메뉴 건너뛰기




Volumn 85, Issue 11, 1998, Pages 1460-1467

The p53 tumour suppressor gene

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 0031726889     PISSN: 00071323     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2168.1998.00910.x     Document Type: Article
Times cited : (190)

References (87)
  • 2
    • 0017250977 scopus 로고
    • DNA related to the transforming gene(s) of avian sarcoma virus is present in normal avian DNA
    • Stehelin D, Varmus HE, Bishop JM, Vogt PK. DNA related to the transforming gene(s) of avian sarcoma virus is present in normal avian DNA. Nature 1976; 260: 170-3.
    • (1976) Nature , vol.260 , pp. 170-173
    • Stehelin, D.1    Varmus, H.E.2    Bishop, J.M.3    Vogt, P.K.4
  • 3
    • 0018077621 scopus 로고
    • Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates
    • Spector DH, Varmus HE, Bishop JM. Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. Proc Natl Acad Sci USA 1978; 75: 4102-6.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 4102-4106
    • Spector, D.H.1    Varmus, H.E.2    Bishop, J.M.3
  • 4
    • 0028174024 scopus 로고
    • A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma
    • Hofstra RMW, Landsvater RM, Ceccherini I, Stulp RP, Stelwagen T, Luo Y et al. A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma. Nature 1994; 367: 375-6.
    • (1994) Nature , vol.367 , pp. 375-376
    • Hofstra, R.M.W.1    Landsvater, R.M.2    Ceccherini, I.3    Stulp, R.P.4    Stelwagen, T.5    Luo, Y.6
  • 5
    • 0018348655 scopus 로고
    • T antigen is bound to a host protein in SV40-transformed cells
    • Lane DP, Crawford LV. T antigen is bound to a host protein in SV40-transformed cells. Nature 1979; 278: 261-3.
    • (1979) Nature , vol.278 , pp. 261-263
    • Lane, D.P.1    Crawford, L.V.2
  • 6
    • 0018760324 scopus 로고
    • Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
    • Linzer DI, Levine AJ. Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 1979; 17: 43-52.
    • (1979) Cell , vol.17 , pp. 43-52
    • Linzer, D.I.1    Levine, A.J.2
  • 7
    • 0030237476 scopus 로고    scopus 로고
    • p53-integrating the complexity
    • Editorial
    • Hall PA, Meek D, Lane DP. p53-integrating the complexity. J Pathol 1996, 180: 1-5 (Editorial).
    • (1996) J Pathol , vol.180 , pp. 1-5
    • Hall, P.A.1    Meek, D.2    Lane, D.P.3
  • 8
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997; 88: 323-31.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 12
    • 0029874308 scopus 로고    scopus 로고
    • p53-dependent apoptosis suppresses radiation-induced teratogenesis
    • Norimura T, Nomoto S, Katsuki M, Gondo Y, Kondo S. p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nature Med 1996; 2: 577-80.
    • (1996) Nature Med , vol.2 , pp. 577-580
    • Norimura, T.1    Nomoto, S.2    Katsuki, M.3    Gondo, Y.4    Kondo, S.5
  • 13
    • 0030951637 scopus 로고    scopus 로고
    • Tumor suppressors: A developing role for p53?
    • Hall PA, Lane DP. Tumor suppressors: a developing role for p53? Curr Biol 1997; 7: 144-7.
    • (1997) Curr Biol , vol.7 , pp. 144-147
    • Hall, P.A.1    Lane, D.P.2
  • 17
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 1992; 69: 1237-45.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 18
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997; 387: 296-9.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 19
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • Kubbutat MH, Jones SN, Vousden KH. Regulation of p53 stability by Mdm2. Nature 1997; 387: 299-303.
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 20
    • 0027244853 scopus 로고
    • The p53-mdm2 autoregulatory feedback loop
    • Wu X, Bayle JH, Olson D, Levine AJ. The p53-mdm2 autoregulatory feedback loop. Genes Dev 1993; 7: 1126-32.
    • (1993) Genes Dev , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.3    Levine, A.J.4
  • 21
    • 0028823020 scopus 로고
    • Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
    • Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 1995; 378: 203-6.
    • (1995) Nature , vol.378 , pp. 203-206
    • Montes De Oca Luna, R.1    Wagner, D.S.2    Lozano, G.3
  • 22
    • 0030612360 scopus 로고    scopus 로고
    • MDM2-arbiter of p53's destruction
    • Lane DP, Hall PA. MDM2-arbiter of p53's destruction. Trends Biochem Sci 1997; 22: 372-4.
    • (1997) Trends Biochem Sci , vol.22 , pp. 372-374
    • Lane, D.P.1    Hall, P.A.2
  • 23
    • 0030665146 scopus 로고    scopus 로고
    • Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53
    • Mayo LD, Turchi JJ, Berberich SJ. Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53. Cancer Res 1997; 57: 5013-16.
    • (1997) Cancer Res , vol.57 , pp. 5013-5016
    • Mayo, L.D.1    Turchi, J.J.2    Berberich, S.J.3
  • 25
    • 0005426877 scopus 로고
    • P53, p21WAF1/CIP1 and the control of cell proliferation
    • Thomas T, ed. London: Bios Scientific
    • El-Deiry WS. P53, p21WAF1/CIP1 and the control of cell proliferation. In: Thomas T, ed. Cell Cycle Control and Apoptosis in Malignant Disease. London: Bios Scientific, 1995: 19-38.
    • (1995) Cell Cycle Control and Apoptosis in Malignant Disease , pp. 19-38
    • El-Deiry, W.S.1
  • 27
    • 0031026001 scopus 로고    scopus 로고
    • Further characterisation of the p53 responsive element-identification of new candidate genes for trans-activation by p53
    • Bourdon JC, Deguin-Chambon V, Lelong JC, Dessen P, May P, Debuire B et al. Further characterisation of the p53 responsive element-identification of new candidate genes for trans-activation by p53. Oncogene 1997; 14: 85-94.
    • (1997) Oncogene , vol.14 , pp. 85-94
    • Bourdon, J.C.1    Deguin-Chambon, V.2    Lelong, J.C.3    Dessen, P.4    May, P.5    Debuire, B.6
  • 28
    • 0029028158 scopus 로고
    • A direct effect on activated human p53 on nuclear DNA replication
    • Cox LS, Hupp T, Midgley CA, Lane DP. A direct effect on activated human p53 on nuclear DNA replication. EMBO J 1995; 14: 2099-105.
    • (1995) EMBO J , vol.14 , pp. 2099-2105
    • Cox, L.S.1    Hupp, T.2    Midgley, C.A.3    Lane, D.P.4
  • 29
    • 0028070989 scopus 로고
    • p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles C, Helmberg A, Karin M. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 1994; 370: 220-3.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 30
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by trans-activation-deficient p53
    • Haupt Y, Rowan S, Shaulian E, Vousden KH, Oren M. Induction of apoptosis in HeLa cells by trans-activation-deficient p53. Genes Dev 1995; 9: 2170-83.
    • (1995) Genes Dev , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.H.4    Oren, M.5
  • 31
    • 0030884751 scopus 로고    scopus 로고
    • A novel protein with strong homology to the tumour suppressor p53
    • Schmale H, Bamberger C. A novel protein with strong homology to the tumour suppressor p53. Oncogene 1997; 15: 1363-7.
    • (1997) Oncogene , vol.15 , pp. 1363-1367
    • Schmale, H.1    Bamberger, C.2
  • 32
    • 0031564954 scopus 로고    scopus 로고
    • p73 is a human p53-related protein that can induce apoptosis
    • Jost CA, Marin MC, Kaelin WG Jr. p73 is a human p53-related protein that can induce apoptosis. Nature 1997; 389: 191-4.
    • (1997) Nature , vol.389 , pp. 191-194
    • Jost, C.A.1    Marin, M.C.2    Kaelin Jr., W.G.3
  • 33
    • 0031577734 scopus 로고    scopus 로고
    • Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53
    • Drane P, Barel M, Balbo M, Frade R. Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53. Oncogene 1997; 15: 3013-24.
    • (1997) Oncogene , vol.15 , pp. 3013-3024
    • Drane, P.1    Barel, M.2    Balbo, M.3    Frade, R.4
  • 34
    • 0031464286 scopus 로고    scopus 로고
    • p53CP, a putative p53 competing protein that specifically hinds to the consenus p53 DNA binding sites: A third member of the p53 family?
    • Bian J, Sun Yi. p53CP, a putative p53 competing protein that specifically hinds to the consenus p53 DNA binding sites: a third member of the p53 family? Proc Natl Acad Sci USA 1997; 94: 14753-8.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14753-14758
    • Bian, J.1    Yi, S.2
  • 35
  • 36
    • 0029051336 scopus 로고
    • Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo
    • Midgley CA, Owens B, Briscoe CV, Thomas DB, Lane DP, Hall PA. Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo. J Cell Sci 1995; 108: 1843-8.
    • (1995) J Cell Sci , vol.108 , pp. 1843-1848
    • Midgley, C.A.1    Owens, B.2    Briscoe, C.V.3    Thomas, D.B.4    Lane, D.P.5    Hall, P.A.6
  • 41
    • 0025633582 scopus 로고
    • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
    • Malkin D, Li FP, Strong LC, Fraumeni JF Jr, Nelson CE, Kim DH et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990; 250: 1233-8.
    • (1990) Science , vol.250 , pp. 1233-1238
    • Malkin, D.1    Li, F.P.2    Strong, L.C.3    Fraumeni Jr., J.F.4    Nelson, C.E.5    Kim, D.H.6
  • 42
    • 0025648762 scopus 로고
    • Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
    • Srivastava S, Zou ZQ, Pirollo K, Blattner W, Chang EH. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 1990; 348: 747-9.
    • (1990) Nature , vol.348 , pp. 747-749
    • Srivastava, S.1    Zou, Z.Q.2    Pirollo, K.3    Blattner, W.4    Chang, E.H.5
  • 43
    • 0028169994 scopus 로고
    • p53-dependent apoptosis suppresses tumor growth and progression in vivo
    • Symonds H, Krall L, Reminton L, Saenz Robles M, Lowe S, Kacks T et al. p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 1994; 78: 703-11.
    • (1994) Cell , vol.78 , pp. 703-711
    • Symonds, H.1    Krall, L.2    Reminton, L.3    Saenz Robles, M.4    Lowe, S.5    Kacks, T.6
  • 45
  • 46
    • 0025265724 scopus 로고
    • Increased expression of mutant forms of p53 oncogene in primary lung cancer
    • Iggo R, Gatter K, Bartek J, Lane D, Harris AL. Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet 1990; 335: 675-9.
    • (1990) Lancet , vol.335 , pp. 675-679
    • Iggo, R.1    Gatter, K.2    Bartek, J.3    Lane, D.4    Harris, A.L.5
  • 47
    • 0028299342 scopus 로고
    • p53 in tumour pathology: Can we trust immunohistochemistry? - Revisited
    • Hall PA, Lane DP. p53 in tumour pathology: can we trust immunohistochemistry? - revisited. J Pathol 1994; 172: 1-4.
    • (1994) J Pathol , vol.172 , pp. 1-4
    • Hall, P.A.1    Lane, D.P.2
  • 48
    • 0030825813 scopus 로고    scopus 로고
    • p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding
    • Midgley CA, Lane DP. p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding. Oncogene 1997; 15: 1179-89.
    • (1997) Oncogene , vol.15 , pp. 1179-1189
    • Midgley, C.A.1    Lane, D.P.2
  • 49
  • 53
    • 0028286988 scopus 로고
    • Cytoplasmic accumulation of p53 protein: An independent prognostic indicator in colorectal adenocarcinomas
    • Bosari S, Viale G, Bossi P, Maggioni M, Coggi G, Murray JJ et al. Cytoplasmic accumulation of p53 protein: an independent prognostic indicator in colorectal adenocarcinomas. J Natl Cancer Inst 1994; 86: 681-7.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 681-687
    • Bosari, S.1    Viale, G.2    Bossi, P.3    Maggioni, M.4    Coggi, G.5    Murray, J.J.6
  • 55
    • 0027137816 scopus 로고
    • Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer
    • Mitsudomi T, Oyama T, Kusano T, Osaki T, Nakanishi R, Shirakusa T. Mutations of the p53 gene as a predictor of poor prognosis in patients with non-small-cell lung cancer. J Natl Cancer Inst 1993; 85: 2018-23.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 2018-2023
    • Mitsudomi, T.1    Oyama, T.2    Kusano, T.3    Osaki, T.4    Nakanishi, R.5    Shirakusa, T.6
  • 56
  • 57
    • 0029401751 scopus 로고
    • The p53 tumour suppressor gene and tumour prognosis: Is there a relationship?
    • Dowell SP, Hall PA. The p53 tumour suppressor gene and tumour prognosis: is there a relationship? J Pathol 1995; 177: 221-4.
    • (1995) J Pathol , vol.177 , pp. 221-224
    • Dowell, S.P.1    Hall, P.A.2
  • 58
    • 0028986873 scopus 로고
    • P53 in node-negative breast carcinoma: An immuohistochemical study of epidemiologic risk factors, histologic features, and prognosis
    • Rosen PP, Lesser ML, Arroyo CD, Cranor M, Borgen P, Norton L. P53 in node-negative breast carcinoma: an immuohistochemical study of epidemiologic risk factors, histologic features, and prognosis. J Clin Oncol 1995; 13: 821-30.
    • (1995) J Clin Oncol , vol.13 , pp. 821-830
    • Rosen, P.P.1    Lesser, M.L.2    Arroyo, C.D.3    Cranor, M.4    Borgen, P.5    Norton, L.6
  • 59
    • 0031012326 scopus 로고    scopus 로고
    • p53 and Rb1 protein expression: Are they prognostically useful in colorectal cancer?
    • Poller DN, Baxter KJ, Shepherd NA. p53 and Rb1 protein expression: are they prognostically useful in colorectal cancer? Br J Cancer 1997; 75: 87-93.
    • (1997) Br J Cancer , vol.75 , pp. 87-93
    • Poller, D.N.1    Baxter, K.J.2    Shepherd, N.A.3
  • 60
    • 0028207349 scopus 로고
    • An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
    • Baas IO, Mulder JW, Offerhaus B, Vogelstein B, Hamilton SR. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994; 172: 5-12.
    • (1994) J Pathol , vol.172 , pp. 5-12
    • Baas, I.O.1    Mulder, J.W.2    Offerhaus, B.3    Vogelstein, B.4    Hamilton, S.R.5
  • 61
    • 0029966127 scopus 로고    scopus 로고
    • Potential false-positive results with antigen enhancement for immunohistochemistry of the p53 gene product in colorectal neoplasms
    • Baas IO, van den Berg FM, Mulder JW, Clement MJ, Slebos RJC, Hamilton SR et al. Potential false-positive results with antigen enhancement for immunohistochemistry of the p53 gene product in colorectal neoplasms. J Pathol 1996; 178: 264-7.
    • (1996) J Pathol , vol.178 , pp. 264-267
    • Baas, I.O.1    Van Den Berg, F.M.2    Mulder, J.W.3    Clement, M.J.4    Slebos, R.J.C.5    Hamilton, S.R.6
  • 62
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 1990; 63: 1129-36.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 63
    • 0029783722 scopus 로고    scopus 로고
    • A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
    • Friedlander P, Haupt Y, Prives C, Oren M. A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol Cell Biol 1996; 16: 4961-71.
    • (1996) Mol Cell Biol , vol.16 , pp. 4961-4971
    • Friedlander, P.1    Haupt, Y.2    Prives, C.3    Oren, M.4
  • 64
  • 66
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993; 74: 957-68.
    • (1993) Cell , vol.74 , pp. 957-968
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 67
    • 0027285380 scopus 로고
    • p53 mutations increase resistance to ionizing radiation
    • Lee JM, Bernstein A. p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci USA 1993; 90: 5742-6.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5742-5746
    • Lee, J.M.1    Bernstein, A.2
  • 68
    • 9344266882 scopus 로고    scopus 로고
    • The p53 gene is a potent determinant of chemosensitivity and radiosensisitivity in gastric and colorectal cancers
    • Hamada M, Fujiwara T, Hizuta A, Gochi A, Naomoto Y, Takakura N et al. The p53 gene is a potent determinant of chemosensitivity and radiosensisitivity in gastric and colorectal cancers. J Cancer Res Clin Oncol 1996; 122: 360-5.
    • (1996) J Cancer Res Clin Oncol , vol.122 , pp. 360-365
    • Hamada, M.1    Fujiwara, T.2    Hizuta, A.3    Gochi, A.4    Naomoto, Y.5    Takakura, N.6
  • 69
    • 0029956081 scopus 로고    scopus 로고
    • Specific p53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
    • Aas T, Borresen AL, Geisler S, Smith-Sorensen B, Johnsen H, Vargaug JE et al. Specific p53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients. Nature Med 1996; 2: 811-14.
    • (1996) Nature Med , vol.2 , pp. 811-814
    • Aas, T.1    Borresen, A.L.2    Geisler, S.3    Smith-Sorensen, B.4    Johnsen, H.5    Vargaug, J.E.6
  • 70
    • 0029944241 scopus 로고    scopus 로고
    • A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation
    • Lutzker S, Levine AJ. A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation. Nature Med 1996; 2: 804-10.
    • (1996) Nature Med , vol.2 , pp. 804-810
    • Lutzker, S.1    Levine, A.J.2
  • 71
    • 0028901034 scopus 로고
    • Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
    • Fan S, Smith ML, Rivet DJ II, Duba D, Zhan Q, Kohn KW et al. Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 1995; 55: 1649-54.
    • (1995) Cancer Res , vol.55 , pp. 1649-1654
    • Fan, S.1    Smith, M.L.2    Rivet II, D.J.3    Duba, D.4    Zhan, Q.5    Kohn, K.W.6
  • 72
    • 0029094835 scopus 로고
    • The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage
    • Xu C, Meikrantz W, Schlegel R, Sager R. The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage. Proc Natl Acad Sci USA 1995; 92: 7829-33.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7829-7833
    • Xu, C.1    Meikrantz, W.2    Schlegel, R.3    Sager, R.4
  • 73
    • 0026488680 scopus 로고
    • Mutations in the p53 gene in radiation-sensitive and -resistant human squamous carcinoma cells
    • Jung M, Notario V, Dritschilo A. Mutations in the p53 gene in radiation-sensitive and -resistant human squamous carcinoma cells. Cancer Res 1992; 52: 6390-3.
    • (1992) Cancer Res , vol.52 , pp. 6390-6393
    • Jung, M.1    Notario, V.2    Dritschilo, A.3
  • 74
    • 0028363282 scopus 로고
    • Clinical utility of the immunocytochemical detection of p53 protein in cytological specimens
    • Dowell SP, Wilson POG, Derias NW, Lane DP, Hall PA. Clinical utility of the immunocytochemical detection of p53 protein in cytological specimens. Cancer Res 1994; 54: 2914-18.
    • (1994) Cancer Res , vol.54 , pp. 2914-2918
    • Dowell, S.P.1    Pog, W.2    Derias, N.W.3    Lane, D.P.4    Hall, P.A.5
  • 75
    • 14444286170 scopus 로고    scopus 로고
    • Colorectal cancer mutations in whole gut lavage fluid
    • Abstract
    • Potter MA, Morris RG, Ferguson A, Wyllie AH. Colorectal cancer mutations in whole gut lavage fluid. Br J Surg 1997; 84: 1590 (Abstract).
    • (1997) Br J Surg , vol.84 , pp. 1590
    • Potter, M.A.1    Morris, R.G.2    Ferguson, A.3    Wyllie, A.H.4
  • 77
    • 0025868669 scopus 로고
    • Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA
    • Mukhopadhyay T, Tainsky M, Cavender AC, Roth JA. Specific inhibition of K-ras expression and tumorigenicity of lung cancer cells by antisense RNA. Cancer Res 1991; 51: 1744-8.
    • (1991) Cancer Res , vol.51 , pp. 1744-1748
    • Mukhopadhyay, T.1    Tainsky, M.2    Cavender, A.C.3    Roth, J.A.4
  • 78
    • 0028143201 scopus 로고
    • Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model
    • Fujiwara T, Cai DW, Georges RN, Mukhopadhyay T, Grimm EA, Roth JA. Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model. J Natl Cancer Inst 1994; 86: 1458-62.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1458-1462
    • Fujiwara, T.1    Cai, D.W.2    Georges, R.N.3    Mukhopadhyay, T.4    Grimm, E.A.5    Roth, J.A.6
  • 80
    • 0030781397 scopus 로고    scopus 로고
    • Novel combination therapy for human colon cancer with adenvirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent
    • Ogawa N, Fujiwara T, Kagawa S, Nishizaki M, Morimoto Y, Tanida T et al. Novel combination therapy for human colon cancer with adenvirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent. Int J Cancer 1997; 73: 367-70.
    • (1997) Int J Cancer , vol.73 , pp. 367-370
    • Ogawa, N.1    Fujiwara, T.2    Kagawa, S.3    Nishizaki, M.4    Morimoto, Y.5    Tanida, T.6
  • 81
  • 82
    • 0344188096 scopus 로고    scopus 로고
    • An adenovirus mutant that replicates selectively in p53-deficient human tumour cells
    • Bischoff JR, Kirn DH, Williams A, Heise C, Horn S, Muna M et al. An adenovirus mutant that replicates selectively in p53-deficient human tumour cells. Science 1996; 274: 373-6.
    • (1996) Science , vol.274 , pp. 373-376
    • Bischoff, J.R.1    Kirn, D.H.2    Williams, A.3    Heise, C.4    Horn, S.5    Muna, M.6
  • 83
    • 0030917202 scopus 로고    scopus 로고
    • ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
    • Heise C, Sampson-Johannes A, Williams A, McCormick F, Von Hoff DD, Kirn DH. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nature Med 1997; 3: 639-45.
    • (1997) Nature Med , vol.3 , pp. 639-645
    • Heise, C.1    Sampson-Johannes, A.2    Williams, A.3    McCormick, F.4    Von Hoff, D.D.5    Kirn, D.H.6
  • 84
    • 0028673142 scopus 로고
    • Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases
    • Hupp TR, Lane DP. Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases. Cold Spring Harbor Symp Biol 1994; 59: 195-206.
    • (1994) Cold Spring Harbor Symp Biol , vol.59 , pp. 195-206
    • Hupp, T.R.1    Lane, D.P.2
  • 85
    • 0028966935 scopus 로고
    • Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases
    • Takenaka I, Morin F, Seizinger BR, Kley N. Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases. J Biol Chem 1995; 270: 5405-11.
    • (1995) J Biol Chem , vol.270 , pp. 5405-5411
    • Takenaka, I.1    Morin, F.2    Seizinger, B.R.3    Kley, N.4
  • 86
    • 0028845158 scopus 로고
    • Small peptides activate the latent sequence-specific DNA binding function of p53
    • Hupp TR, Sparks A, Lane DP. Small peptides activate the latent sequence-specific DNA binding function of p53. Cell 1995; 83: 237-45.
    • (1995) Cell , vol.83 , pp. 237-245
    • Hupp, T.R.1    Sparks, A.2    Lane, D.P.3
  • 87
    • 0028910191 scopus 로고
    • p53 derived from human tumour cell lines and containing distinct point mutations can be activated to bind its consensus target sequence
    • Niewolik D, Vojtesek B, Kovarik J. p53 derived from human tumour cell lines and containing distinct point mutations can be activated to bind its consensus target sequence. Oncogene 1995; 10: 881-90.
    • (1995) Oncogene , vol.10 , pp. 881-890
    • Niewolik, D.1    Vojtesek, B.2    Kovarik, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.