메뉴 건너뛰기




Volumn 31, Issue 4, 2011, Pages 1345-1357

Differential apoptotic effects of novel quinuclidinone analogs 8a and 8b in normal and lung cancer cell lines

Author keywords

Anticancer agents; Apoptosis; Caspase 3; Cell cycle; Cox 2; p53; Sphingomylinase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; CASPASE 3; CISPLATIN; CYCLIN B; CYCLOOXYGENASE 2; DNA NUCLEOTIDYLEXOTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN P53; QUINUCLIDINE DERIVATIVE; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 79956125266     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (45)
  • 1
    • 0035525733 scopus 로고    scopus 로고
    • Cellular stress response and apoptosis in cancer therapy
    • Herr I and Debatin KM: Cellular stress response and apoptosis in cancer therapy. Blood 98: 2603-2614, 2001.
    • (2001) Blood , vol.98 , pp. 2603-2614
    • Herr, I.1    Debatin, K.M.2
  • 2
    • 0034630167 scopus 로고    scopus 로고
    • Induction of apoptosis by cancer chemotherapy
    • Kaufmann SH and Earnshaw WC: Induction of apoptosis by cancer chemotherapy. Exp Cell Res 256: 42-49, 2000.
    • (2000) Exp Cell Res , vol.256 , pp. 42-49
    • Kaufmann, S.H.1    Earnshaw, W.C.2
  • 3
    • 31344468628 scopus 로고    scopus 로고
    • Structure-activity studies of quinuclidinone analogs as anti-proliferative agents in lung cancer cell lines
    • DOI 10.1016/j.bmcl.2005.11.085, PII S0960894X05015131
    • Malki A, Pulipaka A, Susan S and Bergmeier S: Structure activity studies of quinuclidinone analogs as antiproliferative agents in lung cancer cell lines. Bioorg Med Chem Lett 16: 1156-1159, 2006. (Pubitemid 43142982)
    • (2006) Bioorganic and Medicinal Chemistry Letters , vol.16 , Issue.5 , pp. 1156-1159
    • Malki, A.1    Pulipaka, A.B.2    Evans, S.C.3    Bergmeier, S.C.4
  • 4
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA-damaging agents and growth arrest
    • Zhan Q, Carrier F and Fornace AJ: Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol 13: 4242-4250, 1993. (Pubitemid 23187653)
    • (1993) Molecular and Cellular Biology , vol.13 , Issue.7 , pp. 4242-4250
    • Zhan, Q.1    Carrier, F.2    Fornace Jr., A.J.3
  • 5
    • 0028901034 scopus 로고
    • Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
    • Fan S, Smith ML and Rivet DJ: Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 55: 1649-1654, 1995.
    • (1995) Cancer Res , vol.55 , pp. 1649-1654
    • Fan, S.1    Smith, M.L.2    Rivet, D.J.3
  • 6
    • 0030021996 scopus 로고    scopus 로고
    • Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
    • Hawkins DS, Demers GW and Galloway DA: Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res 56: 892-898, 1996. (Pubitemid 26055483)
    • (1996) Cancer Research , vol.56 , Issue.4 , pp. 892-898
    • Hawkins, D.S.1    Demers, G.W.2    Galloway, D.A.3
  • 7
    • 79956089417 scopus 로고    scopus 로고
    • Differential effect of selected methylxanthine derivatives on radiosensitization and cell cycle of normal and lung cancer cell lines
    • Malki A and Susan S: Differential effect of selected methylxanthine derivatives on radiosensitization and cell cycle of normal and lung cancer cell lines. Exp Oncol 28(1): 18-24, 2006.
    • (2006) Exp Oncol , vol.28 , Issue.1 , pp. 18-24
    • Malki, A.1    Susan, S.2
  • 8
    • 0031263872 scopus 로고    scopus 로고
    • A recombinant adenovirus expressing wild type p53 induces apoptosis in drug-resistant human breast cancer cells: A gene therapy approach for drug-resistant cancers
    • Seth P, Katayose D, Li Z, Kim, M., Wersto R, Craig C, Shanmugam N, Ohri E, Mudahar B, Rakkar AN, Kodali P and Cowan K: A recombinant adenovirus expressing wild-type p53 induces apoptosis in drag-resistant human breast cancer cells: a gene therapy approach for drug-resistant cancers. Cancer Gene Ther 4: 383-390, 1997. (Pubitemid 127667131)
    • (1997) Cancer Gene Therapy , vol.4 , Issue.6 , pp. 383-390
    • Seth, P.1    Katayose, D.2    Li, Z.3    Kim, M.4    Wersto, R.5    Craig, C.6    Shanmugam, N.7    Ohri, E.8    Mudahar, B.9    Rakkar, A.N.S.10    Kodali, P.11    Cowan, K.12
  • 10
    • 0029962567 scopus 로고    scopus 로고
    • Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells
    • Yang B, Eshleman JR, Berger NA and Markowitz SD: Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells. Clinical Cancer Res 2: 1649-1657, 1996. (Pubitemid 26356347)
    • (1996) Clinical Cancer Research , vol.2 , Issue.10 , pp. 1649-1657
    • Yang, B.1    Eshleman, J.R.2    Berger, N.A.3    Markowitz, S.D.4
  • 11
    • 0035883628 scopus 로고    scopus 로고
    • Wild-type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down-regulating multidrug resistance-1 expression
    • Zhan M, Yu D, Lang A, Li L and Pollock RE: Wild-type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down-regulating multidrug resistance-1 expression. Cancer 92: 1556-1566, 2001.
    • (2001) Cancer , vol.92 , pp. 1556-1566
    • Zhan, M.1    Yu, D.2    Lang, A.3    Li, L.4    Pollock, R.E.5
  • 12
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D and Weinberg RA: The hallmarks of cancer. Cell 100: 57-70, 2000. (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 13
    • 0028265959 scopus 로고
    • Lipid second messengers
    • DOI 10.1016/0092-8674(94)90148-1
    • Liscovitch M and Cantley LC: Lipid second messengers. Cell 77: 329-334, 1994. (Pubitemid 24145194)
    • (1994) Cell , vol.77 , Issue.3 , pp. 329-334
    • Liscovitch, M.1    Cantley, L.C.2
  • 14
    • 58149277751 scopus 로고    scopus 로고
    • Roles of bioactive sphingolipids in cancer biology and therapeutics
    • Saddoughi SA, Song P and Ogretmen B: Roles of bioactive sphingolipids in cancer biology and therapeutics. Subcell Biochem 49: 413-440, 2008.
    • (2008) Subcell Biochem , vol.49 , pp. 413-440
    • Saddoughi, S.A.1    Song, P.2    Ogretmen, B.3
  • 15
    • 0030634437 scopus 로고    scopus 로고
    • Ceramide a novel lipid mediator of apoptosis
    • Smyth ML, Obeid LM and Hannun YA: Ceramide a novel lipid mediator of apoptosis. Adv Pharmacol 41: 133-154, 1997.
    • (1997) Adv Pharmacol , vol.41 , pp. 133-154
    • Smyth, M.L.1    Obeid, L.M.2    Hannun, Y.A.3
  • 16
    • 77951922837 scopus 로고    scopus 로고
    • Fine tuning of cell functions through remodeling of glycosphingolipids by plasma membrane-associated glycohydrolases
    • Sonnino S, Aureli M, Loberto N, Chigorno V and Prinetti A: Fine tuning of cell functions through remodeling of glycosphingolipids by plasma membrane-associated glycohydrolases. FEBS Lett 584: 1914-1922, 2010.
    • (2010) FEBS Lett , vol.584 , pp. 1914-1922
    • Sonnino, S.1    Aureli, M.2    Loberto, N.3    Chigorno, V.4    Prinetti, A.5
  • 18
    • 0033786639 scopus 로고    scopus 로고
    • Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy
    • Morita Y, Perez GI and Paris F: Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy. Nat Med 6(10): 1109-1114, 2000.
    • (2000) Nat Med , vol.6 , Issue.10 , pp. 1109-1114
    • Morita, Y.1    Perez, G.I.2    Paris, F.3
  • 21
    • 0034900406 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 in squamous cell carcinoma of the urinary bladder
    • Shirahama T and Sakakura C: Overexpression of cyclooxygenase-2 in squamous cell carcinoma of the urinary bladder. Clin Cancer Res 7: 558-561, 2001. (Pubitemid 32707978)
    • (2001) Clinical Cancer Research , vol.7 , Issue.3 , pp. 558-561
    • Shirahama, T.1    Sakakura, C.2
  • 23
    • 0027993458 scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
    • Eberhat CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S and DuBois RN: Up-regulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107: 1183-1188, 1994. (Pubitemid 24294584)
    • (1994) Gastroenterology , vol.107 , Issue.4 , pp. 1183-1188
    • Eberhart, C.E.1    Coffey, R.J.2    Radhika, A.3    Giardiello, F.M.4    Ferrenbach, S.5    DuBois, R.N.6
  • 24
    • 0034650771 scopus 로고    scopus 로고
    • Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis
    • Reddy BS, Hirose Y and Lubet R: Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. Cancer Res 60: 293-297, 2000. (Pubitemid 30070754)
    • (2000) Cancer Research , vol.60 , Issue.2 , pp. 293-297
    • Reddy, B.S.1    Hirose, Y.2    Lubet, R.3    Steele, V.4    Kelloff, G.5    Paulson, S.6    Seibert, K.7    Rao, C.V.8
  • 25
    • 0033591794 scopus 로고    scopus 로고
    • Early trials probe COX-2 inhibitors' cancer-fighting potential
    • Ziegler J: Early trials probe COX-2 inhibitors' cancer-fighting potential. J Natl Cancer Inst 91: 1186-1187, 1999.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1186-1187
    • Ziegler, J.1
  • 26
    • 24644523517 scopus 로고    scopus 로고
    • The role of caspases in cell death and differentiation
    • DOI 10.1016/j.drup.2005.05.001, PII S1368764605000440
    • Oliver L and Vallette FM: The role of caspases in cell death and differentiation. Drag Resist Updat 8(3): 163-170, 2005. (Pubitemid 41267066)
    • (2005) Drug Resistance Updates , vol.8 , Issue.3 , pp. 163-170
    • Oliver, L.1    Vallette, F.M.2
  • 27
    • 0242432345 scopus 로고    scopus 로고
    • Many cuts to rain: A comprehensive update of caspase substrates
    • Fischer U, Janicke RU and Schulze-Osthoff K: Many cuts to rain: a comprehensive update of caspase substrates. Cell Death Differ 10(1): 76-100, 2003.
    • (2003) Cell Death Differ , vol.10 , Issue.1 , pp. 76-100
    • Fischer, U.1    Janicke, R.U.2    Schulze-Osthoff, K.3
  • 28
    • 0037252734 scopus 로고    scopus 로고
    • Epidemiology of lung cancer
    • Alberg AJ and Samet JM: Epidemiology of lung cancer. Chest J 123(1 Suppl): 21S-49S, 2003.
    • (2003) Chest J , vol.123 , Issue.1 SUPPL.
    • Alberg, A.J.1    Samet, J.M.2
  • 29
    • 2442543093 scopus 로고    scopus 로고
    • Genetic predisposition to lung cancer
    • Schwartz AG: genetic predisposition to lung cancer. Chest 125(5 Suppl): 86S-89S, 2004.
    • (2004) Chest , vol.125 , Issue.5 SUPPL.
    • Schwartz, A.G.1
  • 30
    • 0032011418 scopus 로고    scopus 로고
    • Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cells
    • Adachi H, Preston G, Harvat B, Dawson MI and Jetten AM: Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cells. Am J Respir Cell Mol Biol 18(3): 323-233, 1998.
    • (1998) Am J Respir Cell Mol Biol , vol.18 , Issue.3 , pp. 323-1233
    • Adachi, H.1    Preston, G.2    Harvat, B.3    Dawson, M.I.4    Jetten, A.M.5
  • 31
    • 0027970713 scopus 로고
    • 1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • 1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes Dev 8(21): 2540-2551, 1994. (Pubitemid 24347245)
    • (1994) Genes and Development , vol.8 , Issue.21 , pp. 2540-2551
    • Di, L.A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 33
    • 0037108873 scopus 로고    scopus 로고
    • 2-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1
    • Yu Q, La Rose J, Zhang H, Takemura H, Kohn KW and Pommier Y: UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1. Cancer Res 62: 5743-5748, 2002. (Pubitemid 35204730)
    • (2002) Cancer Research , vol.62 , Issue.20 , pp. 5743-5748
    • Yu, Q.1    La, R.J.2    Zhang, H.3    Takemura, H.4    Kohn, K.W.5    Pommier, Y.6
  • 34
    • 0032126541 scopus 로고    scopus 로고
    • Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines
    • Aldridge DR and Radford IR: Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines. Cancer Res 58: 2817-2824, 1998. (Pubitemid 28311913)
    • (1998) Cancer Research , vol.58 , Issue.13 , pp. 2817-2824
    • Aldridge, D.R.1    Radford, I.R.2
  • 36
    • 1842600898 scopus 로고
    • Animal cell cycles and their control
    • Nobury C and Nurse P: Animal cell cycles and their control. Trends Biochem Sci 19: 143-145, 1992.
    • (1992) Trends Biochem Sci , vol.19 , pp. 143-145
    • Nobury, C.1    Nurse, P.2
  • 38
    • 0028855405 scopus 로고
    • Ceramide: An intracellular signal for apoptosis
    • Hannun YA and Obeid LM: Ceramide: an intracellular signal for apoptosis. Trends Biochem Sci 20(2): 73-77, 1995.
    • (1995) Trends Biochem Sci , vol.20 , Issue.2 , pp. 73-77
    • Hannun, Y.A.1    Obeid, L.M.2
  • 40
    • 3042836326 scopus 로고    scopus 로고
    • COX-2 inhibition and lung cancer
    • Sandler AB and Dubinett SM: COX-2 inhibition and lung cancer. Semin Oncol 31(2): 45-52, 2004.
    • (2004) Semin Oncol , vol.31 , Issue.2 , pp. 45-52
    • Sandler, A.B.1    Dubinett, S.M.2
  • 41
    • 0030589376 scopus 로고    scopus 로고
    • 2 Enhance Peripheral Blood Lymphocyte IL-10 Transcription and Protein Production
    • 2 enhance peripheral blood lymphocyte IL-10 transcription and protein production. J Immunol 157: 5512-5520, 1996. (Pubitemid 126448972)
    • (1996) Journal of Immunology , vol.157 , Issue.12 , pp. 5512-5520
    • Huang, M.1    Sharma, S.2    Mao, J.T.3    Dubinett, S.M.4
  • 43
    • 12144291145 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines, ENA-78/CXCL5 and IL-8/CXCL8, in human non-small cell lung cancer
    • Põld M, Zhu LX, Sharma S, Burdek, M, Lin Y, Pold A, Krysan A, Moa J, Batra R, Strieter, R and Dubinet S: Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines, ENA-78/CXCL5 and IL-8/CXCL8, in human non-small cell lung cancer. Cancer Res 64: 1853-1860, 2004.
    • (2004) Cancer Res , vol.64 , pp. 1853-1860
    • Põld, M.1    Zhu, L.X.2    Sharma, S.3    Burdek, M.4    Lin, Y.5    Pold, A.6    Krysan, A.7    Moa, J.8    Batra, R.9    Strieter, R.10    Dubinet, S.11
  • 45
    • 0036716281 scopus 로고    scopus 로고
    • The BCL2 family: Regulators of the cellular life-or-death switch
    • DOI 10.1038/nrc883
    • Cory S and Adams JM: The Bcl2 family: regulators of the cellular life or death switch. Nat Rev Cancer 2: 647-656, 2002. (Pubitemid 37328916)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.9 , pp. 647-656
    • Cory, S.1    Adams, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.