Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway

Journal of Biological Chemistry

Volumn 279, Issue 41, 2004, Pages 42709-42718

  Qiao, Meng ^a   Shapiro, Paul ^a   Kumar, Rakesh ^b   Passaniti, Antonino ^c  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGENS; CELLS; DNA; GROWTH KINETICS; PROTEINS; SIGNALING; TUMORS;

DNA BINDING; ENDOTHELIAL CELLS; PHOSPHORYLATION; TUMORIGENESIS;

INSULIN;

2 MORPHOLINO 8 PHENYLCHROMONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; TRANSCRIPTION FACTOR RUNX2;

ARTICLE; CELL PROLIFERATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOTTING, WESTERN; BUTADIENES; CELL DIVISION; CELL LINE; CELL MOVEMENT; CELL NUCLEUS; CHROMONES; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MORPHOLINES; NEOPLASM PROTEINS; NITRILES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 5644236459     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M404480200     Document Type: Article

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