTIDE; PROTEIN P50; SYNAPTOTAGMIN I;

ACETYLATION; ARTICLE; BREAST CANCER; CANCER CELL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; UPREGULATION;

ACETYLATION; BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; FEMALE; FREE RADICALS; HISTONES; HUMANS; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROMOTER REGIONS, GENETIC; RETROSPECTIVE STUDIES; SP1 TRANSCRIPTION FACTOR; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 79956146961     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.03.013     Document Type: Article

References (29)

1. J.M. Matés Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology Toxicology 153 2000 83 104
2. L. Miao, and D.K. St Clair Regulation of superoxide dismutase genes: implications in disease Free Radic. Biol. Med. 47 2009 344 356
3. K.K. Nelson, A.C. Ranganathan, J. Mansouri, A.M. Rodriguez, K.M. Providence, J.L. Rutter, K. Pumiglia, J.A. Bennett, and J.A. Melendez Elevated sod2 activity augments matrix metalloproteinase expression: evidence for the involvement of endogenous hydrogen peroxide in regulating metastasis Clin. Cancer Res. 9 2003 424 432 (Pubitemid 36109760)
4. K.K. Kiningham, and D.K. St Clair Overexpression of manganese superoxide dismutase selectively modulates the activity of Jun-associated transcription factors in fibrosarcoma cells Cancer Res. 57 1997 5265 5271 (Pubitemid 27516361)
5. L.A. Ridnour, T.D. Oberley, and L.W. Oberley Tumor suppressive effects of MnSOD overexpression may involve imbalance in peroxide generation versus peroxide removal Antioxid. Redox Signal. 6 2004 501 512 (Pubitemid 38625371)
6. Z. Kattan, V. Minig, P. Leroy, M. Dauça, and P. Becuwe Role of manganese superoxide dismutase on growth and invasive properties of human estrogen-independent breast cancer cells Breast Cancer Res. Treat. 108 2008 203 215 (Pubitemid 351311363)
7. C. Zhu, Y. Huang, C.J. Weydert, L.W. Oberley, and F.E. Domann Constitutive activation of transcription factor AP-2 is associated with decreased MnSOD expression in transformed human lung fibroblasts Antioxid. Redox Signal. 3 2001 387 395 (Pubitemid 32646030)
8. V. Minig, Z. Kattan, J. van Beeumen, E. Brunner, and P. Becuwe Identification of DDB2 protein as a transcriptional regulator of constitutive SOD2 gene expression in human breast cancer cells J. Biol. Chem. 284 2009 14165 14176
9. J. Tang, and G. Chu Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein DNA Repair 1 2002 601 616 (Pubitemid 34765611)
10. Y. Xu, S. Porntadavity, and D.K. St Clair Transcriptional regulation of the human manganese superoxide dismutase gene: the role of the specificity protein 1 (Sp1) and activating protein-2 (AP-2) Biochem. J. 362 2002 401 412 (Pubitemid 34214483)
11. P.L. Jones, D. Ping, and J.M. Boss Tumor necrosis factor alpha and interleukin-1b regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-β and NF-κB Mol. Cell. Biol. 17 1997 6970 6981 (Pubitemid 27505927)
12. F. Hirano, H. Tanaka, Y. Hirano, M. Hiramoto, H. Handa, I. Makino, and C. Scheidereit Functional interference of Sp1 and NF-kappaB through the same DNA binding site Mol. Cell. Biol. 18 1998 1266 1274 (Pubitemid 28100890)
13. N. Yamaguchi, T. Ito, S. Azuma, E. Ito, R. Honma, Y. Yanagisawa, A. Nishikawa, M. Kawamura, J. Imai, S. Watanabe, K. Semba, and J. Inoue Constitutive activation of nuclear factor-kappaB is preferentially involved in the proliferation of basal-like subtype breast cancer cell lines Cancer Sci. 100 2009 1668 1674
14. Z. Kattan, S. Marchal, E. Brunner, C. Ramacci, A. Leroux, J.L. Merlin, L. Domenjoud, M. Dauça, and P. Becuwe Damaged DNA binding protein 2 plays a role in breast cancer cell growth PLoS ONE 3 2008 e2002
15. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
16. M.I. Olnes, and R.N. Kurl Isolation of nuclear extracts from fragile cells: a simplified procedure applied to thymocytes Biotechniques 17 1994 828 829 (Pubitemid 24345991)
17. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J. Biol. Chem. 193 1951 265 275
18. H.P. Kim, J.H. Roe, P.B. Chock, and M.B. Yim Transcriptional activation of the human manganese superoxide dismutase gene mediated by tetradecanoylphorbol acetate J. Biol. Chem. 274 1999 37455 37460
19. D. Bernard, B. Quatannens, A. Begue, B. Vandenbunder, and C. Abbadie Antiproliferative and antiapoptotic effects of c-rel may occur within the same cells via the up-regulation of manganese superoxide dismutase Cancer Res. 61 2001 2656 2664 (Pubitemid 32685852)
20. Y.Z. Lin, S. Yao, R.A. Veach, T.R. Torgerson, and J. Hawiger Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence J. Biol. Chem. 270 1995 14255 14258
21. K.K. Nelson, and J.A. Melendez Mitochondrial redox control of matrix metalloproteinases Free Radic. Biol. Med. 37 2004 768 784 (Pubitemid 39078549)
22. M.J. Hitchler, K. Wikainapakul, L. Yu, K. Powers, W. Attatippaholkun, and F.E. Domann Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells Epigenetics 1 2006 163 171
23. I. Lacroix, C. Lipcey, J. Imbert, and B. Kahn-Perlès Sp1 transcriptional activity is up-regulated by phosphatase 2A in dividing T lymphocytes J. Biol. Chem. 277 2002 9598 9605 (Pubitemid 34953049)
24. W.S. Dynan, and R. Tjian The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter Cell 35 1983 79 87 (Pubitemid 14240221)
25. Y. Xu, K.K. Kiningham, M.N. Devalaraja, C.C. Yeh, H. Majima, E.J. Kasarskis, and D.K. St Clair An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta DNA Cell Biol. 18 1999 709 722 (Pubitemid 29439223)
26. X.S. Wan, M.N. Devalaraja, and D.K. St Clair Molecular structure and organization of the human manganese superoxide dismutase gene DNA Cell Biol. 13 1994 1127 1136 (Pubitemid 24373847)
27. Z. Guo, G.H. Boekhoudt, and J.M. Boss Role of the intronic enhancer in tumor necrosis factor-mediated induction of manganous superoxide dismutase J. Biol. Chem. 278 2003 23570 23578 (Pubitemid 36830177)
28. M.J. Hitchler, L.W. Oberley, and F.E. Domann Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells Free Radic. Biol. Med. 45 2008 1573 1580
29. Y. Xu, F. Fang, S.K. Dhar, W.H. St Clair, E.J. Kasarskis, and D.K. St Clair The role of a single-stranded nucleotide loop in transcriptional regulation of the human sod2 gene J. Biol. Chem. 282 2007 15981 15994 (Pubitemid 47100336)