Characterization of stem cells and cancer cells on the basis of gene expression profile stability, plasticity, and robustness: Dynamical systems theory of gene expressions under cell-cell interaction explains mutational robustness of differentiated cells and suggests how cancer cells emerge

BioEssays

Volumn 33, Issue 6, 2011, Pages 403-413

  Kaneko, Kunihiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Attractor; Cell cell interaction; Evolution; Robustness; Stem cell

Indexed keywords

ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL INTERACTION; GENE CONTROL; GENE EXPRESSION PROFILING; GENE MUTATION; HUMAN; NONHUMAN; STEM CELL;

BIOLOGICAL EVOLUTION; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; GENOMIC INSTABILITY; HOMEOSTASIS; HUMANS; MODELS, GENETIC; MUTATION; NEOPLASMS; PHENOTYPE; STEM CELLS;

EID: 79956132200     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201000153     Document Type: Article

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