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Volumn 2, Issue 2, 2011, Pages 104-108

Translational connection of TGFβ signalingphosphorylation of eEF1A1 by TβR-I inhibits protein synthesis

Author keywords

Cancer; EEF1A1; Elongation; Protein; TGF ; Translation

Indexed keywords

ELONGATION FACTOR; PROTEIN EEF1A1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

EID: 79956060013     PISSN: 21541248     EISSN: 21541256     Source Type: Journal    
DOI: 10.4161/sgtp.2.2.15603     Document Type: Article
Times cited : (2)

References (29)
  • 1
    • 0027292202 scopus 로고
    • Tissue-dependent variation in the expression of elongation factor-1 alpha isoforms: Isolation and characterisation of a cDNA encoding a novel variant of human elongation-factor 1alpha
    • Knudsen SM, Frydenberg J, Clark BF, Leffers H. Tissue-dependent variation in the expression of elongation factor-1 alpha isoforms: isolation and characterisation of a cDNA encoding a novel variant of human elongation-factor 1alpha. Eur J Biochem 1993; 215:549-54.
    • (1993) Eur J Biochem , vol.215 , pp. 549-554
    • Knudsen, S.M.1    Frydenberg, J.2    Clark, B.F.3    Leffers, H.4
  • 2
    • 0027095979 scopus 로고
    • Tissue-specific expression in mammalian brain, heart and muscle of S1, a member of the elongation factor-1alpha gene family
    • Lee S, Francoeur AM, Liu S, Wang E. Tissue-specific expression in mammalian brain, heart and muscle of S1, a member of the elongation factor-1alpha gene family. J Biol Chem 1992; 267:24064-8.
    • (1992) J Biol Chem , vol.267 , pp. 24064-24068
    • Lee, S.1    Francoeur, A.M.2    Liu, S.3    Wang, E.4
  • 3
    • 0021891865 scopus 로고
    • Eukaryotic protein synthesis
    • Moldave K. Eukaryotic protein synthesis. Annu Rev Biochem 1985; 54:1109-49.
    • (1985) Annu Rev Biochem , vol.54 , pp. 1109-1149
    • Moldave, K.1
  • 4
    • 0028988998 scopus 로고
    • Elongation factor 1alpha, translation and the cytoskeleton
    • Condeelis J. Elongation factor 1alpha, translation and the cytoskeleton. Trends Biochem Sci 1995; 20:169-70.
    • (1995) Trends Biochem Sci , vol.20 , pp. 169-170
    • Condeelis, J.1
  • 5
    • 0030843268 scopus 로고    scopus 로고
    • Upregulation of the elongation factor-1alpha gene by p53 in association with death of an erythroleukemic cell line
    • Kato MV, Sato H, Nagayoshi M, Ikawa Y. Upregulation of the elongation factor-1alpha gene by p53 in association with death of an erythroleukemic cell line. Blood 1997; 90:1373-8.
    • (1997) Blood , vol.90 , pp. 1373-1378
    • Kato, M.V.1    Sato, H.2    Nagayoshi, M.3    Ikawa, Y.4
  • 6
    • 4143091385 scopus 로고    scopus 로고
    • The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: Review article
    • Lamberti A, Caraglia M, Longo O, Marra M, Abbruzzese A, Arcari P. The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: review article. Amino Acids 2004; 26:443-8.
    • (2004) Amino Acids , vol.26 , pp. 443-448
    • Lamberti, A.1    Caraglia, M.2    Longo, O.3    Marra, M.4    Abbruzzese, A.5    Arcari, P.6
  • 7
    • 36248947214 scopus 로고    scopus 로고
    • The expression levels of the transla-tional factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade
    • Grassi G, Scaggiante B, Farra R, Dapas B, Agostini F, Baiz D, et al. The expression levels of the transla-tional factors eEF1A 1/2 correlate with cell growth but not apoptosis in hepatocellular carcinoma cell lines with different differentiation grade. Biochimie 2007; 89:1544-52.
    • (2007) Biochimie , vol.89 , pp. 1544-1552
    • Grassi, G.1    Scaggiante, B.2    Farra, R.3    Dapas, B.4    Agostini, F.5    Baiz, D.6
  • 8
    • 57749183214 scopus 로고    scopus 로고
    • EF1A1-actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells
    • Zhang J, Guo H, Mi Z, Gao C, Bhattacharya S, Li J, Kuo PC. EF1A1-actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells. Exp Cell Res 2009; 315:304-12.
    • (2009) Exp Cell Res , vol.315 , pp. 304-312
    • Zhang, J.1    Guo, H.2    Mi, Z.3    Gao, C.4    Bhattacharya, S.5    Li, J.6    Kuo, P.C.7
  • 9
    • 77958493043 scopus 로고    scopus 로고
    • Increased expression of elongation factor-1alpha is significantly correlated with poor prognosis of human prostate cancer
    • Liu H, Ding J, Chen F, Fan B, Gao N, Yang Z, Qi L. Increased expression of elongation factor-1alpha is significantly correlated with poor prognosis of human prostate cancer. Scand J Urol Nephrol 2010; 44:277-83.
    • (2010) Scand J Urol Nephrol , vol.44 , pp. 277-283
    • Liu, H.1    Ding, J.2    Chen, F.3    Fan, B.4    Gao, N.5    Yang, Z.6    Qi, L.7
  • 10
    • 0029911314 scopus 로고    scopus 로고
    • Elongation factor-1alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma
    • Edmonds BT, Wyckoff J, Yeung YG, Wang Y, Stanley ER, Jones J, et al. Elongation factor-1alpha is an overexpressed actin binding protein in metastatic rat mammary adenocarcinoma. J Cell Sci 1996; 109:2705-14.
    • (1996) J Cell Sci , vol.109 , pp. 2705-2714
    • Edmonds, B.T.1    Wyckoff, J.2    Yeung, Y.G.3    Wang, Y.4    Stanley, E.R.5    Jones, J.6
  • 11
    • 0036635310 scopus 로고    scopus 로고
    • Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer
    • Anand N, Murthy S, Amann G, Wernick M, Porter LA, Cukier IH, et al. Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer. Nat Genet 2002; 31:301-5.
    • (2002) Nat Genet , vol.31 , pp. 301-305
    • Anand, N.1    Murthy, S.2    Amann, G.3    Wernick, M.4    Porter, L.A.5    Cukier, I.H.6
  • 13
    • 78649872112 scopus 로고    scopus 로고
    • Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas
    • Van Goietsenoven G, Hutton J, Becker JP, Lallemand B, Robert F, Lefranc F, et al. Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas. FASEB J 2010; 24:4575-84.
    • (2010) FASEB J , vol.24 , pp. 4575-4584
    • van Goietsenoven, G.1    Hutton, J.2    Becker, J.P.3    Lallemand, B.4    Robert, F.5    Lefranc, F.6
  • 14
    • 0028892669 scopus 로고
    • Phosphorylation of elongation factor 1 (EF-1) by protein kinase C stimulates GDP/GTP-exchange activity
    • Peters HI, Chang YW, Traugh JA. Phosphorylation of elongation factor 1 (EF-1) by protein kinase C stimulates GDP/GTP-exchange activity. Eur J Biochem 1995; 234:550-6.
    • (1995) Eur J Biochem , vol.234 , pp. 550-556
    • Peters, H.I.1    Chang, Y.W.2    Traugh, J.A.3
  • 16
    • 0021101952 scopus 로고
    • Methylation of elongation factor 1alpha in mouse 3T3B and 3T3B/ SV40 cells
    • Coppard NJ, Clark BF, Cramer F. Methylation of elongation factor 1alpha in mouse 3T3B and 3T3B/ SV40 cells. FEBS Lett 1983; 164:330-4.
    • (1983) FEBS Lett , vol.164 , pp. 330-334
    • Coppard, N.J.1    Clark, B.F.2    Cramer, F.3
  • 17
    • 34548638338 scopus 로고    scopus 로고
    • New concepts in tissue-specific metastases
    • Massague J. New concepts in tissue-specific metastases. Clin Adv Hematol Oncol 2003; 1:576-7
    • (2003) Clin Adv Hematol Oncol , vol.1 , pp. 576-577
    • Massague, J.1
  • 18
    • 0037621860 scopus 로고    scopus 로고
    • Imamura T Regulation of TGFbeta signaling and its roles in progression of tumors
    • Miyazono K, Suzuki H, Imamura T Regulation of TGFbeta signaling and its roles in progression of tumors. Cancer Sci 2003; 94:230-4.
    • (2003) Cancer Sci , vol.94 , pp. 230-234
    • Miyazono, K.1    Suzuki, H.2
  • 19
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGFbeta signaling
    • Zhang YE. Non-Smad pathways in TGFbeta signaling. Cell Res 2009; 19:128-39.
    • (2009) Cell Res , vol.19 , pp. 128-139
    • Zhang, Y.E.1
  • 20
    • 34548386720 scopus 로고    scopus 로고
    • TGFbeta activates Erk MAP kinase signalling through direct phosphorylation of ShcA
    • Lee MK, Pardoux C, Hall MC, Lee PS, Warburton D, Qing J, et al. TGFbeta activates Erk MAP kinase signalling through direct phosphorylation of ShcA. EMBO J 2007; 26:3957-67
    • (2007) EMBO J , vol.26 , pp. 3957-3967
    • Lee, M.K.1    Pardoux, C.2    Hall, M.C.3    Lee, P.S.4    Warburton, D.5    Qing, J.6
  • 21
    • 14844364701 scopus 로고    scopus 로고
    • Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
    • Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 2005; 307:1603-9.
    • (2005) Science , vol.307 , pp. 1603-1609
    • Ozdamar, B.1    Bose, R.2    Barrios-Rodiles, M.3    Wang, H.R.4    Zhang, Y.5    Wrana, J.L.6
  • 22
    • 77957230094 scopus 로고    scopus 로고
    • Phosphorylation of eEF1A1 at Ser300 by TbetaR-I results in inhibition of mRNA translation
    • Lin KW, Yakymovych I, Jia M, Yakymovych M, Souchelnytskyi S. Phosphorylation of eEF1A1 at Ser300 by TbetaR-I results in inhibition of mRNA translation. Curr Biol 2010; 20:1615-25.
    • (2010) Curr Biol , vol.20 , pp. 1615-1625
    • Lin, K.W.1    Yakymovych, I.2    Jia, M.3    Yakymovych, M.4    Souchelnytskyi, S.5
  • 24
    • 0033569767 scopus 로고    scopus 로고
    • Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both trans-lational fidelity and the requirement for nucleotide exchange
    • Carr-Schmid A, Durko N, Cavallius J, Merrick WC, Kinzy TG. Mutations in a GTP-binding motif of eukaryotic elongation factor 1A reduce both trans-lational fidelity and the requirement for nucleotide exchange. J Biol Chem 1999; 274:30297-302.
    • (1999) J Biol Chem , vol.274 , pp. 30297-30302
    • Carr-Schmid, A.1    Durko, N.2    Cavallius, J.3    Merrick, W.C.4    Kinzy, T.G.5
  • 25
    • 0032788546 scopus 로고    scopus 로고
    • Mutations in elongation factor 1beta, a guanine nucleotide exchange factor, enhance translational fidelity
    • Carr-Schmid A, Valente L, Loik VI, Williams T, Starita LM, Kinzy TG. Mutations in elongation factor 1beta, a guanine nucleotide exchange factor, enhance translational fidelity. Mol Cell Biol 1999; 19:5257-66.
    • (1999) Mol Cell Biol , vol.19 , pp. 5257-5266
    • Carr-Schmid, A.1    Valente, L.2    Loik, V.I.3    Williams, T.4    Starita, L.M.5    Kinzy, T.G.6
  • 26
    • 68149126140 scopus 로고    scopus 로고
    • Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation
    • Soares DC, Barlow PN, Newbery HJ, Porteous DJ, Abbott CM. Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation. PLoS One 2009; 4:6315.
    • (2009) PLoS One , vol.4 , pp. 6315
    • Soares, D.C.1    Barlow, P.N.2    Newbery, H.J.3    Porteous, D.J.4    Abbott, C.M.5
  • 28
    • 0033638335 scopus 로고    scopus 로고
    • Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:EEF1Balpha
    • Andersen GR, Pedersen L, Valente L, Chatterjee I, Kinzy TG, Kjeldgaard M, Nyborg J. Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha. Mol Cell 2000; 6:1261-6.
    • (2000) Mol Cell , vol.6 , pp. 1261-1266
    • Andersen, G.R.1    Pedersen, L.2    Valente, L.3    Chatterjee, I.4    Kinzy, T.G.5    Kjeldgaard, M.6    Nyborg, J.7
  • 29
    • 79952653328 scopus 로고    scopus 로고
    • Eukaryotic elongation factor eEF1A1 promotes and Ser300 mutants of eEF1A1 inhibit transition through the S and G2/M phases of the cell cycle
    • Lin KW, Souchelnytskyi S. Eukaryotic elongation factor eEF1A1 promotes and Ser300 mutants of eEF1A1 inhibit transition through the S and G2/M phases of the cell cycle. J Cell Mol Biol 2010; 8:125-30.
    • (2010) J Cell Mol Biol , vol.8 , pp. 125-130
    • Lin, K.W.1    Souchelnytskyi, S.2


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