Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes

International Journal of Pharmaceutics

Volumn 416, Issue 2, 2011, Pages 433-442

  Coimbra, Maria ^a   Isacchi, Benedetta ^b   Van Bloois, Louis ^a   Torano, Javier Sastre ^b   Ket, Aldo ^a   Wu, Xiaojie ^a   Broere, Femke ^c   Metselaar, Josbert M ^a   Rijcken, Cristianne J F ^a   Storm, Gert ^a   Bilia, Rita ^b   Schiffelers, Raymond M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Caffeic acid; Carvacrol; Inflammation; Liposome; N (3 oxo dodecanoyl) l homoserine lactone; Pterostilbene; Resveratrol; Thymol

Indexed keywords

CAFFEIC ACID; CARVACROL; CARVACROL DISODIUM PHOSPHATE; LIPOSOME; N (3 OXODODECANOYL)HOMOSERINE LACTONE; PTEROSTILBENE; PTEROSTILBENE DISODIUM PHOSPHATE; RESVERATROL; SERUM ALBUMIN; SODIUM DIHYDROGEN PHOSPHATE; SOLVENT; STILBENE DERIVATIVE; THYMOL; UNCLASSIFIED DRUG; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CIS TRANS ISOMERISM; CONTROLLED STUDY; DERIVATIZATION; DRUG BIOAVAILABILITY; DRUG DEGRADATION; DRUG FORMULATION; DRUG ISOLATION; DRUG SOLUBILITY; DRUG STABILITY; ENCAPSULATION; FEMALE; HEAD AND NECK CARCINOMA; LIPID BILAYER; LIPOSOMAL DELIVERY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL AGENTS; CARCINOMA, SQUAMOUS CELL; DRUG STABILITY; FEMALE; HEAD AND NECK NEOPLASMS; LIPOSOMES; MICE; MICE, INBRED BALB C; MICE, NUDE; OXIDATION-REDUCTION; SOLUBILITY;

EID: 79956106542     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.01.056     Document Type: Article

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