Overexpression of manganese superoxide dismutase selectively modulates the activity of jun-associated transcription factors in fibrosarcoma cells

Cancer Research

Volumn 57, Issue 23, 1997, Pages 5265-5271

  Kiningham, Kelley K ^a   St Clair, Daret K ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CANCER INHIBITION; CARCINOGENICITY; ENZYME ACTIVITY; FIBROSARCOMA; GENE EXPRESSION; GENE TARGETING; MOUSE; NONHUMAN; ONCOGENE C JUN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN BINDING; TUMOR SUPPRESSOR GENE;

ANIMALS; BCL-X PROTEIN; CLONE CELLS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FIBROSARCOMA; GENES, TUMOR SUPPRESSOR; LUCIFERASES; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-JUN; RECOMBINANT FUSION PROTEINS; SUPEROXIDE DISMUTASE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

EID: 0030722538     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Sun, Y. Free radicals, antioxidant enzymes, and carcinogenesis. Free Radical Biol. Med., 8: 583-599, 1990.
2. Oberley, L. W., and Buettner, G. R. Role of Superoxide dismutase in cancer: a review. Cancer Res., 39: 1141-1149, 1979.
3. St. Clair, D. K., Oberley, T. D., Muse, K. E., and St. Clair, W. H. Expression of manganese superoxide dismutase promotes cellular differentiation. Free Radical Biol. Med., 16: 275-292, 1994.
4. St. Clair, D. K., Wan, X. S., Oberley, T. D., Muse, K. E., and St. Clair, W. H. Suppression of radiation-induced neoplastic transformation by overexpression of mitochondrial superoxide dismutase. Mol. Carcinog., 6: 238-242, 1992.
5. Yan, T., Oberley, L. W., Zhong, W., and St. Clair, D. K. Manganese-containing superoxide dismutase overexpression causes phenotypic reversion in SV40-transformed human lung fibroblasts. Cancer Res., 56: 2864-2871, 1996.
6. Li, J. J., Oberley, L. W., St. Clair, D. K., Ridnour, L. A., and Oberley, T. D. Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase. Oncogene, 10: 1989-2000, 1995.
7. Church, S. L., Grant, J. W., Ridnour, L. A., Oberley L. W., Swanson, P. E., Meltzer, P. S., and Trent, J. M. Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Proc. Natl. Acad. Sci. USA, 90: 3113-3117, 1993.
8. St. Clair, D. K., Wan, X. S., Kuroda, M., Vichitbandha, S., Tsuchida, E., and Urano, M. Suppression of tumor metastasis by manganese superoxide dismutase is associated with reduced tumorigenicity and elevated fibronectin. Oncol. Rep., 4: 753-757, 1997.
9. Safford, S. E., Oberley, T. D., Urano, M., and St. Clair, D. K. Suppression of fibrosarcoma metastasis by elevated expression of manganese superoxide dismutase. Cancer Res., 54: 4261-4265, 1994.
10. Roos, E. Cellular adhesion, invasion and metastasis. Biochim. Biophys. Acta, 738: 263-284, 1984.
11. Schalken, J. A., Ebeling, S. B., Issacs, J. T., Treiger, B., Bussemaker, M., and de Jong, M. E. M. Down modulation of fibronectin messenger RNA in metastasizing rat prostatic cancer cells revealed by differential hybridization analysis. Cancer Res., 48: 2042-2046, 1988.
12. Urano, M., Kuroda, M., Reynolds, R., Oberley, T. D., and St. Clair, D. K. Expression of manganese superoxide dismutase reduces tumor control radiation dose: gene radiotherapy. Cancer Res., 55: 2490-2493, 1995.
13. Fridovich, I. The biology of oxygen radicals: the superoxide radical is an agent of oxygen toxicity: superoxide dismutase provides an important defense. Science (Washington DC), 201: 875-880, 1978.
14. Cerutti, P. A. Prooxidant states and tumor promotion. Science (Washington DC), 227: 375-381, 1985.
15. Sun, Y., and Oberley, L. W. Redox regulation of transcriptional activators. Free Radical Biol. Med., 21: 335-348, 1996.
16. Majima, H., Urano, M., Sougawa, M., Kahn, J. Radiation and thermal sensitivities of murine tumor (FSa-II) cells recurrent after a heavy irradiation. Int. J. Radiat. Oncol. Biol. Phys., 22: 1019-1028, 1992.
17. Oberley, L. W., St. Clair, D. K., Autor, A. P., and Oberley, T. D. Increase in manganese superoxide dismutase activity in the mouse heart after x-irradiation. Arch. Biochem. Biophys. 254: 69-80, 1987.
18. Dignam, J, D., and Roeder, R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res., 11: 1475-1489, 1983.
19. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Ritter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18: 5294-5299, 1979.
20. Graham, F. L., and Van Der Eb, A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology, 52: 456-467, 1973.
21. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
22. Gunning, P., Muscat, G., Ng, S., and Kedes, L. A human β-actin expression vector system directs high-level accumulation of antisense transcripts. Proc. Natl. Acad. Sci. USA, 84: 4831-4835, 1987.
23. Angel, P., and Karin, M. The role of jun, fos and the AP-1 complex in cellproliferation and transformation. Biochim. Biophys. Acta, 1072: 129-157, 1991.
24. Irani, K., Xia, Y., Zweier, J. L., Sollott, S. J., Der, C. J., Fearon, E. R., Sundaresan, M., Finkel, T., and Coldschmidt-Clermont, P. J. Mitogenic signaling mediated by oxidants in ras-transformed fibroblasts. Science (Washington DC), 275: 1649-1652, 1997.
25. Amstad, P. A., Krupitza, G., and Cerutti, P. A. Mechanism of c-fos induction by active oxygen. Cancer Res., 52: 3952-3960, 1992.
26. 2 is directly related to increased proliferation and transformation of tracheal epithelial cells. Cancer Res., 55: 2723-2726, 1995.
27. Abate, C., Patel, L, Rauscher, F. J., and Curran, T. Redox regulation of fos and jun DNA-binding activity in vitro. Science (Washington DC), 249: 1157-1161, 1990.
28. Macgregor, P. F., Abate, C., and Curran, T. Direct cloning of leucine zipper proteins: jun binds cooperatively to the CRE with CRE-BP1. Oncogene, 5: 451-458, 1990.
29. Benbrook, D. M., and Jones, N. C. Heterodimer formation between CREB and JUN proteins. Oncogene, 5: 295-302, 1990.
30. Guy, G. R., Cairns, J., Ng, S. B., and Tan, Y. H. Inactivation of a redox-sensitive protein phosphatase during the early events of tumor necrosis factor/interleukin-1 signal transduction. J. Biol. Chem., 268: 2141-2148, 1993.
31. Bauskin, A. R., Alakalay, I., and Ben-Neriah, Y. Redox regulation of a protein tyrosine kinase in the endoplasmic reticulum. Cell, 66: 685-696, 1991.
32. Monteiro, H. P., and Stern, A. Redox modulation of tyrosine phosphorylation-dependent signal transduction pathways. Free Radical Biol. Med., 21: 323-333, 1996.
33. Bergelson, S., Pinkus, R., and Daniel, V. Intracellular glutathione levels regulate fos/jun induction and activation of glutathione S-transferase gene expression. Cancer Res., 54: 36-40, 1994.
34. Yoshioka, K., Deng, T., Cavigelli, M., and Karin, M. Antitumor promotion by phenolic antioxidants: inhibition of AP-1 activity through induction of fra expression. Proc. Natl. Acad. Sci. USA, 92: 4972-4976, 1995.
35. Grillot, D. A. M., Gonzalez-Garcia, M., Ekhterae, D., Duan, L., Inohara, N., Ohta, S., Seldin, M. F., and Nunez, G. Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene. J. Immunol., 158: 4750-4757, 1997.
36. Gonzalez-Garcia, M., Perez-Ballestero, R., Ding, L., Duan, L., Boise, L. H., Thompson, C. B., and Nunez, G. bcl-xL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development (Camb.), 120: 3033-3042, 1994.
37. Boise, L. H., Gonzalez-Garcia, M., Postema, C. E., Ding, L., Lindsten, T., Turka, L. A., Mao, X., Nunez, G., and Thompson, C. B. bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell, 74: 597-608, 1993.
38. Tsujimoto, Y., and Croce, C. M. Involvement of the bcl-2 gene in human follicular lymphoma. Science (Washington DC), 228: 1440-1443, 1985.
39. Kuhl, J. S., Krajewski, S., Duan, G. E., Reed, J. C. and Sikic, B. I. Spontaneous overexpression of the long form of the Bcl-x protein in a highly resistant P388 leukaemia. Br. J. Cancer, 75: 268-274, 1997.
40. McDonnell, T. J., Deane, N., Platt, F. M., Nunez, G., Jaeger, U., McKearn, J. P., and Korsmeyer, S. J. bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell, 57: 79-88, 1989.
41. L by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation. Cell Growth Differ., 6: 363-370, 1995.