-
1
-
-
55849083978
-
Rit signaling contributes to interferon-gamma-induced dendritic retraction via p38 mitogen-activated protein kinase activation
-
Andres, D. A., G. X. Shi, D. Bruun, C. Barnhart, and P. J. Lein. 2008. Rit signaling contributes to interferon-gamma-induced dendritic retraction via p38 mitogen-activated protein kinase activation. J. Neurochem. 107:1436-1447.
-
(2008)
J. Neurochem.
, vol.107
, pp. 1436-1447
-
-
Andres, D.A.1
Shi, G.X.2
Bruun, D.3
Barnhart, C.4
Lein, P.J.5
-
2
-
-
2342667386
-
Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins
-
Arthur, J. S., et al. 2004. Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins. J. Neurosci. 24:4324-4332.
-
(2004)
J. Neurosci.
, vol.24
, pp. 4324-4332
-
-
Arthur, J.S.1
-
3
-
-
3242879188
-
The stress of dying: the role of heat shock proteins in the regulation of apoptosis
-
Beere, H. M. 2004. "The stress of dying": the role of heat shock proteins in the regulation of apoptosis. J. Cell Sci. 117:2641-2651.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 2641-2651
-
-
Beere, H.M.1
-
4
-
-
42949165854
-
PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival
-
Bozulic, L., B. Surucu, D. Hynx, and B. A. Hemmings. 2008. PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival. Mol. Cell 30:203-213.
-
(2008)
Mol. Cell
, vol.30
, pp. 203-213
-
-
Bozulic, L.1
Surucu, B.2
Hynx, D.3
Hemmings, B.A.4
-
5
-
-
16644370412
-
Human RAS superfamily proteins and related GTPases
-
Colicelli, J. 2004. Human RAS superfamily proteins and related GTPases. Sci. STKE 2004:RE13.
-
(2004)
Sci. STKE
, vol.2004
-
-
Colicelli, J.1
-
6
-
-
27744522930
-
Potential adverse effects associated with inhibition of p38alpha/beta MAP kinases
-
Dambach, D. M. 2005. Potential adverse effects associated with inhibition of p38alpha/beta MAP kinases. Curr. Top. Med. Chem. 5:929-939.
-
(2005)
Curr. Top. Med. Chem.
, vol.5
, pp. 929-939
-
-
Dambach, D.M.1
-
7
-
-
23044467856
-
PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle
-
Dong, L. Q., and F. Liu. 2005. PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle. Am. J. Physiol. Endocrinol. Metab. 289:E187-E196.
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
-
-
Dong, L.Q.1
Liu, F.2
-
8
-
-
33746257209
-
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
-
Engelman, J. A., J. Luo, and L. C. Cantley. 2006. The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism. Nat. Rev. Genet. 7:606-619.
-
(2006)
Nat. Rev. Genet.
, vol.7
, pp. 606-619
-
-
Engelman, J.A.1
Luo, J.2
Cantley, L.C.3
-
9
-
-
33244471768
-
MAPKAP kinases-MKs-two's company, three's a crowd
-
Gaestel, M. 2006. MAPKAP kinases-MKs-two's company, three's a crowd. Nat. Rev. Mol. Cell Biol. 7:120-130.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 120-130
-
-
Gaestel, M.1
-
10
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito, K., et al. 2006. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat. Med. 12:446-451.
-
(2006)
Nat. Med.
, vol.12
, pp. 446-451
-
-
Ito, K.1
-
11
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto, E., et al. 2006. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 127:125-137.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
-
12
-
-
0027391629
-
Small heat shock proteins are molecular chaperones
-
Jakob, U., M. Gaestel, K. Engel, and J. Buchner. 1993. Small heat shock proteins are molecular chaperones. J. Biol. Chem. 268:1517-1520.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1517-1520
-
-
Jakob, U.1
Gaestel, M.2
Engel, K.3
Buchner, J.4
-
13
-
-
0033602364
-
Nervegrowth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells
-
Klesse, L. J., K. A. Meyers, C. J. Marshall, and L. F. Parada. 1999. Nervegrowth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells. Oncogene 18:2055-2068.
-
(1999)
Oncogene
, vol.18
, pp. 2055-2068
-
-
Klesse, L.J.1
Meyers, K.A.2
Marshall, C.J.3
Parada, L.F.4
-
14
-
-
70350474677
-
Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology
-
Kostenko, S., and U. Moens. 2009. Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology. Cell. Mol. Life Sci. 66:3289-3307.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 3289-3307
-
-
Kostenko, S.1
Moens, U.2
-
15
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis, J. M., and J. Avruch. 2001. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81:807-869.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
16
-
-
0033515597
-
HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus
-
Lambert, H., S. J. Charette, A. F. Bernier, A. Guimond, and J. Landry. 1999. HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus. J. Biol. Chem. 274:9378-9385.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9378-9385
-
-
Lambert, H.1
Charette, S.J.2
Bernier, A.F.3
Guimond, A.4
Landry, J.5
-
17
-
-
34247486628
-
The novel GTPase Rit differentially regulates axonal and dendritic growth
-
Lein, P. J., et al. 2007. The novel GTPase Rit differentially regulates axonal and dendritic growth. J. Neurosci. 27:4725-4736.
-
(2007)
J. Neurosci.
, vol.27
, pp. 4725-4736
-
-
Lein, P.J.1
-
18
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
-
Liu, X., C. N. Kim, J. Yang, R. Jemmerson, and X. Wang. 1996. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
19
-
-
0033595764
-
Neuronal activity-dependent cell survival mediated by transcription factor MEF2
-
Mao, Z., A. Bonni, F. Xia, M. Nadal-Vicens, and M. E. Greenberg. 1999. Neuronal activity-dependent cell survival mediated by transcription factor MEF2. Science 286:785-790.
-
(1999)
Science
, vol.286
, pp. 785-790
-
-
Mao, Z.1
Bonni, A.2
Xia, F.3
Nadal-Vicens, M.4
Greenberg, M.E.5
-
20
-
-
0344393408
-
Regulation of MAP kinase signaling modules by scaffold proteins in mammals
-
Morrison, D. K., and R. J. Davis. 2003. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu. Rev. Cell Dev. Biol. 19: 91-118.
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 91-118
-
-
Morrison, D.K.1
Davis, R.J.2
-
21
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
-
Pearson, G., et al. 2001. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 22:153-183.
-
(2001)
Endocr. Rev.
, vol.22
, pp. 153-183
-
-
Pearson, G.1
-
22
-
-
0035793574
-
p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils
-
Rane, M. J., et al. 2001. p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils. J. Biol. Chem. 276:3517-3523.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3517-3523
-
-
Rane, M.J.1
-
23
-
-
0041344614
-
Heat shock protein 27 controls apoptosis by regulating Akt activation
-
Rane, M. J., et al. 2003. Heat shock protein 27 controls apoptosis by regulating Akt activation. J. Biol. Chem. 278:27828-27835.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27828-27835
-
-
Rane, M.J.1
-
24
-
-
0033516660
-
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation
-
Rogalla, T., et al. 1999. Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. J. Biol. Chem. 274:18947-18956.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18947-18956
-
-
Rogalla, T.1
-
25
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov, D. D., D. A. Guertin, S. M. Ali, and D. M. Sabatini. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
26
-
-
0033373475
-
HSP27 expression regulates CCK-induced changes of the actin cytoskeleton in CHO-CCK-A cells
-
Schafer, C., P. Clapp, M. J. Welsh, R. Benndorf, and J. A. Williams. 1999. HSP27 expression regulates CCK-induced changes of the actin cytoskeleton in CHO-CCK-A cells. Am. J. Physiol. 277:C1032-C1043.
-
(1999)
Am. J. Physiol.
, vol.277
-
-
Schafer, C.1
Clapp, P.2
Welsh, M.J.3
Benndorf, R.4
Williams, J.A.5
-
27
-
-
11844254750
-
Rit contributes to nerve growth factorinduced neuronal differentiation via activation of B-Raf-extracellular signalregulated kinase and p38 mitogen-activated protein kinase cascades
-
Shi, G. X., and D. A. Andres. 2005. Rit contributes to nerve growth factorinduced neuronal differentiation via activation of B-Raf-extracellular signalregulated kinase and p38 mitogen-activated protein kinase cascades. Mol. Cell. Biol. 25:830-846.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 830-846
-
-
Shi, G.X.1
Andres, D.A.2
-
28
-
-
49449087527
-
Pituitary adenylate cyclaseactivating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation
-
Shi, G. X., L. Jin, and D. A. Andres. 2008. Pituitary adenylate cyclaseactivating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation. Mol. Cell. Biol. 28:4940-4951.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4940-4951
-
-
Shi, G.X.1
Jin, L.2
Andres, D.A.3
-
29
-
-
33845194359
-
A novel cyclic AMPdependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation
-
Shi, G. X., H. Rehmann, and D. A. Andres. 2006. A novel cyclic AMPdependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation. Mol. Cell. Biol. 26:9136-9147.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 9136-9147
-
-
Shi, G.X.1
Rehmann, H.2
Andres, D.A.3
-
30
-
-
0037036467
-
Induction of neurite extension and survival in pheochromocytoma cells by the Rit GTPase
-
Spencer, M. L., H. Shao, and D. A. Andres. 2002. Induction of neurite extension and survival in pheochromocytoma cells by the Rit GTPase. J. Biol. Chem. 277:20160-20168.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 20160-20168
-
-
Spencer, M.L.1
Shao, H.2
Andres, D.A.3
-
31
-
-
70350537407
-
HSP27: mechanisms of cellular protection against neuronal injury
-
Stetler, R. A., Y. Gao, A. P. Signore, G. Cao, and J. Chen. 2009. HSP27: mechanisms of cellular protection against neuronal injury. Curr. Mol. Med. 9:863-872.
-
(2009)
Curr. Mol. Med.
, vol.9
, pp. 863-872
-
-
Stetler, R.A.1
Gao, Y.2
Signore, A.P.3
Cao, G.4
Chen, J.5
-
32
-
-
0026653977
-
Small GTPbinding proteins
-
Takai, Y., K. Kaibuchi, A. Kikuchi, and M. Kawata. 1992. Small GTPbinding proteins. Int. Rev. Cytol. 133:187-230.
-
(1992)
Int. Rev. Cytol.
, vol.133
, pp. 187-230
-
-
Takai, Y.1
Kaibuchi, K.2
Kikuchi, A.3
Kawata, M.4
-
33
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADPribose) polymerase
-
Tewari, M., et al. 1995. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADPribose) polymerase. Cell 81:801-809.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
-
34
-
-
43249106330
-
Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation
-
Thornton, T. M., et al. 2008. Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation. Science 320:667-670.
-
(2008)
Science
, vol.320
, pp. 667-670
-
-
Thornton, T.M.1
-
35
-
-
60149093582
-
Non-classical p38 map kinase functions: cell cycle checkpoints and survival
-
Thornton, T. M., and M. Rincon. 2009. Non-classical p38 map kinase functions: cell cycle checkpoints and survival. Int. J. Biol. Sci. 5:44-51.
-
(2009)
Int. J. Biol. Sci.
, vol.5
, pp. 44-51
-
-
Thornton, T.M.1
Rincon, M.2
-
36
-
-
48149114500
-
Akt signaling: a damaging interaction makes good
-
Toker, A. 2008. Akt signaling: a damaging interaction makes good. Trends Biochem. Sci. 33:356-359.
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 356-359
-
-
Toker, A.1
-
37
-
-
0344668554
-
Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock
-
Uhlik, M. T., et al. 2003. Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. Nat. Cell Biol. 5:1104-1110.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 1104-1110
-
-
Uhlik, M.T.1
-
38
-
-
0034653608
-
The PI3K-PDK1 connection: more than just a road to PKB
-
Vanhaesebroeck, B., and D. R. Alessi. 2000. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346(3):561-576.
-
(2000)
Biochem. J.
, vol.346
, Issue.3
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
39
-
-
67749117934
-
Signal integration by JNK and p38 MAPK pathways in cancer development
-
Wagner, E. F., and A. R. Nebreda. 2009. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 9:537-549.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 537-549
-
-
Wagner, E.F.1
Nebreda, A.R.2
-
40
-
-
34547588567
-
Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex
-
Wu, R., et al. 2007. Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex. J. Biol. Chem. 282:21598-21608.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 21598-21608
-
-
Wu, R.1
-
41
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia, Z., M. Dickens, J. Raingeaud, R. J. Davis, and M. E. Greenberg. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
42
-
-
33846000629
-
MAPK-activated protein kinase 2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27
-
Zheng, C., et al. 2006. MAPK-activated protein kinase 2 (MK2)-mediated formation and phosphorylation-regulated dissociation of the signal complex consisting of p38, MK2, Akt, and Hsp27. J. Biol. Chem. 281:37215-37226.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 37215-37226
-
-
Zheng, C.1
|